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Flashcards in Musculo skeletal Deck (214):
1

code for wrist bones

so long to pinky, here comes the thumb

2

hook of hamate nerve

ulnar

3

carpal tunnel syndrome

median nerve

4

superficial laceration of palm N

recurrent branch of median nerve

5

klumpke paralysis

claw hand

6

Golgi tendon organ and muscle spindle: sensitive to

GTO to tension and spindle to length

7

which channel in sm and cardiac muscle for entry of extracellular ca++

voltage gated L-type

8

AHM is

myosin and dark

9

IZ (sarcomere) is

actin

10

anti-cyclic citrullinated peptide antibody associated with

RA

11

uricosuric drugs

probenecid and sulfinpyrazone

12

Ab specific for SLE

dsDNA and smith

13

anti-histone antibodies specific for

drug induced SLE (hydralazine and procainamide)

14

gomori trichrome stain

mitochondrial myopathy (red ragged fiber disease)

15

myasthenia gravis HS type

II

16

Ach E inhibitors (edrophonium test)

improves M. gravis

17

Lambert Eaton syndrome associated with

small cell lung cancer

18

desmacula made up of

keratin (desmosome/macula adherens)

19

celecoxib

selective COX-2 inhibitor

20

Montelukast inhibit

LTC4, D4, E4

21

PABA blocks

UVB

22

artery with radial N in the groove

deep brachial A

23

drugs for restless leg syndrome

dopamine agonists (ropinirole, pramipexole)

24

Hip extensors

G. maximus, semitendinosus, semimembranosus, long head of b. femoris

25

anterior drawer sign tests for

ACL

26

sensation of lateral forarm

musculo skeletal

27

guyon's canal which nerve

ulnar

28

winged scapula which N and M

long thoracic and S. anterior

29

pope's blessings

pop for proximal median nerve

30

foot drop

common peroneal nerve

31

surgical neck of humerus which A and N

axillary N and posterior circumflex A

32

type I muscles are

postural

33

marble bone disease

osteopetrosis

34

mutation in achondroplasia

FGFR1

35

brown tumor is aka

osteitis fibrosa cystica

36

soap bubble x ray

giant cell tumor

37

onion skin x ray

ewings

38

night pain bone tumor

osteoid osteoma

39

two interesting lab findings in sarcoidosis

hypercalcemia due to high vitamin D
increased ACE

40

anti-centromere antibody

CREST c for c

41

structural support via keratin (cellular connections)

desmosome

42

stuck on appearance

SK pottekad

43

keratin pearl seen in

squamous cell ca

44

S100 tumour marker

melanoma

45

pallisading nuclei which skin ca

basal

46

increased anterior gliding

ACL injury

47

Mc murray test popping on external rotation

medial meniscal tear

48

unhappy triad

MAM (MCL,ACL,medial meniscus)

49

most common rotator cuff injury and how to test

supraspinastus and empty can

50

pitching injury

infraspinatus

51

acutecarpal tunnel syndrome

dislocation of lunate

52

wrist bone and ulnar nerve injury

hook of hamate

53

guyan canal syndrome

ulnar nerve in cyclist

54

axillary nerve when injury

surgical neck, anterior dislocation

55

musculucutaneous nerve supplies

biceps and lateral forearm

56

confusion in radial N injury

decreased grip

57

supracondylar fracture of humerus

median N

58

distal median nerve lesion

sensation intact

59

distal injury of median adn ulnar

median- carpal tunnel, lunate
dislocation and laceration
ulnar- guyon canal, hamate

60

klumpke which trunk and imp muscle

lower, lumbricals (claw hand)

61

thoraxic outlet sydnrome same as

klumpke

62

sara's long

wings

63

proximal lesions are seen when

making fist

64

for claw hand, think about

lumbricals only

65

obturator nerve supplies

adductor compartment (pelvic surgery)

66

femoral N

thigh flexion and by extension (pelvic fracture)

67

tibial N conditions

bakers cyst, tarsal tunnel syndrome

68

gluteal injections

upper medial- superior gluteal
lower medial- sciatic nerve

69

trendlenburg droop

damaged nerve is opposite side

70

inf gluteal nerve injury

posterior hip dislocation
difficulty to climb stairs
glutues maximus 9extension hip)

71

sciatica commonly involves

L5,S1

72

disc levels

L5,S1- achilles
L3,L4- knee
L4-L5- dorsiflexion

73

long thoraxic N go with

lateral thoraxic artery (L and L)

74

axillary nerve go with

posterior circumflex art

75

radial N go with

deep brachial art

76

cubitus fossa median N go with

brachial art

77

popliteal fossa tibial n go with

popliteal art

78

medial malleolustibial N with

posterior tibial art

79

GTO vs muscle spindle

tension vs length (reflexes)

80

L type Ca+channels present in

all 3 tissues

81

key event before SR calcium release

depolarisation of DHP receptor on t tubule

82

ryanodine receptor present in

reticulum sarcoplasmic (R for R)

83

HIZ

shrinkage, A always same length

84

thin filament has

tropomyosin and actin

85

when myosin detach from actin

when new ATP is bound- locked
(on power stroke, release ADP and Po4)

86

AHM is

dark, myosin (Z is darkest)

87

in skeletal muscle, one t tubule has

2 terminal cistern (triad)

88

1 slow red ox

postural muscle

89

smooth muscle contraction

ca- calmodulin complex- myosin light chain kinase
cGMP- M.L.C phospahte

90

endochondral calcification

cartilage - woven- lamellar

91

woven bone seen in adults

pagets disease and fractures

92

estrogen and bone

biased apoptosis

93

osteoporosis which bone

trabucular, spongy, cancellous

94

denosumab

RANKL

95

priamry osteoporosis levels

ca,po4,PTH normal

96

osteopetrosin which cell

osteoclast (needs acid)

97

osteomalacia which bone

osteoid (blasts are involved)

98

osteitis deformans (pagets) levels

all normal

99

paget histology

mosaic of woven and lamellar
cement lines

100

paget types and risk

LMS and osteogenic sarcome and heart failure (V sunt)

101

avascualr necrosis of femoral head art

medial circumflex femoral

102

legg carve perthe disease

think leg
femoral head necrosis in children

103

night time pain

osteoid osteoma

104

giant cell tumor aka and x ray

osteoclastoma, soap bubble, epiphysis benign tumor, aggressive

105

osteochondroma

chondroid cap

106

codeman triangle and sunburst

osteosarcoma

107

onion skin and diaphysis

ewing sarcoma (11:22)

108

pannus and fibrinoid necrosis seen in

RA

109

specific test fro RA

anti-CCP 9Cyclic citrulinated)

110

treatment for RA

methotrexate

111

rhooma never

DIPs

112

sjogren syndrome, antibody adn risk

anti Ro, LA, MALT

113

excretion or production gout

excretion problem (alcohol competition)

114

DOC for gout

allopurinol

115

uricosuric drugs are given only

in excretion problem (not production)
stone risk

116

pseudogout

calcium pyrophosphate, rhomboid

117

in acute attack of gout CI

probenacid and allopurinol

118

bone secondaries

blastic (sclerotic)- prostate, hodgkins lymphomanand small cell (HSP)
Mixed GIT and breast

119

sausage fingers adn pencil in cup

psoriatic arthritis

120

additional findings in ankylosing spondylitis

uveitis and AR

121

reiter syndrome triad

conjunctivitis, urethritis, arthritis
chlamydia infection

122

location of osteomyelitis

metaphysis

123

blood picture in SLE

pancytopenia

124

SLE kidney

nephritic- DPGN
nephrotic- MGN

125

cause of death in SLE

heart

126

anti dsDNA and anti smith

poor prognsis and snRNP

127

3 drugs for SLE

hydralazine, procainamide, isoniazide

128

clotting test in antiphospholipid

increased PTT (VDRL +)

129

ACE levels and sarcoidosis

elevated

130

treatment for sarcoidosis

steroids

131

polymyalgia rheumatica adn CK

normal (muscle unaltered)

132

association of mitochondrial myopathies

myoclonic epilepsy, optic neuropathy, lactic acidosis adn stroke

133

sir jomi

poly and dermatomyositis
SRP,Jo and Mi
Jo= anti histydyl and RNA synthetase

134

skin is peri foural

dermatomyositis, perimyseal, inflammation and CD4 cells

135

skin in dermatomyositis

gottron papules, periorbital rash, shawl and face rash

136

risk of dermatomyositis

occult malignacny

137

proximal muscle weakness

lambert eaton synrome

138

edrophonium and MG

improves

139

digital pitting

scleroderma

140

cause of death in scleroderma

pulmonary vessel involvement (CD4 cells)

141

diffuse scleroderma antibody

Scl- 70 (DNA topoisomerase 1)
CREST_ anticentromere

142

desmosomes are seen in

spinosum

143

californians like

girls in string bikini

144

tight AK gap

A for adherance and actin adn adherin
k for desmakula

145

integrins bind to

CFL of absement membrane
collagen, fibronectin and laminin

146

parakeratosis

nucleus in corneum- psoriasis

147

acantholysis

P vulgaris

148

acanthosis

increased spinosum- nigricans and psoriasis
granulosum low in psoriasis

149

spongiosis-

eczema, edema

150

albinism mechanism

melanocyte dont make melanin
decreased tyrosinase activity

151

atopic dermatitis site

cheek, cubital fossa

152

intradermal naevi

papular (no pigment)

153

junctional neavi

flat macules (pigment +)
compound papule+. pigment +

154

munro abscess and psoriasis

psoriasis

155

rhinophyma

bullous malformation of nose in rosaea (no comedones)

156

leser trelat sign

lot of SK in malignancy

157

Urushiol

hapten in poison ivy (linear streak)

158

honey colored crusting

impetigo (both bacteria)

159

erisipelas

s pyogenes

160

abscess

aureus

161

purple colored skin

necrotizing fascitis

162

SSSS and TEN

TEN in junction (SSSS granulosum)

163

Hairy leukoplakia virus

EBV

164

antibody to desmoglein

vulgaris

165

bullous pemphigoid

strong (nikolsky negative, tense blister)

166

vulgaris- oral mucosa

involved

167

dermatitis herpetiformis which antibody

IgA

168

target lesion in skin

E multiforme

169

more than 10%

TEN

170

SJS vs multiforme

2 mucosal membranes involved in SJS

171

A nigricans

HYPERINSULINEMIA AND malignancy

172

AK is limited and risk

epidermis adn SCC (excessive sun)

173

lichen planus histology

saw tooth infiltrate of lymphocytes at teh junction

174

lichen planus is associated with

Hep C

175

herald patch and x mas tree

p rosea (self resolving)

176

sunburn B for

UVB

177

BSC histology

paliseding nuclei (keratin pearl for SCC)

178

keratacanthoma

SCC that regress

179

skin cancer with chronic draining sinuses

SCC

180

intracranial Hge skin cancer

melanoma

181

melanoma gene

activating BRAF (vemurafenib)

182

membrane phospholipids becomes arachdonic acid by

phospholipase A2 (steroids inhibit)

183

Zileuton vs lukast

5 lipooxygenase inhibitor (synthesis zileuton)
leukotriene receptor antagonsit

184

cyclic endoperoxidase same as

PGlandins

185

PGI2

decrease vascular tone, decrease aggregation

186

acetaminophen toxicity

hepatic necrosis (NAPQ1 deplets glutathione)

187

N acetylcysteine function

regenerates glutathione

188

SE of aspirin

tinnitus

189

test for aspirin toxicity

ferric chloride test for phenol

190

mechanism of aspirin poisoning

inhibit TCA cycle (1st tachypnea)

191

celecoxib risk

decrease PGI2,ie aggregation
no effect on TXA2 and platelets

192

why renal ischemia in NSAIDS

PG dilate afferent

193

bisphosphonates are

pyrophosphates analog
bind to hydroxy apatite
inhibit osteoclast

194

SE of bisphosphonate

corrosive esophagitis
osteonecrosis of jaw

195

teri-para-tide

PTH analog, increase blast activity

196

psoriasis and topical vitamin D

keratinocyte proliferation less
differentiation more

197

febuxostat

XO inhibitor

198

uricosuric drug

probenecid, sulfinpyrazone

199

colchizine MOA similar to

vincristine/blastine

200

salicylates are CI in

acute gout (reduces UA clearance)

201

TNF a drug

etanercept, infliximab, adalimumab

202

restless leg syndrome treatment

ropinirole (dopamine agonist)
go for a roll

203

glans penis and skin on posterior calf drains to

deep inguinal

204

PTH first stimulate

blast which RANK L and M CSF to stimulate clasts

205

radial head subluxation damage

deep branch of radial nerve (no sensory defect)

206

N going through P major

femoral N

207

Kal madangi

anterior talo fibular ligament
which is a lateral ligament

208

piriformis divide

greater scaitic foramen above superior gluteal N
below inferior and sciatic

209

greater and lesser s foramen

sacrospinous ligament

210

posterior cruciate ligament start

medial condyle of femur (MP)

211

spasmodic torticollis is a type of

focal dystonia

212

appendectomy N

iliohypogastric N

213

interscalene N block risk

phrenic N

214

dislocation of tibia

anterior and posterior
popliteal art