Flashcards in ID - Endocarditis Deck (12):
How many of the Duke criteria must be met to Dx infective endocarditis?
2 major OR 1 major + 3 minor OR 5 minor
What are the 2 major Duke criteria?
1. 2 positive blood cultures for typical IE organisms
2. Abnormal echo
What are typical IE organisms?
S. aureus; Strep. viridans, bovis, enterococci; Gram(-) rods; Candida; or HACEK organisms
What are the HACEK organisms?
What are echo findings indicative of IE (3)?
Intracardiac mass/vegetation, abscess, or new prosthetic valve dehiscence/regurg
What are the 5 minor Duke criteria?
2. Risk factors
3. Vascular findings
4. Immunological findings
5. Blood culture (+) not meeting major criteria
What are the immunologic findings in IE?
Roth spots, Osler's nodes, or glomerulonephritis
What are Osler's nodes?
Painful, pea-shaped lesions
What is the best empiric Tx for IE?
Vanc + Gentamicin x 4-6 wks.
Which cardiac defects require IE ppx before certain procedures?
Prosthetic valves, unrepaired cyanosic heart dz, previous IE, and transplant recipients w/ valve dz
Which procedures require antibiotic ppx for IE?
Dental procedures that cause bleeding, respi tract surgery, and surgery of infected skin