Lecture 14 Flashcards

(31 cards)

1
Q

Define:

Alpha motor neuron

A

A neuron innervating power producing extrafusal muscle fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe:

Alpha motor neurons

(4 points)

A
  • Axons innervate extrafusal muscle fibers
  • Axons are much bigger, have quicker conduction times
  • Larger than gamma motor neurons
  • Innervate numerous extrafusal muscle fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the difference between intrafusal and extrafusal muscle fibers?

A

Intrafusal muscle fibers lie inside extrafusal muscle fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the function of an intrafusal muscle fiber?

A

Detects stretching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are intrafusal muscle fibers also known as?

A

Muscle spindle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe:

Gamma motor neurons

A
  • Wraps around center of intrafusal muscle fiber
  • Sends information back to central nervous system
  • Synapse with alpha motor neuron to coordinate contractions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where does information from the gamma motor neuron enter and exit?

A

Enter at the back of the spinal cord via the dorsal root - specifically the dorsal root ganglion
Leaves the central nervous system via the ventral root ganglion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does the sensitivity of the intrafusal muscle fibers depend on?

A

Fusimotor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are fusimotor neurons also known as?

A

Gamma motor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the result of increased fusimotor drive?

A

Any small stretch in the intrafusal muscle fibers can be controlled via contraction of extrafusal muscle fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Define:

Motor Unit

A

Alpha motor neurons and all the muscle fibers it innervates; a unit of force production within the CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

True or False:

Motor units are smaller than gamma motor neurons

A

False, motor units are much larger than gamma motor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What changes in motor units depending on the type of muscle that they are innervating?

A

Innervation ratio changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does innervation ratio depend on?

A

Dependent on the muscle and how precise the muscle has to be

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

True or False:

Higher innervation ratio allows for more precise motor control

A

False, low innervation ratio allows for more precise motor control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Define:

Gamma motor neuron

A

Small neurons innervating intrafusal muscle fibers

17
Q

Describe:

Gamma motor neurons

A
  • Determines sensitivity of intrafusal muscle fibers to stretch
  • Smaller than alpha motor neurons
  • Oriented in parallel to extrafusal muscle fibers
18
Q

What type of connections do gamma motor neurons form?

A

Polar-to-polar connections

19
Q

Define:

Polar-to-polar connections in gamma motor neurons

A

Connection to bone a and bone b along with its structure makes it optimally designed in order to detect stretch

20
Q

List:

3 types of extrafusal muscle fibers

A
  1. Fast twitch, fatigable (FF) (Fast Motor Unit)
  2. Fast twitch, fatigue resistant (FR)
  3. Slow twitch, fatigue resistant (SR) (Slow Motor Unit)
21
Q

Describe:

Fast twich, fatigable (FF) (Fast Motor Unit)

A
  • Characterized by highest conduction velocity (100 m/s)
  • Large fiber diameter
  • Innervate fast twitch muscle fibers (Type II)
  • Produce lots of force, uses anaerobic glycolysis
22
Q

Describe:

Fast twitch, fatigue resistant (FR)

A
  • Characterized by medium conduction velocity (60 m/s)
  • Medium fiber diameter
  • Innervate fast and/or slow twitch muscle fibers
23
Q

Describe:

Slow twitch, fatigue resistant (SR) (Slow Motor Unit)

A
  • Characterized by slow conduction velocity (40 m/s)
  • Small fiber diameter
  • Innervate slow twitch muscle fibers (Type I)
  • Slow oxidative, uses aerobic glycolysis
  • Creates sustained force over time
24
Q

How do we read a muscle biopsy cross section?

A

Darkest colour is type I slow oxidative muscle type
Lightest colour is a fast twitch motor unit

25
Why are slow oxidative muscle types darkest in colour on a muscle biopsy cross section?
As it is oxidative, it requires hemoglobin making it darker in color
26
In a person with spinal cord injuries, what is percent composition of fast and slow motor units?
96% fast 4% slow
27
Why do people with spinal injuries have such a high percentage of fast motor units?
They have limited motion, thus they only require fast motor units
28
# Describe: Henneman Size Principle
Size of motor units increase with size of force production * Less force = only slow motor units are used * More force = fast motor units start to be used
29
How are motor units clinically relative? Explain
Falls in older adults * Individuals 30 years onward lost ~1%/year of total number of motor units with more rapid decrease after 60 * Older adults exhibit selective loss of fast motor units, which is vital for regaining balance is best done with fast motor units as it is fast-twitch
30
What happens to motor units and muscle fibers with older adults?
* Large diameter motor units exhibit signs of demyelination and thus reduced conduction times * Efficacy of muscle fiber, along with size of muscle fiber changes
31
How are intrafusal and fast twitch muscles trained in older people?
Exercises such as wobble board and grid exercises