Flashcards in Viral illness 4 Deck (46):
Herpes simplex virus 1 is what?
Herpes simplex virus 2 is what?
What does herpes simplex virus look like?
Large, encapsulated virus with ds DNA genome
Where does HSV remain latent?
What does HSV synthesize while in latent state?
What will you find if you scrape the lesion of HSV and look at it histologically?
Inclusion bearing multinucleate syncytial (giant cells)
Pattern of HSV lesion formation?
Bilaterally and ignoring dermatomes
Major cause of cornea blindness?
Fatal sporadic encephalitis caused by?
How is infectious mononucleosis transmitted?
Close contact, saliva by kissing
Where does Epstein Barr bind to to cause infectious mono?
Complement receptor on epithelial cells and B cells
Where does Epstein barr spread to?
Which cells on a smear appear atypical during an Epstein Barr virus infection?
What test do you use for Mono?
What is used in mono spot test?
Human anti-sheep RBCs agglutination
What will you see in blood of EBV patient?
Atypical lymphocytes (Anti-EBV T cells)
Biggest danger in EBV?
What is EBV common confused with?
Diagnosis of EBV dependent on what?
Positive heterophile reaction
Specific antibodies for EBV antigens
Are the heterophiles antibodies specific for EBV?
What causes X-linked lymphoproliferative disease?
Absence of gene called SAP (signaling lymphocyte activation molecule associated protein)
CMV is part of what important mnemonic?
In CMV what is important in diagnosis?
Urine sediment helps
CMV associated with what from latent infection of leukocytes>
Reactivation of viral infection
CMV infection in AIDs patients almost always accompanied by what infection?
How is HPV transmitted?
Non-neoplastic strains of HPV associated with what?
Neoplastic strains of HPV associated with what?
Viral intergration within the DNA
Verruca vulgaris is known as whaT?
Difference between condyloma accuminatum vs condyloma late?
Late are plaques from syphilis
Accuminatum are genital warts
Other Neoplastic viruses?
Only vector for Ebola?
How does Ebola spread?
Human to human
What is transmission for Ebola?
Where in the body does ebola hit?
Liver, viseral organ necrosis
How is Hanta virus spread?
Human through rodent urine or feces
How does Hanta virus present?
Acute hemorrhagic pulmonary syndrome
Where does Hanta virus present?
Southwest (4 corners area)
Where is Dengue?
Tropics and Africa
Which mosquito spreads Dengue?
Dengue hemorrhagic fever is also known as what?
Rare symptoms of Dengue?
Hemorrhagic phenomena, thrombocytopenia, dengue shock syndrome
How does West Nile Virus spread?
Transmitted by mosquitoes to birds and mammals
What is the major reservoir for West nile?
Humans are accidental
Who is at risk for West Nile?
Elderly and immunocompromised