HIV/AIDS Flashcards Preview

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Flashcards in HIV/AIDS Deck (12):
1

gag is what?

Core proteins

2

pol is what?

Reverse transcriptase

3

p24 is what?

Core protein
Screening antibodies are mode to this protein

4

gp120 is what?

Coat protein that binds to CD4

5

Increase in transmission associated with uncircumcised males due to?

Increased presence of dendritic cells in the foreskin

6

What does HIV virus require to get into host cell

Co-Receptor CCR5

7

Where is CCR5 expressed?

Monocytes and lymphocytes

8

CXCR4 is expressed where?

T-lymphocytes

9

What do activated CD8 cells produce that blocks virus uptake?

Chemokines RANTES
MIP-1-a
MIP-1-b

10

Apoptosis of uninfected memory CD4 lymphocytes in lymph nodes resulting from what?

TLR-7 and TLR-8

11

What is a better predictor of progression than viral load?

CD38

12

Where do M or T forms of HIV virus show up?

M form in early stages'
T form in late stages