Flashcards in Psychiatry Deck (86):
1
DOC @ ADHD
stimulants
2
DOC @ OH withdrawal
long acting benzos
chlordiazeoxide, lorazepma, diazepam
3
DOC @ bipolar
litiuim, valproid acid, atypical antypsychotics ( olanzapine, clozapine, queitapine, risperidone, aripiprazole, ziprasidone)
4
DOC @ bulimia
SSRI ( fluoxetine, paroxetine, sertraline, citalopram)
5
DOC @ depression
SSRI (fluoxetine, paroxetine, sertraline, citalopram)
6
DOC @ GAD
SSRI (fluoxetine, paroxetine, sertraline, citalopram)
SNRI (venlafaxine, duloxetine)
busprion
7
DOC @ schizophrenia
atypical antipsychotics (haloperidol, trifluoperazine, flupenazine, thioridazine, chlorpromazine)
-AZINES
8
DOC @ social phobias
SSRIs (fluoxetine, paroxetine, sertraline, citalopram)
beta blockers
9
DOC @ OCD
SSRIs (fluoxetine, paroxetine, sertraline, citalopram)
clomipramine (TCA)
10
DOC @ panic disorder
SSRI (fluoxetine, paroxetine, sertraline, citalopram)
venlafaxine (SNRI)
benzodiazepines
11
DOC @ PTSD
SSRI (fluoxetine, paroxetine, sertraline, citalopram)
venlafaxine (SNRI)
12
DOC @ Tourette syndrome
antipsychtics (fluphenazien, pimozide)
tertrabenazine
13
uses of methylphenidate, destroamphetamine methamphetamie
ADHD
narcolepsy
appetite stimulant
14
increased NE and DA especially used for ADHD
CNS stimulatns
15
increses NE and DA
CNS stimulants
buproprion
16
list the typicl antipsychotics
haloperisol
trifluoperazine
fluphenazine
thioridazine
chlorpromazine
17
moa of typical antipsychotics
block D2 -- increase cAMP
18
uses of typical antipsychotics
positive symptoms of schizophrena
psychosis
acute mania
Tourette syndrome
19
high potency typical antipsychotics please
haloperidol
trifluoperazine
fluphenazine
TRY to FLY High
20
low potency typical antipsychotics please
chlorpromazine
thioridazine
21
a/se of typical antipsychotics in general
EPS
endocrine - hyperprolacti
anticholi - dry mouth, constipation
antiadrena1 - hypotension
antihista - sedation
22
what can cause QT prolongation
typical antipsychotics
atypical antipsychotics
TCAs
23
what s/e with haloperidol
EPS
Neurleptic malignant syndrome
tardive dyskinesia
24
what s/e with trifluoperazine and fluphenazine
eps - huntingot, delirium,
25
what s/e with chlorpormazine
anti choli
anti alpha 1
anti histamine
corneal deposits
26
what s/e with thioridazine
anti choli
anti alpha 1
anti histamine
retinal deposits
27
rigidity
Myoglobinuria
autonomic instability
hyperpyreia
neuroleptic malignany syndrome
haloperidol
28
how do you treat rigidity/Myoglobinuria/autonomic instability/hyperpyrexia with haloperid use
dantrolene
D2 agonists - bromocriptin
29
descrien the evolution of EPS sides efects
4 hours acute dystonia (muscle spasm, stiffness, oculogyric crisis)
4 day akathisia/restlessness
4 week bradykinesia/parkinsonism
4 month tardive dyskinesia
30
symptoms of neuroleptic malignancy syndrome
ridigity, Myoglobinuria, autonomic instability, hyperpyrexia
treat with dantrolene and D2 agonist ie bromocription
FEVER
fever
encephalopathy
vitals unstable
enzymes increase d(muscle)
rigidity of muscles
31
how do you treat the extrapyramidal system side effects of high potentncy typical antipsychotis
haloperidol, trifluoperazine, fluphenazie
BENZTROPINE and DIPHENHYDRAMIE
32
used of benztropine and diphenhydramine
eps symptoms of high potency typical antipsychotics
33
list the atypical antipsychotics please
olanzapine, clozapine, quetiapine
resperidone
aripiprazole, ziprasidone
34
MOA of atypical antipsychotics please
not completely udnerstonnd
varied at 5HT2, dopamine, H1 and Ne receptors
35
use of atypical antipsychotics please
positive and negative schizophrenia
bipolar
OCD
anxiety
tourettes
depression
mania
36
how do s/e between typical and atypical antipsychotics vary
less eps and anticholis in atypical
37
s/ae of clozapine please
AGRANULOCYTOSIS, weight gain, seizure
38
a/se of olanzapine please
weight gain
39
a/se of resiperidone
increased prolactin
lactatin, gynecomastia
irregular menstratuion
fertility issues
40
a/se of all atypical antipscyhotics
QT prolongation
41
what is moa of lithium
not really known
inhibit of phosphoinositol cascaise
42
use of lithium
SIADH (wherease SSRi cause)
mood stabilized for bipolar
blocks relapse and acute main
43
a/se of lithium
tremor
hypothyroidism
ebstein anomaly in pregos
nephrogenic diabetes insipidius
kidney
44
what do you use in lithium toxocity
thiazides
45
moa of busprion
stimulats 5HT1a
46
use of busprion
GAD (alsoSSRi and SNRI)
47
benefits of busprion
no addiction, tolerance, sedation
no interaction with OH (barbiturates and benzos do)
48
list the SSRIs please
fluoxetine
paroxetine
sertraline
citalopram
49
MOA of SSRIs please
5ht reuptake inhibitors
50
used of SSRI
depression
GAD
panic disorder
OCD
bulimia
social phobias
PTSD
51
a/se of SSRI
serotonin syndrome (Ssri, snri, tca, maoi, meeperidine, )
gi distress
sexual dysfunction - anorgasmia, decreased libido
52
hyperthermia
confusion
myoclonus
cardiovascular instability
flushing
diarrhoea
seizures
serotonin syndrome
53
how to treat serotonin syndrome
cyproheptadine a 5HT2 antag
54
sxs fo serotonin syndrome
hyperthermia
confusion
myoclonus
cardiovascular instability
flushing
diarrhoea
seizures
55
lsit the snris please
venlafaxine, duloxetine
56
diabetic peripheral neupahty
duloxetine
57
moa of snris
inhibit Ne and 5Ht reuptake
58
ase of SNRIs
increased bp most common
stimulant effects
sedation
nausea
59
useds of venlafaxine
depression, GAD, panic disorder, PTSD
60
list the tcas please
amitriptyline, nortriptyline
imipramine, desipramiine, clomipramine
doxepin, amoxapine
61
moa of tca
block reuptae of Ne and 5ht
62
uses of tca
major depression
ocd - clomipramine
peripheral neuropathy
chronic pain
migraine prophylaxis
63
migraine prophylaxis
tcas
64
chronic pain
tcas
65
a/se of tcas
anti alpha 1
anti chloi
prolongation of qt itnerval
66
tca to use in elderly and why
nortriptyline bc less anticholis that would cause confusion and halluciations
67
how to prevent arrhythmia with tca use
naHCo3
68
serious a/se of tcas
coma
convulsions
cardiotoxicity
resp depression
69
NaHCO3
prevent arrhythmias in TCAs
70
list the MAOis please
MAO takes pride in changhai
tranylcypromine
phenelzine
isocarboxazid
selegiline
71
how is selegiline diff
selevite MAO B inhibitor
72
what is the moa of maois?
nonselectie MAO inhibition increases amine NT ie Ne, 5Ht, and Da
73
uses of MAOis
atypical depression
anxiety
74
a/se of maois
hypertensive crisis with tyramine
CNS stimulation
75
contraindicated at maois
cheese and wine - hypertensive crisis
serotonin syndrome - ssri, tca, st johsn wart, meperidine, dextromethorphan
76
use of buproprion
smoking cessation
77
moa of buproprion
increase ne and da with unknown moa
78
a/se of buproprion
stimulatnt - tach and insomnia
headache
seizures in anorexic/bulimic patients
79
what is buproprion godo for
no sexy time effects
80
moa of mirtazapine
inhibits alpha 2 -- increase Ne and 5HT release
5Ht2 and 5HT3 inhibitiors
81
uses of miertazapine
depression - want to sleep bc causes sedation
weight gain in elderly or anorexix (also causes increased appetite)
82
a/se fo miertazapine
sedation
weight gain
increased appetite
dry mouth
83
what is trazodone known for
priapism
84
moa of trazodone
blocsk 5HT2 and alpha 1
85
what is trazodone used for
insomina
86