Paget disease/OA and RA/Ankylosing spondylitis

Question 1

Progressive metabolic condition characterized by excessive bone destruction that occurs along with the replacement of bone by fibrous tissue and abnormal bone

Answer 1

Paget

Question 2

New bone is bigger but week; filled with new blood vessels

Answer 2

Paget

Question 3

Results in fragile, misshpaen bones

Answer 3

Paget

Question 4

Bone pain, skeletal deformities, fractures, warmth over affected bone, hypercalcemia

Answer 4

Paget

Question 5

Degenerative joint disease characterized by local deterioration of articulating cartilage and underlying bone as well as bony overgrowth

Answer 5

Osteoarthritis

Question 6

Not inflammatory in origin, but inflammation results from the tissue irritation

Answer 6

Osteoarthritis

Question 7

idiopathic/excessive mechanical stress on the joint

Answer 7

Osteoarthritis

Question 8

Joint pain/tenderness/stiffness/swelling, enlarged joints, limited ROM, hard nodules around the affected joint (bone spurs) Heberden’s and Bouchard’s nodes

Answer 8

Osteoarthritis

Question 9

Systemic autoimmune condition involving multiple joints

Answer 9

Rheumatoid arthritis

Question 10

Inflammatory process primarily affects the synovial membrane but can also affect other organs

Answer 10

RA

Question 11

joint pain, fatigue, low- grade fever, morning stiffness lasting more than 1 hour, warm/tender/stiff joints when not used, joint deformity (boutonniere and swan-neck)

Answer 11

RA

Question 12

Is there a cure for RA?

Answer 12

No

Question 13

Progressive inflammatory disorder affecting sacroiliac joints, intervertebral spaces, and costovertebral joints

Answer 13

Ankylosing spondylitis

Question 14

Inflammation starts in the vertebral joints of the lower back at the sacroiliac joints and progresses up the spine

Answer 14

Ankylosing spondylitis

Question 15

New bone forms in an attempt to remodel the inflammatory damage

Answer 15

Ankylosing spondylitis

Question 16

REsults in joint fibrosis and calcification

Answer 16

Ankylosing spondylitis

Question 17

Joints become ankylosed (fixed)

Answer 17

Ankylosing spondylitis

Question 18

Vertebrae appear square, and the vertebral column becomes rigid and loses curvature

Answer 18

Ankylosing spondylitis

Question 19

Genetic seems to play a role in development (HLA-B27 gene is present in most cases)

Answer 19

Ankylosing spondylitis

Question 20

Intermittent lower back pain (early), pain, stiffness, lower back pain

Answer 20

Ankylosing spondylitis