Jitt # 6 Questions And Answers Flashcards Preview

Medical Immunology Bios 443/843 > Jitt # 6 Questions And Answers > Flashcards

Flashcards in Jitt # 6 Questions And Answers Deck (8):

The thymic equivalent of the bone marrow stromal cells are the thymic

epithelial cells


Double positive thymocytes express

both CD4 and CD8


The “surrogate light” chain that is expressed with newly rearranged β chain

is pTα chain


Single positive T cells

are either mature Th or mature Tc cells


To give nude mice a normal immune system one would have to

transplant a thymus


The term MHC restriction refers to the:

requirement for antigen to be recognized in association with MHC molecules


Double positive T cells with a transgenic TCR specific for HY (male) antigen on self Class I MHC

would develop into CD8+ T cells in female mice but it would not develop into mature T cells in male mice


Positive and negative selection of T cells

must involve signals that differ either in amount or in type

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