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Flashcards in Immunology Deck (41):
1

Common variable immunodeficiency

Defect in B cell differentiation

2

paracortex of LN which cells

T cells

3

what corelate with ESR

fibrinogen

4

which (complement component) def in paroxysmal N. hemoglobuniuria

DAF

5

C3 vs. C5b-9 def

C3 capulated and next, MAC, neisseria

6

which IL is osteoclast activating factor

IL-1 (cause fever)

7

what cytokine mediate septic shock

TNF

8

passive immunity (To Be Healed Very Rapidly)

Tetanus Botulinum, HBV Varicella Rabies

9

Killed vaccines

RIP Always
rabies
injectable influenza
Polio (salK)
HAV

10

tryptase

to diagnose type 1 HS (late response because of leukotreins)

11

ABO incompatibility whcih HS

type II

12

Type III eg

serum sickness and arthus
SLE
PAN
PSGN

13

type I blood trasfustion reaction Rx

allergy: antihistamine
Anaphylatic: epinephrine

14

type II blood trasfustion reaction

non-hemolytic: to donor HLA and WBC
hemolytic: ABO incompatiility (chest pain back pain)

15

Anti-centromere ab

CREST (limited scleroderma)
Anti-Scl70 for scleroderma (diffuse)

16

Anti-mitochondrial ab

1 biliary cirrhosis

17

anti-smooth musle ab

autoimmune hepatitis

18

c ANCA

wegners

19

immunodeficiencies:B

X-linked (bruton's agamm...), seltive IgA def, CVID

20

immunodeficiencies:T

Digeorge, IL-12R def, Job Syn, c/c mucocuta...candid

21

immunodeficiencies:T&B

SCID ataxi telengectasia, Hyper IgM syndrom, WAS

22

immunodeficiencies:phagocyte

LAD 1 (CD18), Chediak-higashi and CGD

23

cause of job syndrome

lack of Th17 due to stat3 mutations

24

common cause of SCID

IL-2R def

25

immunodeficiency with lymphoid hyperplasia

hyperIgM syndrome (defcetive CD40L)

26

Wiskot AS: CF

WATER:
thrombocytopenic purpura
Ecsema
Recurrent infections
rememeber increased IgA and E

27

delayed spearation of cord

LAD1 (CD18)

28

partical oculocuaneous albinism

chediak...

29

NBT test neg immunodefecincty

CGD

30

single word patholoies of transplant reaction

hyperacute: thrombosis (type II)
acute: lymphocytic infiltrate
c/c interstitial fibrosis/fibrous intimal thickening

31

toxicity of calcieurin inhibitors

nephrotoxic (can combine with rapamycin: no nephrotoxic)

32

SE of cyclosporine vs tacroimus

former gingival hyperplasia and hirsuitism

33

oprelvekin

recombinant IL-11 for thrombocytepnia

34

therapeutic antibodies: VEGF

bevacizumab and ranizumab (bevan and rani)

35

therapeutic antibodies: alemtuzumab

CD52 (for lym...rhyme)

36

therapeutic antibodies: rituximab

CD20 (20 year old rita)

37

therapeutic antibodies" Trastuzumab

TWO: her2/neu

38

therapeutic antibodies: TNFa

infliximab and adalimumab

39

p199. two things found in splenectomy

howell jolly bodies (nuclear remnants) and target cells

40

p207.aldesleukin

IL-2 for metastatic mellanoma and RCC

41

p211. Indirect Coombs test

test Rh- woman for Rh+ antibodies