Flashcards in Drug toxicity and a/se Deck (45):
1
coronary vasospasm
cocain, suatriptan, ergot alkaloids
2
cutaneous flushing
vancomycin, adenosime, niacin, CCB
3
dilated cardiomyopathy
doxorubicin, daunorubicin
4
torsades de poitnes
class III, class Ia, macrolide antibiotics, antipsychotics, TCAs
5
adrenocortical insufficiency
secondary to glucocorticoid withdrawl
6
hot flashes
tamoxifen, clomiphene
7
hyperglycemia
tacrolimus, protease inhibitors, niacin MCTZ, coricosteroids
8
hypthyroidism
lithium, amiodarne, sulfonamides
9
acute cholestatic hepatitis jaundice
erythromycin
10
diarrhoea
metforim, erythromycin, colchicine, orlistate, acarbose
11
focal to massive hepatic necrosis
halothane, amanita phalloides, acetaminophen, calporic acid
12
hepatitis
rifampin, isoniazind, pyrazinamide, statins, fibrates
13
pancreatitis
alcohol, azathioprine, didanosine, corticosteroids, valproic acid, furosemide, HCTZ
14
agranulocytosis
ganciclovir, clozapine, colchicine, carbamazepine, methimazole, propylthiouracil
15
aplastic anaemia
benzene, NSAIDs, chloramphenicol, carbamazepine, methimazole, propylthiouracil
16
direct coombs positive anaemia
methyldopa, penicillin
17
gray baby syndrome
chloramphenicol
18
hemolysis in G6PD deficiency
isoniazid, sulfonamides, dapson, primaquine, aspirin, ibuprofen, bitrfurantoin
19
megaloblastic anaemia
phenytoin, methotrexate, sulfa drugs
20
thrombocytopenia
heparin
21
thrombotic complicatiosn
OCP, HRT
22
fat redistribution
protease inhibitiors, corticosteroids
23
gingival hyperplasi
phenytoin, CCB, cyclosporine
24
hypuricemia
thiazides, furosemide, pyrazinamide, niacin, cyclosporine
25
myopathy
colchicine, fibrates, glucocorticoids ,hydroxychloroquine, IFNa, niacin, penicillamine, statins
26
osteoporosis
corticosteroids, heparin
27
photosensitivity
seulfonamides, amiodarone, tetracyclines, 5-FU
28
steven-johnson syndrome
antiepileptic, allopurinol, sulfa, penicillin
29
SLE-like syndrome
sulfa drugs, hydralazine, isoniazis, procainamide, phenytoin, etanercept
30
teeth discolouration
tetracyclines
31
tendonitis, tendon reupture, cartilage damage
fluoroquinolones
32
cinchonism
quinidine, quinine
33
Parkinson-like syndrome
antipsychotics, reserpine, metoclopramide
34
seizures
isoniazid/vit B6 def, bupropion, imipenum/cilastatin, enflurane
35
tardive dyskinesia
antipsychotics, metoclopramide
36
diabetes insipidus
lithium, demeclocycline
37
fanconi syndrome
expired tetracycline
38
hemorrhagic cystistis
cyclophosphamide, ifosfamide
39
interstitial nephritis
methicillin, NSAIs, furosemide
40
SIADH
carbamazepine, cyclophosphamide, SSRIs
41
dry cough
ACE inhibitors
42
pulmonary fiboriss
bleomycin, busulfan, amiodarone, methotrexate
43
antimuscarinic
atropine, TCA, antipsychoitcs, H1 blockers
44
disulfiram like reactin
my cereal goes snap pop: metronisazole, cephalosporins, grisefulvin, procarbazine, fist gen sulfonylureas
45