Flashcards in Mycoplasma/Mycobacteria/Leprosy Deck (29)
Tiniest free-living organisms known?
Mycoplasma intra or extra cellular?
Main (2) disease Mycoplasma causes?
How does Mycoplasma pneumonia usually present?
What is Mycoplasma pneumonia associated with the production of?
What does "acid fast" mean?
Retains the red dye carbofuchsin after rinsing with acid solvents
Is Mycobacteria acid fast?
Virulence factors of mycobacteria?
Glycolipids that promote resistance to intracellular killing
Inhibit interferon activation of macrophages
Prevention of phase-lysosomal membrane fusion
Stimulate destructive cell mediated inflammatory injury
Histologic hallmark of Tuberculosis?
How is TB transmitted?
Hon focus found where?
Lower part of upper lobes or upper part of lower lobes unilaterally
How do most cases of TB pan out?
Fibrosis and calcification show up but rarely progress to disease
Best test for recent exposure?
BCG vaccine should not be considered responsible for PPD reaction of what size?
Atypical Mycobacterial infection that causes pulmonary disease?
M. avium intracellulare
M. avium intracellular associated with what disease?
What is Leprosy?
Obligate intracellular mycobacterium
How is leprosy spread?
Where is leprosy limited to?
Skin and nerves due to cool temp
Where does leprosy start?
Respiratory tract where it disseminates through blood to skin
Key feature of Leprosy?
Anesthesia of skin
What determines form of leprosy?
Degree of cell mediated immunity
Tuberculoid leprosy forms what?
Tuberculoid leprosy associated with strong what?
Tuberculoid leprosy mediated by what?
Release of IL-2 and IFN
Lepromatous leprosy associated with what?
Lack of TH-1 Helper response
Proliferation of organisms in macrophages
Is there granuloma formation in Lepromatous leprosy?
Lepromatous leprosy lesions filled with what?
Lipid laden macrophages containing many bacteria