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Flashcards in Renal Deck (189)
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1

donor renal A and V anastamosed to

external iliac A and V

2

hartnup disease mech

neutral aminoacidura (also decreased absorption by enterocytes) eg. tryptophan

3

tryptophan gives rise to

nicotinic acid, serotonin, melatonin

4

Fanconi syndrome mech

generalized reabsorptive defect in PCT (involves all AA)

5

Thin descending and thick ascending loop of Henle (water and solutes)

descending permeable to water but not solutes : ascending permeable to solutes but not water

6

In nephon, all glucose and AA absorbed in

PCT

7

In nephon, most dilute urine in

DCT

8

ADH action on nephron and which cell

principal cell, V2 receptor, more aquaporins on the membrane (water hormone)

9

aldosterone on nephron, which cell

Principal cell (Na+ & water reabsorption, K+ secretion)
a-intercalated cell (K+ absorption; H+ secretion)

10

Juxta glomerular cells on

Afferent arteriole (secrete renin)

11

macula densa on

DCT (sense NaCl)

12

trigger for renin secretion

decrease renal arterial pressure and increased renal sympathetic discharge (beta 1)

13

erythropoetin secreted by

interstitial cells in the peritubular capillary bed

14

primary disturbance in metabolic A/A

HCO3

15

Primary disturbance in respiratory A/A is

pCO2

16

All (pCO2, HCO3 and pH) decreased in

metabolic acidosis

17

IF of PSGN two terms

starry sky or lumpy-bumpy

18

what deposits in PSGN

IgG, IgM and C3 (note: type III)

19

crescentic GN

RPGN

20

Goodpasture syndrome leads to what type of GN

RPGN

21

two types of pauci immune RPGN

wegners G and microscopic polyangitis

22

what type of HS in Goodpastures syndrome

type II

23

what type of GN SLE leads to

DPGN (membranous nephropathy is the nephrotic version of SLE)

24

race and nephrotic syndrome

FSG Sclerosis (african american and hispanic)
membranous nephropathy (caucasian)

25

urease + bugs cause what type of stone

AMP, struvite, staghorn (due to alkalinization of urine)

26

clear cell ca originate from

PCT

27

eosinophiluria with rash

drug induced interstitial nephritis

28

acetazolamide MOA

Carbonic anhydrase inhibitor (NaHCO3 diuresis)

29

loop diuretic MOA

inhibit Na+/K+/2Cl- cotransporter of thick ascending LOH

30

what drug inhibits loop diuretics fn

NSAIDS