M11 Gram Negative Bacteria 2 Flashcards Preview

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Flashcards in M11 Gram Negative Bacteria 2 Deck (56):
1

what are some gram negative anaerobic bacilli that are motile

selenomonaos
centipeda
helicobacter

2

what are some gram negative anaerobic bacilli that are non motile

bactericides
prophorymonans
prevotella
tannerlla
fusobac
leptotrichia

3

what is tannerella forsythia

saccharolytic
non pigmented bacteria

4

what does tannerlla forsythia do to blood agar

pits the surface

5

what is tannerlla forsythia associated with

periodontitis
but not when in isolation

6

what are some virulence factors of tannerlla forsythia

fibronectin
apoptosis inducing factor
protease
hemagglutinin
mirolysin

7

what is fibronectin do

BspA
adhesion
invasion
induces release bone reads pro inflam cytokines
induces chemokine

8

what do chemokine do

recruit neutrophils
inflammation
tissue destruction

9

how is the pathogenicity of tannerella forsythia limited

polymicrobial
wound chamber does not cause disease
gnotobiotic rats dont colonise efficiently

10

what are the interactions of tannerlaa forsythia

P gingival - enhances attachment to epi cells
forms mixed films with fusobac

11

what is fusobacterium

gram -ve spindle shaped FUSIFORM bac
pathogenic

12

what are some sub species of fusobacterium nucleate

nucleatum
polymorphism
vincentii

13

what can fusobac bind

gram -ve and +ve

14

what is fusobac mostly involved in

saccharolytic
binding organism

15

where does fusobac colonise

gingival sulus

16

what is the fusobacterium linked to

endotoxin linked to periodontitis

17

what virulence factor of fusobac is involved in extra oral infections

FadA
binds to epi cells
enter fibroblasts

18

what is fusobac nucleatum involved in

acute ulcerative gingivitis AUG

19

what is usually assc with fusobac nucleatum

treponema vincentii
spirochaete
= fusospirochateal infection

20

whatcondiion is assc with fusobac nucleatum

vincents angina
cancrum oris ( AUG tissue destroy and immunosuppression)

21

when is AUG most common

young adults
smokers
ulcers on marginal margins

22

what can happen from AUG

gingival sore and bleed
foul breath
no fever
no swollen lymph nodes

23

what does fusobac do in terms of AUG

induce P kinases assc with cell prolif and migration
stim coagulase 3 expression
immune suppression by apoptosis

24

what does F nucelatum mediate

co invasion of s cristasus

25

what is F nucelatum mechanism proposed for

colon cancer

26

what is leptotrichia

gram -ve anaerobic bacilli
saccharolytic
in pairs
lactic acid

27

what is the main species of leptorichia

buccalis

28

what are the features of L buccalis

dental plaque
isolated from plaque over caries
galacto syl binding lectins
extra oral infections

29

what are gram -ve facultative anaerobes

prefer oxygen
capnophilic (5-10% co2)

30

what are some facultative anaerobes

haemophilia
aggregatibacter
eikenella
capnocytophaga

31

what is haempphilus and where is usually found

gram -ve
small bacilli
mouth and plaque

32

when are haemophilus present

first few days after birth

33

what is the most common haemophilia and where is it found

H segnis
supra gingival plaque

34

is haemohilus pathogenic

not particularly

35

what are he main aggregatibacter

atinomycetecomitans

36

what is aggregatibacter

oral sp in gingival sulcus
gm -ve
capnophilic
cocci-bacillus
periodontopathogen

37

what are some virulence factors for aggreatibacter

leukotriene
collegenase
IgG proteases
surface proteins

38

what does leukotoxin do

take out leucocytes

39

what is juvenile periodontitis

puberty
girls
localised - First molars and incisors
generalised is aggressive

40

what is high in microflora in local JP and what is there

actinomycetmcomitans
LPS - pro inflam endotoxin and promote bone loss

41

what does A actinomycetecomitans do

rapid destruction periodontitis
JP
papillon leferve syndrome

42

what is pavilion lefevre syndrome

skin condone
teeth loss
thick cracked skin

43

what is prescribed for JP

tetracycline and beta lactamase

44

what is eikenella

gm -ve asaccharolytic small bacillus pits agar

45

what is a sp of eikenella and where found

E corrodens
sub gingival plaque

46

what can eikenella do

periodontitis
alveolar bone loss
inc gingiviis
clench fist injuries

47

what is capnocytophaga

gm -ve fusiform Co2 dept
motile

48

what are some subspecies of capnocytophaga

ochraceae
sputigena
gingivalis

49

what does capnocytophaga

periodontitis
JP

50

what is an example of curved gm -ve bacilli and where found

campylobacter rectus
plaque and per pocket

51

how does periodontitis come about

progression from health to gingivitis to periodnotitits

52

what is seen in health

facultative
- (+) rods and cocci
anaerobic
-(-) rods
-(+) rods, cocci

53

what is seen in gingivitis

facultative
- (+) cocci
- (+) rods
- (-) rods
anaerobic
- (-) rods
- (-) cocci
- (+) rods

54

what is seen in periodontitis

facultative
- (+) rods
- (+) cocci
anaerobic
- (-) Rods
- (+) rods

55

what is the red complex

tannerella forsythia
porphyromonas
gingivalis
treponema denticola

56

what is the orange complex

prevotella intermedia
prevotella nigrescens
fusobacterium nucleatum