Hypersensitivities

Question 1

Which type of reaction occurs when T-helpers stimulate B cells to produce IgE that sensitizes mast cells and basophils; requires repeated exposure to large doses of allergen?

Answer 1

Type 1 (IgE mediated)

Question 2

Which type of reaction is immediate, local (asthma), or systemic (anaphylactic: all over body)

Answer 2

Type 1 (IgE mediated)

Question 3

Involves destruction of a single cell; IgG or IgM antibodies bind to antigen on an individual’s own cells and destroys it.

Answer 3

Type 2 (Tissue-specific/ cytotoxic)

Question 4

Circulating antigen-antibody complexes accumulate in tissue, triggering the complement system’s inflammatory response.

Answer 4

Type 3 (Immune complex mediated)

Question 5

Cell-mediated (T-cells), not antibody-mediated; antigen presentation results in cytokine release, severe tissue injury, and fibrosis

Answer 5

Type 4 (cell-mediated/ delayed type)

Question 6

What type of hypersensitivity is an anaphylactic reaction?

Answer 6

Type 1

Question 7

Whic type of hypersensitivity is seen with a blood transfustion reaction?

Answer 7

Type 2

Question 8

Which hypersensitivity is seen with autoimmune conditions like lupud or COPD?

Answer 8

Type 3

Question 9

Which hypersensitivity is seen with contact dermatitis, TB skin tests, poison ivy, and a reaction to jewlery?

Answer 9

Type 4