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Flashcards in Neurology druuggz Deck (209)
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1

list the strategies for treating glaucoma

alpha agonists - decrease synthesis (hurts my brain bc on dilator muscles and that's it)
beta blockers - decrease synthesis
diuretics - to decreased IOP
cholinomimetics - to increase outflow fo aqueous humor
prostaglandins - to increase outflow of aqueous humor

2

what durg is not to be used in closed angle galucoma

epinephrine bc causes mydriasis - bad news bears

3

how does epinephrine decreased aqueous humor

alpha 1 agonist - decreases aqeous humor production by vasoconstriction

4

how does brimonidine work for glaucoma

alpha two agonist - decreases aqueous humor production

5

what are the side effects of epinephrine and brominidine for glaucoma treatment

blurry vision
ocular hyperemia
doreign body sensation
ovcular allergic reactions
ocular pruritis

6

which drug?
blurry vision
ocular hyperemia
foreing body sensation
ocular allergic reactions
ocular pruritus

epinephrine - alpha 1 agonist
brimodine - alpha 2 agonist

7

what beat blockers are used to treat glaucoma

timolol
betaxolol
carteolol

8

what are betaxolol and carteolol used for

glaucoma with timolol

9

how to timolol betaxolol and carteolol treat glaucoma

beta blockers - decreasd aqueous humor production

10

what are the s/e of betaxolol and carteolol and timolol when used for glaucoma treatment?

no pupillary or vision chances

11

what diuretic is used for glaucoma treatment

acetazoloamide

12

how does acetazolamide help in glaucoma

decreases aqueoue humor synthesis via inhibition of carbonic anhydrase

13

a/se relevated to acetazolamide treatment for glaucoma

no pupillary or vision changes

14

what are the direct cholinomimetics used to treat gluacoma

pilocarpine and carbachol

15

how do pilocarpine and carbachol help with galucoma

increased outflow by constricting the ciliary muscle and opening the trabecular meshwork

16

what are the indirect cholinomimetics used to treat gluacoma

physostigmine and echothiophate

17

how do physostigmine and echothiophate work to help with glaucoma

increased outflow of aqueous humor via contraction of ciliary muscle
open trabecular meshwork

18

what are a/se of cholinomimetics when used for gluacoma

miosis and cyclospam - contraction of ciliary msucle

19

what drugs to choose if done want any pupillary of vision a/se for glaucoma

beta blockers: timolol, betaxolol, carteolol
diuretics: acetazolamide

20

what durgs to choose for glaucoma if don't mind pupillary or vision a/se

alpha agonists: epinephrine and brimonidine
cholinomimetis: carbachol, pilocarpine, physostigmine, echothiophate

21

what drug to use in glaucoma emergencies and why please

pilocarpine - bc especially good at opening meschwork into the canal of schlemm

22

what pg is used for glaucoma treatment

latanoprost PGF2a analog

23

what does latanoprost/PGF2a do for help in glaucoma

increases outflow of aqueous humor

24

what are a/se of latanoprost

browns up the iris

25

list the opioid analgesics please

morphine
fentanyl
codeine
loperamide
methadone
meperidine
destromethrophan
diphenoxylate
pentazocine

26

what is the MOA of opioid analgesics

agonists at opiod recetors, m, d, k to modulate synaptic transmission - increase K and decreased Ca - decreases synaptic transmission - inhibits the release of a) Ach b( NE c) 5Ht, d) flutamate and e) substance P

27

what neurotransmitters do opiod analgesics decrease release of

NE, Ach, glutamate, substance P, 5Ht

28

again what neurotransmitters do opioid analgesics decrease

Ach, NE, glutamate, 5 Ht, substance P

29

what is destromethrophan used for

opioid
cough suppression

30

what is loperamide and diphenoxylate used for

diarrhoea