Flashcards in HIV/AIDS Deck (12)
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1
gag is what?
Core proteins
2
pol is what?
Reverse transcriptase
3
p24 is what?
Core protein
Screening antibodies are mode to this protein
4
gp120 is what?
Coat protein that binds to CD4
5
Increase in transmission associated with uncircumcised males due to?
Increased presence of dendritic cells in the foreskin
6
What does HIV virus require to get into host cell
Co-Receptor CCR5
7
Where is CCR5 expressed?
Monocytes and lymphocytes
8
CXCR4 is expressed where?
T-lymphocytes
9
What do activated CD8 cells produce that blocks virus uptake?
Chemokines RANTES
MIP-1-a
MIP-1-b
10
Apoptosis of uninfected memory CD4 lymphocytes in lymph nodes resulting from what?
TLR-7 and TLR-8
11
What is a better predictor of progression than viral load?
CD38
12
