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Flashcards in HIV 1 and 2 Deck (57)
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1

What's prevalence?

#cases per population

2

What's incidence?

# cases per unit of time

3

What age range are new AIDS diagnoses in?

35-40

4

What is one cure for AIDS?

Bone marrow transplant using donor mutation

5

Where is the mutation that cures AIDS?

CCR5-delta32

6

Which fluids can transmit HIV?

Blood, semen, vaginal fluid, and breast milk

7

Is HIV diagnosis higher in males or females?

Males

8

Main cause of HIV transmission in males?

Male to male sexual contact

9

Main cause of HIV transmission in females?

Heterosexual contact

10

Which race has highest rate of HIV?

African Americans

11

Why is generation X of concern?

Optomistic in that they haven't seen themselves die of AIDs

12

What is the one cure for AIDs?

Mutation of CCR5 delta 32 from bone marrow donors with said mutation

13

Which fluids cannot transfer HIV/no cases reported?

Saliva, tears, sweat

14

Where does HIV survive in the environment?

It doesn't. Dries and dies

15

3 routes of infection for neonates?

1) Transplacental
2) Infected birth canal
3) Ingestion of breast milk

16

Risk of passing to child in infected untreated mother?

30%

17

Risk of passing to child in which mother and infant treated with HAART therapy?

18

Birth by C-section better or worse for transmission?

Better

19

Which genus of retroviruses is HIV related to?

Lentivirus

20

Difference between HIV 1 and 2?

HIV 2 less aggressive

21

Where would I find HIV 1?

US and Central Africa

22

Where would I find HIV 2?

India and West Africa

23

Function of Glycoprotein 120 (gp120)?

Mediates binding to CD4

24

Function of Glycoprotein 41 (gp41)?

Fusion to cell membranes

25

Lipids inside viral envelope are obtained from where?

Host cell

26

Where can I find the major capsid protein p24 of the HIV virus?

The core

27

What is the function of p24?

Diagnostic antibodies

28

Purpose of the nef accessory gene?

Inhibits apoptosis

29

Normal ratio of CD4 to CD8?

2:1

30

Ratio of CD4 to CD8 during AIDs?

1:2