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Flashcards in Hepatic diseases and conditions Deck (15):
1

What is hepatorenal syndrome

medical condition that consist of rapid deterioration in kidney function. There vasodilation in lungs due to Nitric oxide.

2

What are characteristics of hepatorenal syndromes

its over perfusion compared to ventilation. SOB is worse in upright position and there is hypoxemia low levels of O2 in arteries.

also, rapid renal failure w/ patient
rise in BUN and creatinine levels
fall in GFR

3

What is hemochromatosis

it is excess iron absorption that deposits in liver, pancreas, heart, joints, endocrine organs

4

What ancestry is common to hemochromatosis

Northern European

5

What are the causes of hemochromatosis

Primary: Heredity haemchromatosis (HFE gene - C282Y)
Secondary: transfusions, long term hemodialysis, hemolytic anemia

6

What are the symptoms of hemochromatosis

Bronzing of skin, arthritis cirrhosis, restrictive cardiomyopathy, Hepatocellular carcinoma, DM, Chronic pancreatitis, infertility

7

What wilson's disease

hepatocellular degeneration where there is impaired copper excretion into bile

8

What are the signs and symptoms of wilson's disease

Liver- hepatosplenomegaly
Brain - dementia, Movement issues, depression
Eyes: kayser- Flescher ring, Cu deposits in Descent membrane

9

What do you measure for Wilson disease

Ceruloplasmin

10

What is alpha-1 anti-trypsin Def.?

Autosomal recessive where the protein folding is affected and accumulates in the liver.

11

What causes alpha-1 anti-trypsin def. ?

Panacinar Emphysema

12

What is Hepatic Tumor?

It is a benign glandular epithelia tumor

13

What is it associated with Hepatic tumor

OCP

14

What are the risk factors or causes of Hepatic tumor

Hepatitis B and C
Hemochromatosis
Wilson's Disease
Alpha-1 anti-trypsin
Primary Biliary cirrhosis

15

What is the diagnostic test for hepatic tumor

AFP