M11 Gram Negative Bacteria 2

Question 1

what are some gram negative anaerobic bacilli that are motile

Answer 1

selenomonaos
centipeda
helicobacter

Question 2

what are some gram negative anaerobic bacilli that are non motile

Answer 2

bactericides 
prophorymonans
prevotella
tannerlla
fusobac
leptotrichia

Question 3

what is tannerella forsythia

Answer 3

saccharolytic

non pigmented bacteria

Question 4

what does tannerlla forsythia do to blood agar

Answer 4

pits the surface

Question 5

what is tannerlla forsythia associated with

Answer 5

periodontitis

but not when in isolation

Question 6

what are some virulence factors of tannerlla forsythia

Answer 6

fibronectin 
apoptosis inducing factor 
protease
hemagglutinin 
mirolysin

Question 7

what is fibronectin do

Answer 7

BspA
adhesion
invasion 
induces release bone reads pro inflam cytokines 
induces chemokine

Question 8

what do chemokine do

Answer 8

recruit neutrophils
inflammation
tissue destruction

Question 9

how is the pathogenicity of tannerella forsythia limited

Answer 9

polymicrobial
wound chamber does not cause disease
gnotobiotic rats dont colonise efficiently

Question 10

what are the interactions of tannerlaa forsythia

Answer 10

P gingival - enhances attachment to epi cells

forms mixed films with fusobac

Question 11

what is fusobacterium

Answer 11

gram -ve spindle shaped FUSIFORM bac

pathogenic

Question 12

what are some sub species of fusobacterium nucleate

Answer 12

nucleatum
polymorphism
vincentii

Question 13

what can fusobac bind

Answer 13

gram -ve and +ve

Question 14

what is fusobac mostly involved in

Answer 14

saccharolytic

binding organism

Question 15

where does fusobac colonise

Answer 15

gingival sulus

Question 16

what is the fusobacterium linked to

Answer 16

endotoxin linked to periodontitis

Question 17

what virulence factor of fusobac is involved in extra oral infections

Answer 17

FadA
binds to epi cells
enter fibroblasts

Question 18

what is fusobac nucleatum involved in

Answer 18

acute ulcerative gingivitis AUG

Question 19

what is usually assc with fusobac nucleatum

Answer 19

treponema vincentii
spirochaete
= fusospirochateal infection

Question 20

whatcondiion is assc with fusobac nucleatum

Answer 20

vincents angina
cancrum oris ( AUG tissue destroy and immunosuppression)

Question 21

when is AUG most common

Answer 21

young adults
smokers
ulcers on marginal margins

Question 22

what can happen from AUG

Answer 22

gingival sore and bleed
foul breath
no fever
no swollen lymph nodes

Question 23

what does fusobac do in terms of AUG

Answer 23

induce P kinases assc with cell prolif and migration
stim coagulase 3 expression
immune suppression by apoptosis

Question 24

what does F nucelatum mediate

Answer 24

co invasion of s cristasus

Question 25

what is F nucelatum mechanism proposed for

Answer 25

colon cancer

Question 26

what is leptotrichia

Answer 26

gram -ve anaerobic bacilli saccharolytic in pairs lactic acid

Question 27

what is the main species of leptorichia

Answer 27

buccalis

Question 28

what are the features of L buccalis

Answer 28

dental plaque isolated from plaque over caries galacto syl binding lectins extra oral infections

Question 29

what are gram -ve facultative anaerobes

Answer 29

prefer oxygen | capnophilic (5-10% co2)

Question 30

what are some facultative anaerobes

Answer 30

haemophilia aggregatibacter eikenella capnocytophaga

Question 31

what is haempphilus and where is usually found

Answer 31

gram -ve small bacilli mouth and plaque

Question 32

when are haemophilus present

Answer 32

first few days after birth

Question 33

what is the most common haemophilia and where is it found

Answer 33

H segnis | supra gingival plaque

Question 34

is haemohilus pathogenic

Answer 34

not particularly

Question 35

what are he main aggregatibacter

Answer 35

atinomycetecomitans

Question 36

what is aggregatibacter

Answer 36

``` oral sp in gingival sulcus gm -ve capnophilic cocci-bacillus periodontopathogen ```

Question 37

what are some virulence factors for aggreatibacter

Answer 37

leukotriene collegenase IgG proteases surface proteins

Question 38

what does leukotoxin do

Answer 38

take out leucocytes

Question 39

what is juvenile periodontitis

Answer 39

puberty girls localised - First molars and incisors generalised is aggressive

Question 40

what is high in microflora in local JP and what is there

Answer 40

actinomycetmcomitans | LPS - pro inflam endotoxin and promote bone loss

Question 41

what does A actinomycetecomitans do

Answer 41

rapid destruction periodontitis JP papillon leferve syndrome

Question 42

what is pavilion lefevre syndrome

Answer 42

skin condone teeth loss thick cracked skin

Question 43

what is prescribed for JP

Answer 43

tetracycline and beta lactamase

Question 44

what is eikenella

Answer 44

gm -ve asaccharolytic small bacillus pits agar

Question 45

what is a sp of eikenella and where found

Answer 45

E corrodens | sub gingival plaque

Question 46

what can eikenella do

Answer 46

periodontitis alveolar bone loss inc gingiviis clench fist injuries

Question 47

what is capnocytophaga

Answer 47

gm -ve fusiform Co2 dept | motile

Question 48

what are some subspecies of capnocytophaga

Answer 48

ochraceae sputigena gingivalis

Question 49

what does capnocytophaga

Answer 49

periodontitis | JP

Question 50

what is an example of curved gm -ve bacilli and where found

Answer 50

campylobacter rectus | plaque and per pocket

Question 51

how does periodontitis come about

Answer 51

progression from health to gingivitis to periodnotitits

Question 52

what is seen in health

Answer 52

``` facultative - (+) rods and cocci anaerobic -(-) rods -(+) rods, cocci ```

Question 53

what is seen in gingivitis

Answer 53

``` facultative - (+) cocci - (+) rods - (-) rods anaerobic - (-) rods - (-) cocci - (+) rods ```

Question 54

what is seen in periodontitis

Answer 54

``` facultative - (+) rods - (+) cocci anaerobic - (-) Rods - (+) rods ```

Question 55

what is the red complex

Answer 55

tannerella forsythia porphyromonas gingivalis treponema denticola

Question 56

what is the orange complex

Answer 56

prevotella intermedia prevotella nigrescens fusobacterium nucleatum