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Flashcards in Medications/DMARDs Deck (25)
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1

name the 6 drug families that are given for ischaemic heart disease

1. ACE inhibitors
2. Statins
3. B-blockers
4. Calcium channel blockers
5. nitrates
6. others ie nicorandil

2

5 drug families given for hypertension

1. ACE inhibitors
2. angiotensin 2 receptor antagonists
3. B-blockers
4. Calcium channel blockers
5. Diuretics

3

what are the 4 drugs given for heart failure?

- ACE inhibitors/angiotensin 2 receptor antagonists
- B-blockers
- diuretics
- digoxin

4

what medication id given in valvular disease?

anticoagulants

5

what medications are given for arrythmias?

- Anti-coagulants
- B-blockers
- Calcium agonists
- Digoxin
- Amiodarone

6

what 3 types of drugs can give MRONJ?

- bisphosphonates
- denosumab
- anti-angiogenics

7

name 2 anti-angiogenics

1. sunitinib
2. bevacizumab

8

what are anti-angiogenics given for?

as cancer tx (esp if bone metastases)

9

what are some of the oral effects of anti-angiogenics (3)

-taste d
-oral mucositis
-vomitting

10

what is denosumab given for?

- postmenopasal women with osteoporosis
- men with prostate cancer at risk of fractures
- bone metastases

11

what are the 5 medication groups that are given to patients with asthma?

- short acting B-2 agonist
- long acting B-2 agonist
- steroid
- anti-leukotrienes
- systemic steroids

12

name a systemic steroid?

- prednisolone

13

what are all the main uses for prednisolone?

- asthma
- COPD

- rheumatoid arthritis
- SLE

- giant cell (temporal) arteritis
- prophylaxis of episodic cluster headaches

- ulcerative colitis
- chrons disease

14

what (in addition to all the asthma drugs) are taken for COPD?

- short acting muscarinic antagonists (ipatropium)
- long acting muscatinic antagonists (tiotropium)
- mucolytic (carbonaisteine)
- antibiotics (azithromycin)

15

name 2 corticosteroid drugs

1. hydrocortisone
2. triamcinolone

16

what are the 2 possible side effects of corticosteroids that require monitoring>

- BP changes
- hyperglycaemia

17

what are some oral effects of corticosteriods?

- candidosis
- MRONJ

18

what are 2 diseases that can occur due to taking corticosteroids?

- cushing syndrome
- osteoperosis

19

name some DMARDs

- methotrexate
- ciclosporin
- hydrochloroquine
- azathiopine
- sulfasalazine
- gold
- lefunomide
- myocophenolate mofietil

20

2 ways methotrexate can be delivered are?

orally
subcutaneous injection

21

2 ways that azathiopine can be administered are?

orally
intravenously

22

what is the dose of methtrexate given?

7.5 - 15mg (max is 25mg)

taken 1x a week

23

what is the dose of azathipine given?

1-3mg/kg

24

what are the dental aspects of DMARDs?

- oral ulceration
- neutropenia ( increased susceptibility to infection)

25

what patients will receive biologics - monoclonal antibody therapy?

those who have failed to respond to at lease 2 DMARDs