Viral Hepatitis and autoimmune hepatitis Flashcards Preview

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Flashcards in Viral Hepatitis and autoimmune hepatitis Deck (20):
1

Name the characteristics of Hep. A

Family: Picorna
Generation: RNA
Transmission: fecal-Oral
Ono.city: No
Complication: Acute liver Failure or Death

2

Name the characteristics of Hep. B

Family: Hepadana
Generation: DNA
Transmission: sexual, Parenteral, Oral
Ono. City: yes
Complication: liver cancer

3

Name the characteristics of Hep. C

Family: Flavi
Generation: RNA
Transmission: Parental Sexual
Ono. city: Yes
Complication: liver Cancer

4

Name the characteristics of Hep. D

Family: Delta
Generation: RNA
Transmission: PNP
Ono.city: N/A
Complication: Co-infection with Hep. B

5

Name the characteristics of Hep. E

Family: Calci
Generation: RNA
Transmission: fecal- oral
Ono. city: No
Complication: Association with Pregnancy

6

What are the risk for Hep. B

People with sexually transmitted diseases
Men to Men
IV drug users
Infant born form HBV mothers
More than 1 sexual partners in the last 6 months
Health care workers
Hemodialysis patients

7

What are the markers for Hep. B

HBsAg- acute or chronic infection
Anti-HBs - markers of immunity
Hepatits B core antibody (anti-HBC)- current or prior infection
IgM - indicative of infection in the previous 6 months
IgG - more distant HBV infection that is resolving
HBeAg - high infectivity
anti-HBe - correlates w/ low rate replication
HBV-DNA - active replication great for monitoring treatment

8

What are the characteristics of an acute viral hepatitis

mottled appearance
lympoplasmacytic infiltrate
limited portal inflammations
necrosis of hepatocyte

9

What are the characteristics of chronic viral hepatitis

lymphoplasmacytic infiltrate
mononuclear portal infiltrate
scarring necrosis

10

What are the types of autoimmune hepatitis

type 1 and 2

11

What is autoimmune hepatitis

it is a chronic, autoimmune disease of the live that occurs when the body's immune system attacks liver cells and causes inflammation.

12

What are characteristics of type 1 autoimmune hepatitis

middle age women
Anti-smooth muscle antibody
Anti-nuclear antibody

13

What are the characteristics of type 2 autoimmune hepatitis

in children and teenagers
Anti-LKM1 antibody

14

What is the treatment for autoimmune hepatitis

Corticosteroids

15

What are the drugs in drugs induced liver damage

acetaminophen
isoniazid
methotrexate
amiodarone
statins

16

What are the notes of acetaminophen

most common hepatotoxin cause acute liver failure
P450 system
Elevated LFT greater than 10g
necrosis around zone III
treatment: N-acetylcyst increase synthesis of glutathione

17

What are the notes on isoniazid

Anti-TB drug

18

What are the notes on methotrexate

anti-cancer drug

19

What are the notes on amiodarone

anti-arrhythmic drug

20

What are the notes on statins

anti-cholesterol drugs