Flashcards in Jitt # 5 Case # 8 MHC Class II Deficiency Deck (8):
MHC II presents antigens to which type of T-Cell
What type of peptides do MHC II molecules express? Meaning, what type of pathogens are involved in MHC II expression?
Extracellular pathogens or proteins, or pathogens that persist intracellularly inside vesicles
What type of cells are MHC II molecules expressed on?
APCs; DC, macrophages, B lymphocytes, activated T-cells, activated epithelial cells, activated thymus * activated by interferon gama
What type of cytokine upregulates the expression of MHC II molecules?
What are the three classes of MHC II molecules?
DP, DQ, DR
MHC II Deficiency
Low Ig levels; deficiency of CD4+ Cells Lack HLA-DR; autosomal recessive trait;