Jitt # 6 Questions And Answers Flashcards Preview

Medical Immunology Bios 443/843 > Jitt # 6 Questions And Answers > Flashcards

Flashcards in Jitt # 6 Questions And Answers Deck (8):
1

The thymic equivalent of the bone marrow stromal cells are the thymic

epithelial cells

2

Double positive thymocytes express

both CD4 and CD8

3

The “surrogate light” chain that is expressed with newly rearranged β chain

is pTα chain

4

Single positive T cells

are either mature Th or mature Tc cells

5

To give nude mice a normal immune system one would have to

transplant a thymus

6

The term MHC restriction refers to the:

requirement for antigen to be recognized in association with MHC molecules

7

Double positive T cells with a transgenic TCR specific for HY (male) antigen on self Class I MHC

would develop into CD8+ T cells in female mice but it would not develop into mature T cells in male mice

8

Positive and negative selection of T cells

must involve signals that differ either in amount or in type

Decks in Medical Immunology Bios 443/843 Class (56):