Flashcards in Jitt # 9 Quiz Deck (6):
Which cytokine produced early in the response favors the development of a T helper effector cell poised to combat intracellular bacterial infections?
IL-12 also IFNg
Which cytokine might be beneficial to a patient with lepromatous leprosy?
Why would patients with lepromatous leprosy such as Ursula be prone to asthma?
Because in cases of lepromatous leprosy there is defective Th1 cell responses but on the other hand Th2 responses predominates and this lead to vigorous but ineffective antibody response against M. leprae. The Th2 response activates IgE and eosinophils which make a patient more prone to ashtma. IgE activates mast cells and eosinophils through binding of IgE receptors and induce inflammatory mediators such as histamine and cytokines.
You suspect a patient has infectious mononucleosis in the acute phase. Which type of antibody would you test for in the serum of the patient?
IgM and IgG antibodies to viral capsid antigen
Would you predict that these antibodies would be protective? In other words, do antibodies to any of the viral antigens help clear the virus?