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Flashcards in Neuro Deck (77)
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61

Charcot-Marie-tooth Disease (Hereditary Motor and sensory Neuropathy)

progressive hereditary nerve disorders d/t defective myelin sheath protein production

62

Most common 1mary brain tumor?

Glioblastoma Multiforme (GBM): p53 mutation, crosses corpus callosum "butterfly" and "pseudopalisading" tumor cells, contrast enhancing lesion within cerebral hemispheres on MRI

63

Meningioma keywords

whorled
psammoma bodies
near brain surface

64

Oligodendroglioma keywords

frontal lobe
chicken-wire capillary
"fried egg"

65

Most common childhood brain tumor?

Pilocytic astrocytoma: @ post. fossa, GFAP+, Rosenthal corkscrew fibers, benign

66

Medulloblastoma keywords

hydrocephalus
Homer-Wright rosettes
small blue cells

Tx: Radiation

67

Uncal (medial temporal lobe) Herniation keywords

fixed dilated pupil ipsilaterally
contralat. homonymous hemianopsia
ipsilateral hemiparesis

68

S&S of Posterior Cerebral A. occlusion (LEFT)

RIGHT hemianopsia
RIGHT sensory deficits
Alexia without agraphia
Difficulty forming new memories
Anomic aphasia
Gerstman's Syndrome (acalculia, agraphia, finger agnosia, right-left disorientation)

69

Atypical meningitis can be caused by what immunosuppressive medication?

MTX: causes myelosuppression leading to neutropenia

70

Empiric Tx. for Meningitis

"Be a life SAVeR"

Steroids
Acyclovir & Ampicillin
Vancomycin
Rocephin (Ceftriaxone)

71

Ataxia-Telangiectasia

S&S

Labs

Ataxia (wide based gait and instability)
Telangiectasia (dilated tortuous conjunctiva) in skin, eyes
Recurrent sinopulmonary infections

Almost ZERO IgA with Elevated IgM, Normal IgG

72

Dx of Benign Paroxysmal Positional Vertigo?

Tx?

Dx: Dix-Hallpike

Tx: Epley maneuver

73

S&S of Internal Carotid A. dissection

v. Vertebral a. dissection

ipsilateral cranial nerve deficits (e.g. ptosis, miosis, weak shoulder raise)

while a Vertebral a. dissection will show Horner's Syn.

74

Tx. Trigeminal Neuralgia

Carbamazepine

75

Meniere's Disease

Ppx?

HCTZ + Triamterene reduce endolymph in the semicircular canals

76

Common migraine

S&S

Ppx

Tx

Frequent constant headache that doesn't come with flashing lights, motor weakness, aura, or dizziness

PPx: Propranolol, Verapamil

Tx: Sumatriptan

77

Most common cause meningitis in people >35 y.o.

Strep pneumo ( G+ diplococci)