Hematology Lab Part 1 Flashcards Preview

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1
Q

Functions of Blood

A

Provides a medium for the maintenance of homeostasis in the cell’s environment Functions as a transportation system, bringing nutrients and oxygen to the cells and removing wastes and carbon dioxide from interstitial fluid around the cells Integrates various organs through hormones Provide buffers for acid-base balance Destroys foreign organisms through phagocytosis and antibody action Provide distribution of body heat & heat conservation Prevent its own loss through hemostasis (coagulation) mechanisms

2
Q

The percent volume of whole blood that is occupied by red blood cells

A

Hematocrit

3
Q

Determined by comparing the height of the red cell in the centrifuged tube to the height of the total column of blood

A

Blood Hematocrit

4
Q

Normal values of male Hematocrit values and range

A

Average = 46% Range = 43 - 49%

5
Q

Average = 46% Range = 43 - 49%

A

Males Hematocrit Levels

6
Q

Average = 41% Range = 36 - 45%

A

Females Hematocrit Levels

7
Q

Severe Anemia

A

Hematocrit may fall to as low as 15%

8
Q

Hematocrit may fall to as low as 15%

A

Severe Anemia

9
Q

Normal Values of Females Hematocrit & Range

A

Average = 41% Range = 36 - 45%

10
Q

Hematocrit

A

The percent volume of whole blood that is occupied by red blood cells

11
Q

Polycythemia

A

Hematocrit may rise to as high as 70%

12
Q

Hematocrit rises to as high as 70%

A

Polycythemia

13
Q

Calculating Hematocrit

A

Hct (%) = height of red cells (mm) / height of red cells and plasma (mm) x 100

14
Q

Amount of O2 which blood can carry is closely related to

A

Concentration of hemoglobin

15
Q

Each gram of hemoglobin when completely saturated is capable of carrying

A

1.34 ml of oxygen

16
Q

34% of the red blood cell by weight is

A

Hemoglobin; it is essentially a bag of hemoglobin

17
Q

Average = 15.4 g/100 ml blood Range = 13.6 to 17.2

A

Average concentration/Range of Hemoglobin in Males

18
Q

Average: 13.3 g/100 ml blood Range: 11.5 to 15.0

A

Average concentration/Range of Hemoglobin in Females

19
Q

Anemic

A

Less than 10g/100ml of blood

20
Q

Less than 10g/100ml of blood

A

Anemic

21
Q

Calculation of Total Maximum Oxygen Carrying Capacity

A

Total blood Hb (g) = blood volume (ml of blood) X hemoglobin concentration (g Hb/ml of blood) Total oxygen carrying capacity = (total g Hb) X (1.34 ml O2/g Hb)

22
Q

Each gram of hemoglobin is capable of carrying

A

1.34 ml of oxygen when completely saturated

22
Q

Strenuous exercise, rheumatic fever, severe burns

A

Neutrophilic Leukocytosis

23
Q

Blood Volume for Females

A

65 ml blood per kilogram body weight +/- 10% (1 kg = 2.2 lbs)

24
Q

Differential white blood cell count

A

The percentage of each type of white cell in the total leukocyte population is calculated

25
Q

Average concentration/range of hemoglobin in Males

A

Average = 15.4 g/100 ml blood Range = 13.6 to 17.2

26
Q

Neutrophilic Leukopenia

A

Protozoan infections, malnutrition, aplastic anemia

27
Q

Neutrophilic Leukocytosis

A

Strenuous exercise, rheumatic fever, severe burns

28
Q

Scarlet fever, parasitic infections, allergic reactions

A

Eosinophilia

29
Q

Average concentration/Range of Hemoglobin in Females

A

Average: 13.3 g/100 ml blood Range: 11.5 to 15.0

30
Q

Protozoan infections, malnutrition, aplastic anemia

A

Neutrophilic Leukopenia

31
Q

Lymphocytosis

A

Mumps, German measles, whooping cough

32
Q

Blood volume for Males

A

79 ml blood per kilogram body +/- 10%

33
Q

Mumps, German measles, whooping cough

A

Lymphocytosis

34
Q

Eosinophilia

A

Scarlet fever, parasitic infections, allergic reactions

35
Q

Monocytosis

A

Chronic diseases, such as tuberculosis & leukemia

36
Q

Granulocytes

A

Neutrophils Eosinophils Basophils

37
Q

Chronic diseases, such as tuberculosis & leukemia

A

Monocytosis

38
Q

Lymphocytopenia

A

Administration of glucocorticoid drugs

39
Q

Administration of glucocorticoid drugs

A

Lymphocytopenia

40
Q

Eosinophils

A

2-4% of total WBC 13 microns diameter Bilobed nucleus Coarse red-orange cytoplasmic granules, blue-purple nucleus

41
Q

Neutrophils Eosinophils Basophils

A

Granulocytes

42
Q

Neutrophils

A

65% of total WBC 10-12 microns diameter Multi-lobed (3 or more) nucleus Small pink cytoplasmic granules, purple nucleus

43
Q

Small Lymphocytes

A

20-25% of total WBC 7 microns diameter Very large, spherical nucleus surrounded by a thin cytoplasm Light blue cytoplasm (nongranular), deep blue or purple nucleus

44
Q

65% of total WBC 10-12 microns diameter Multi-lobed (3 or more) nucleus Small pink cytoplasmic granules, purple nucleus

A

Neutrophils

45
Q

2-4% of total WBC 13 microns diameter Bilobed nucleus Coarse red-orange cytoplasmic granules, blue-purple nucleus

A

Eosinophils

46
Q

Basophils

A

0.5% of total WBC 14 microns diameter Bilobed nucleus Black nucleus is usually completely obscured by large, deep-blue or reddish-purple cytoplasmic granules

47
Q

0.5% of total WBC 14 microns diameter Bilobed nucleus Black nucleus is usually completely obscured by large, deep-blue or reddish-purple cytoplasmic granules

A

Basophils

48
Q

Agranulocytes (Mononuclear Leukocytes)

A

Small Lymphocytes Large Lymphocytes Monocytes

49
Q

20-25% of total WBC 7 microns diameter Very large, spherical nucleus surrounded by a thin cytoplasm Light blue cytoplasm (nongranular), deep blue or purple nucleus

A

Small Lymphocytes

50
Q

Another name for Granulocytes

A

Polymorphonuclear Leukocytes

51
Q

Large Lymphocytes

A

3% of total WBC 10 microns diameter Large oval, indented nucleus Light blue cytoplasm (nongranular), dark purple nucleus

52
Q

Erythrocyte

A

Another name for a RBC

53
Q

Monocytes

A

3-7% of total WBC 15 microns diameter Large, deeply indented nucleus (horseshoe-shaped) Light blue-gray cytoplasm (nongranular), blue or purple nucleus

54
Q

3-7% of total WBC 15 microns diameter Large, deeply indented nucleus (horseshoe-shaped) Light blue-gray cytoplasm (nongranular), blue or purple nucleus

A

Monocytes

55
Q

Normally, each 100 mL of blood will contain approximately:

A

15 grams of hemoglobin, which is distributed among the 500 billion red cells in each 100 mL of whole blood

56
Q

Another name for red blood cell

A

Erythrocyte

57
Q

3% of total WBC 10 microns diameter Large oval, indented nucleus Light blue cytoplasm (nongranular), dark purple nucleus

A

Large Lymphocytes

58
Q

In our lab we measured our hemoglobin concentration in

A

% = g Hb/100 ml of blood

59
Q

Major difficulties seldom develop until

A

level of 7.5g/100ml of blood is reached

60
Q

A rat has approximately how much blood per kilogram?

A

70 ml blood per kilogram body weight

61
Q

average leukocyte count

A

7,500/mm^3 average

62
Q

Another name for Agranulocytes

A

Mononuclear Leukocytes

63
Q

Function of Heparin

A

inhibits coagulation