Histology I: Lecture 9 Flashcards

1
Q

histology

A

the study of the normal structure of tissues

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2
Q

tissue

A

-groups of cells, similar in structure, that cooperate to perform a function
-cells embedded in ECM of ground substance and fibrous proteins

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3
Q

primary tissue classes

A

epithelial, connective, nervous, muscular

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4
Q

epithelial tissue

A

sheets of tightly packed cells, little visible ECM; coverings and linings or glands

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5
Q

connective tissue

A

loosely scattered cells; ECM most prominent; bind, support, protect, connect parts of the body

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6
Q

muscular tissue

A

long, cylindrical, or spindle shaped cells; little visible ECM; contractile/generate force

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7
Q

nervous tissue

A

mostly fluid ECM; process and transmit information

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8
Q

extracellular matrix (ECM)

A

ground substance and fibrous proteins that surround cells

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9
Q

ground substance

A

EC fluid, gel, or solid; water, ions, nutrients, and macromolecules: glycosaminoglycans, proteoglycans, and glycoproteins

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10
Q

fibrous proteins

A

collagen fibers, elastic fibers, and reticular fibers

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11
Q

glycosaminoglycans (GAGs)

A

strands of ‘bottle brush’; charged- attract water molecules

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12
Q

proteoglycans

A

‘bottle brush’; slow pathogens, connect ECM to cell membranes

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13
Q

glycoproteins

A

bind plasma membrane to EC collagen and proteoglycans

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14
Q

collagenous fibers

A

(thickest) 25% of bodies protein; tough- resist stretching and tension

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15
Q

reticular fibers

A

(median thickness) thin collagen fibers with glycoprotein coat; form spongelike frameworks for spleen and lymph nodes

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16
Q

elastic fibers

A

(thinnest) made of elastin-coiled protein with ability to recoil (elasticity)

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17
Q

cell shapes

A

squamous, cuboidal, columnar, polygonal, stellate, spheroidal, discoid, fusiform, fibrous

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18
Q

cell junctions

A

physical connections between tissue cells;
types: tight junctions, desmosomes, and gap junctions

19
Q

tight junctions

A

integral membrane proteins of adjacent cells lock together to form an impermeable seal

20
Q

desmosomes

A

integral membrane proteins of adjacent cells interweave between cells and connect to intermediate filaments within cells; resist mechanical stress

21
Q

gap junctions

A

interlocked protein pores that allow substances to pass between cells

22
Q

(broad) types of epithelial tissue

A
  1. coverings and linings
  2. glands
23
Q

epithelial characteristics

A

polarity, specialized contacts, avascular, supported by connective tissue, innervated, regeneration

24
Q

structural characteristics of epithelium

A

cell shape, number of layers

25
epithelial functions
protection, secretion, excretion, absorption, filtration, sensation
26
simple squamous
bound by tight junctions function: rapid diffusion, secretion location: lung alveoli, kidney glomeruli, endothelium, serosa
27
simple cuboidal
function: absorption and secretion location: liver, thyroid, mammary, salivary, kidney tubules, bronchioles
28
simple columnar
function: absorption and secretion location: GI tract lining, uterus, kidneys, uterine tubes
29
pseudo-stratified columnar
includes cilia and goblet cells function: secretes and propels mucous location: upper respiratory tract, portions of male urethra
30
transport across epithelia
transcellular- osmosis, diffusion, active and vesicular transport paracellular- less common (due to tight junctions)
31
stratified squamous
most abundant epithelia, keratinized and non-keratinized
32
keratinized stratified squamous
function: resist abrasion and water loss location: epidermis
33
non-keratinized stratified squamous
function: resist abrasion location: tongue, oral mucosa, esophagus, vagina
34
stratified cuboidal
function: secretes sweat, sperm production, and ovarian hormone production location: sweat gland ducts, ovarian follicles, seminiferous tubules
35
transitional
function: distension location: ureter and bladder
36
glands
cell or organ that secretes or excretes substances
37
exocrine glands
maintain contact with body surfaces via ducts
38
endocrine glands
no ducts, secrete products into blood stream
39
goblet cells
GI and respiratory tracts; secrete mucous
40
types of exocrine glands
simple tubular, simple acinar, compound acinar, compound tubuloacinar
41
merocrine (eccrine)
products released as vesicles during exocytosis ie: tear glands, pancreas, gastric glands, sweat
42
apocrine
part of the cytoplasm broken off along with vesicles from apical portion ie: mammary glands
43
holocrine
cells accumulate product, then rupture to release it