Flashcards in Immunology Deck (41):
1
Common variable immunodeficiency
Defect in B cell differentiation
2
paracortex of LN which cells
T cells
3
what corelate with ESR
fibrinogen
4
which (complement component) def in paroxysmal N. hemoglobuniuria
DAF
5
C3 vs. C5b-9 def
C3 capulated and next, MAC, neisseria
6
which IL is osteoclast activating factor
IL-1 (cause fever)
7
what cytokine mediate septic shock
TNF
8
passive immunity (To Be Healed Very Rapidly)
Tetanus Botulinum, HBV Varicella Rabies
9
Killed vaccines
RIP Always
rabies
injectable influenza
Polio (salK)
HAV
10
tryptase
to diagnose type 1 HS (late response because of leukotreins)
11
ABO incompatibility whcih HS
type II
12
Type III eg
serum sickness and arthus
SLE
PAN
PSGN
13
type I blood trasfustion reaction Rx
allergy: antihistamine
Anaphylatic: epinephrine
14
type II blood trasfustion reaction
non-hemolytic: to donor HLA and WBC
hemolytic: ABO incompatiility (chest pain back pain)
15
Anti-centromere ab
CREST (limited scleroderma)
Anti-Scl70 for scleroderma (diffuse)
16
Anti-mitochondrial ab
1 biliary cirrhosis
17
anti-smooth musle ab
autoimmune hepatitis
18
c ANCA
wegners
19
immunodeficiencies:B
X-linked (bruton's agamm...), seltive IgA def, CVID
20
immunodeficiencies:T
Digeorge, IL-12R def, Job Syn, c/c mucocuta...candid
21
immunodeficiencies:T&B
SCID ataxi telengectasia, Hyper IgM syndrom, WAS
22
immunodeficiencies:phagocyte
LAD 1 (CD18), Chediak-higashi and CGD
23
cause of job syndrome
lack of Th17 due to stat3 mutations
24
common cause of SCID
IL-2R def
25
immunodeficiency with lymphoid hyperplasia
hyperIgM syndrome (defcetive CD40L)
26
Wiskot AS: CF
WATER:
thrombocytopenic purpura
Ecsema
Recurrent infections
rememeber increased IgA and E
27
delayed spearation of cord
LAD1 (CD18)
28
partical oculocuaneous albinism
chediak...
29
NBT test neg immunodefecincty
CGD
30
single word patholoies of transplant reaction
hyperacute: thrombosis (type II)
acute: lymphocytic infiltrate
c/c interstitial fibrosis/fibrous intimal thickening
31
toxicity of calcieurin inhibitors
nephrotoxic (can combine with rapamycin: no nephrotoxic)
32
SE of cyclosporine vs tacroimus
former gingival hyperplasia and hirsuitism
33
oprelvekin
recombinant IL-11 for thrombocytepnia
34
therapeutic antibodies: VEGF
bevacizumab and ranizumab (bevan and rani)
35
therapeutic antibodies: alemtuzumab
CD52 (for lym...rhyme)
36
therapeutic antibodies: rituximab
CD20 (20 year old rita)
37
therapeutic antibodies" Trastuzumab
TWO: her2/neu
38
therapeutic antibodies: TNFa
infliximab and adalimumab
39
p199. two things found in splenectomy
howell jolly bodies (nuclear remnants) and target cells
40
p207.aldesleukin
IL-2 for metastatic mellanoma and RCC
41