Flashcards in Renal Deck (189)
Loading flashcards...
1
donor renal A and V anastamosed to
external iliac A and V
2
hartnup disease mech
neutral aminoacidura (also decreased absorption by enterocytes) eg. tryptophan
3
tryptophan gives rise to
nicotinic acid, serotonin, melatonin
4
Fanconi syndrome mech
generalized reabsorptive defect in PCT (involves all AA)
5
Thin descending and thick ascending loop of Henle (water and solutes)
descending permeable to water but not solutes : ascending permeable to solutes but not water
6
In nephon, all glucose and AA absorbed in
PCT
7
In nephon, most dilute urine in
DCT
8
ADH action on nephron and which cell
principal cell, V2 receptor, more aquaporins on the membrane (water hormone)
9
aldosterone on nephron, which cell
Principal cell (Na+ & water reabsorption, K+ secretion)
a-intercalated cell (K+ absorption; H+ secretion)
10
Juxta glomerular cells on
Afferent arteriole (secrete renin)
11
macula densa on
DCT (sense NaCl)
12
trigger for renin secretion
decrease renal arterial pressure and increased renal sympathetic discharge (beta 1)
13
erythropoetin secreted by
interstitial cells in the peritubular capillary bed
14
primary disturbance in metabolic A/A
HCO3
15
Primary disturbance in respiratory A/A is
pCO2
16
All (pCO2, HCO3 and pH) decreased in
metabolic acidosis
17
IF of PSGN two terms
starry sky or lumpy-bumpy
18
what deposits in PSGN
IgG, IgM and C3 (note: type III)
19
crescentic GN
RPGN
20
Goodpasture syndrome leads to what type of GN
RPGN
21
two types of pauci immune RPGN
wegners G and microscopic polyangitis
22
what type of HS in Goodpastures syndrome
type II
23
what type of GN SLE leads to
DPGN (membranous nephropathy is the nephrotic version of SLE)
24
race and nephrotic syndrome
FSG Sclerosis (african american and hispanic)
membranous nephropathy (caucasian)
25
urease + bugs cause what type of stone
AMP, struvite, staghorn (due to alkalinization of urine)
26
clear cell ca originate from
PCT
27
eosinophiluria with rash
drug induced interstitial nephritis
28
acetazolamide MOA
Carbonic anhydrase inhibitor (NaHCO3 diuresis)
29
loop diuretic MOA
inhibit Na+/K+/2Cl- cotransporter of thick ascending LOH
30
