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Flashcards in HIV/AIDS Deck (12)
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1
Q

gag is what?

A

Core proteins

2
Q

pol is what?

A

Reverse transcriptase

3
Q

p24 is what?

A

Core protein

Screening antibodies are mode to this protein

4
Q

gp120 is what?

A

Coat protein that binds to CD4

5
Q

Increase in transmission associated with uncircumcised males due to?

A

Increased presence of dendritic cells in the foreskin

6
Q

What does HIV virus require to get into host cell

A

Co-Receptor CCR5

7
Q

Where is CCR5 expressed?

A

Monocytes and lymphocytes

8
Q

CXCR4 is expressed where?

A

T-lymphocytes

9
Q

What do activated CD8 cells produce that blocks virus uptake?

A

Chemokines RANTES
MIP-1-a
MIP-1-b

10
Q

Apoptosis of uninfected memory CD4 lymphocytes in lymph nodes resulting from what?

A

TLR-7 and TLR-8

11
Q

What is a better predictor of progression than viral load?

A

CD38

12
Q

Where do M or T forms of HIV virus show up?

A

M form in early stages’

T form in late stages