Histology I: Lecture 9 Flashcards
histology
the study of the normal structure of tissues
tissue
-groups of cells, similar in structure, that cooperate to perform a function
-cells embedded in ECM of ground substance and fibrous proteins
primary tissue classes
epithelial, connective, nervous, muscular
epithelial tissue
sheets of tightly packed cells, little visible ECM; coverings and linings or glands
connective tissue
loosely scattered cells; ECM most prominent; bind, support, protect, connect parts of the body
muscular tissue
long, cylindrical, or spindle shaped cells; little visible ECM; contractile/generate force
nervous tissue
mostly fluid ECM; process and transmit information
extracellular matrix (ECM)
ground substance and fibrous proteins that surround cells
ground substance
EC fluid, gel, or solid; water, ions, nutrients, and macromolecules: glycosaminoglycans, proteoglycans, and glycoproteins
fibrous proteins
collagen fibers, elastic fibers, and reticular fibers
glycosaminoglycans (GAGs)
strands of ‘bottle brush’; charged- attract water molecules
proteoglycans
‘bottle brush’; slow pathogens, connect ECM to cell membranes
glycoproteins
bind plasma membrane to EC collagen and proteoglycans
collagenous fibers
(thickest) 25% of bodies protein; tough- resist stretching and tension
reticular fibers
(median thickness) thin collagen fibers with glycoprotein coat; form spongelike frameworks for spleen and lymph nodes
elastic fibers
(thinnest) made of elastin-coiled protein with ability to recoil (elasticity)
cell shapes
squamous, cuboidal, columnar, polygonal, stellate, spheroidal, discoid, fusiform, fibrous
cell junctions
physical connections between tissue cells;
types: tight junctions, desmosomes, and gap junctions
tight junctions
integral membrane proteins of adjacent cells lock together to form an impermeable seal
desmosomes
integral membrane proteins of adjacent cells interweave between cells and connect to intermediate filaments within cells; resist mechanical stress
gap junctions
interlocked protein pores that allow substances to pass between cells
(broad) types of epithelial tissue
- coverings and linings
- glands
epithelial characteristics
polarity, specialized contacts, avascular, supported by connective tissue, innervated, regeneration
structural characteristics of epithelium
cell shape, number of layers