Flashcards in Lecture 9 Deck (62)
Pathogens that produce disease both inside and outside the GIT
E.coli and Salmonella
Pathogens that cause disease only inside GIT
Shigella,Vibrio, Campyobacter, H pylori
Pathogens present in GIT but cause disease only outside
Kebsiella group, Pseudomonas, Bacteroids
G- rods belong to what family?
enterobacteriacea- primarily in colon of humans and animals as normal flora
Do gram - rods rely on oxygen?
all are facultative anaerobes except pseudomonas which is an obligate aerobe
What do Gram - rods have on their cell wall?
What does E.coli cause?
Urinary trac infections, travelers diarrhea and neonatal sepsis
Where is E.coli normal flora found?
in colon and feces
How do Gram - move?
move with single flagellum and plenty of pili
Pathogenicity of E.coli
adheres to mucous membranes of jejunum and ilium by pili causes intestinal, systemic and urinary infections- some strains cause watery diarrhea and some cause bloody diarrhea
What is the most frequent nasocomial infection?
UTI- due to indwelling catheters
What other type of infection can E.coli cause from UTI?
infection of bladder known as cystitis- pyelonephritis can occur if infection goes further up
Symptoms of bladder infections
frequent urination along with feeling of need to urinate, nocturne, pain in pubic area, hematuria
Symptoms of Urethritis
discomfort, irritation or pain at urethral meatus or burning sensation on urination, pyuria, pyrexia, cloudy and foul urine
Symptoms of kidney infection
symptoms from urethritis as well as emesis, back/side pain, abdominal pain, high spiking fever, night sweats and fatigue
What E.coli looks like on a lab diagnosis when serious infection
pink colony- ferments lactose
urine examination shows pus cells
What is travelers diarrhea due to?
drinking water that has been contaminated by sewage
What is neonatal sepsis due to?
presence of E.coli in vagina of pregnant women
Treatment for GIT infection
no treatment, self-limiting, supplemental fluid may be necessary
Treatment for UTI infection
Oral trimethoprim and sulphamethoxazole/cephalosprin and amino glycoside
presence of what organism in drinking water is indicative of sewage contamination?
What can be done to remove coliform organisms from water?
chlorination of water
gram - rod that causes typhoid fever
Salmonella-- only through ingestion
How does salmonella move?
has a ton of flagellum
S.Typhi and S.Paratyphi are fever producing
non typhoidal species
diarrhea producing- Salm. Typhi murium is most common cause of diarrhea in US
Mode of transmission of salmonella
ingestion of food and water contaminated with human or animal waste
Is there an animal source of transmission for S. Typhi?
No- only human
So typhoid fever is mainly due to...?
water contamination with fecal materials- not animal source