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Flashcards in Psychiatry Deck (86):
1

DOC @ ADHD

stimulants

2

DOC @ OH withdrawal

long acting benzos
chlordiazeoxide, lorazepma, diazepam

3

DOC @ bipolar

litiuim, valproid acid, atypical antypsychotics ( olanzapine, clozapine, queitapine, risperidone, aripiprazole, ziprasidone)

4

DOC @ bulimia

SSRI ( fluoxetine, paroxetine, sertraline, citalopram)

5

DOC @ depression

SSRI (fluoxetine, paroxetine, sertraline, citalopram)

6

DOC @ GAD

SSRI (fluoxetine, paroxetine, sertraline, citalopram)
SNRI (venlafaxine, duloxetine)
busprion

7

DOC @ schizophrenia

atypical antipsychotics (haloperidol, trifluoperazine, flupenazine, thioridazine, chlorpromazine)
-AZINES

8

DOC @ social phobias

SSRIs (fluoxetine, paroxetine, sertraline, citalopram)
beta blockers

9

DOC @ OCD

SSRIs (fluoxetine, paroxetine, sertraline, citalopram)
clomipramine (TCA)

10

DOC @ panic disorder

SSRI (fluoxetine, paroxetine, sertraline, citalopram)
venlafaxine (SNRI)
benzodiazepines

11

DOC @ PTSD

SSRI (fluoxetine, paroxetine, sertraline, citalopram)
venlafaxine (SNRI)

12

DOC @ Tourette syndrome

antipsychtics (fluphenazien, pimozide)
tertrabenazine

13

uses of methylphenidate, destroamphetamine methamphetamie

ADHD
narcolepsy
appetite stimulant

14

increased NE and DA especially used for ADHD

CNS stimulatns

15

increses NE and DA

CNS stimulants
buproprion

16

list the typicl antipsychotics

haloperisol
trifluoperazine
fluphenazine
thioridazine
chlorpromazine

17

moa of typical antipsychotics

block D2 -- increase cAMP

18

uses of typical antipsychotics

positive symptoms of schizophrena
psychosis
acute mania
Tourette syndrome

19

high potency typical antipsychotics please

haloperidol
trifluoperazine
fluphenazine
TRY to FLY High

20

low potency typical antipsychotics please

chlorpromazine
thioridazine

21

a/se of typical antipsychotics in general

EPS
endocrine - hyperprolacti
anticholi - dry mouth, constipation
antiadrena1 - hypotension
antihista - sedation

22

what can cause QT prolongation

typical antipsychotics
atypical antipsychotics
TCAs

23

what s/e with haloperidol

EPS
Neurleptic malignant syndrome
tardive dyskinesia

24

what s/e with trifluoperazine and fluphenazine

eps - huntingot, delirium,

25

what s/e with chlorpormazine

anti choli
anti alpha 1
anti histamine
corneal deposits

26

what s/e with thioridazine

anti choli
anti alpha 1
anti histamine
retinal deposits

27

rigidity
Myoglobinuria
autonomic instability
hyperpyreia

neuroleptic malignany syndrome
haloperidol

28

how do you treat rigidity/Myoglobinuria/autonomic instability/hyperpyrexia with haloperid use

dantrolene
D2 agonists - bromocriptin

29

descrien the evolution of EPS sides efects

4 hours acute dystonia (muscle spasm, stiffness, oculogyric crisis)
4 day akathisia/restlessness
4 week bradykinesia/parkinsonism
4 month tardive dyskinesia

30

symptoms of neuroleptic malignancy syndrome

ridigity, Myoglobinuria, autonomic instability, hyperpyrexia
treat with dantrolene and D2 agonist ie bromocription
FEVER
fever
encephalopathy
vitals unstable
enzymes increase d(muscle)
rigidity of muscles

31

how do you treat the extrapyramidal system side effects of high potentncy typical antipsychotis

haloperidol, trifluoperazine, fluphenazie
BENZTROPINE and DIPHENHYDRAMIE

32

used of benztropine and diphenhydramine

eps symptoms of high potency typical antipsychotics

33

list the atypical antipsychotics please

olanzapine, clozapine, quetiapine
resperidone
aripiprazole, ziprasidone

34

MOA of atypical antipsychotics please

not completely udnerstonnd
varied at 5HT2, dopamine, H1 and Ne receptors

35

use of atypical antipsychotics please

positive and negative schizophrenia
bipolar
OCD
anxiety
tourettes
depression
mania

36

how do s/e between typical and atypical antipsychotics vary

less eps and anticholis in atypical

37

s/ae of clozapine please

AGRANULOCYTOSIS, weight gain, seizure

38

a/se of olanzapine please

weight gain

39

a/se of resiperidone

increased prolactin
lactatin, gynecomastia
irregular menstratuion
fertility issues

40

a/se of all atypical antipscyhotics

QT prolongation

41

what is moa of lithium

not really known
inhibit of phosphoinositol cascaise

42

use of lithium

SIADH (wherease SSRi cause)
mood stabilized for bipolar
blocks relapse and acute main

43

a/se of lithium

tremor
hypothyroidism
ebstein anomaly in pregos
nephrogenic diabetes insipidius
kidney

44

what do you use in lithium toxocity

thiazides

45

moa of busprion

stimulats 5HT1a

46

use of busprion

GAD (alsoSSRi and SNRI)

47

benefits of busprion

no addiction, tolerance, sedation
no interaction with OH (barbiturates and benzos do)

48

list the SSRIs please

fluoxetine
paroxetine
sertraline
citalopram

49

MOA of SSRIs please

5ht reuptake inhibitors

50

used of SSRI

depression
GAD
panic disorder
OCD
bulimia
social phobias
PTSD

51

a/se of SSRI

serotonin syndrome (Ssri, snri, tca, maoi, meeperidine, )
gi distress
sexual dysfunction - anorgasmia, decreased libido

52

hyperthermia
confusion
myoclonus
cardiovascular instability
flushing
diarrhoea
seizures

serotonin syndrome

53

how to treat serotonin syndrome

cyproheptadine a 5HT2 antag

54

sxs fo serotonin syndrome

hyperthermia
confusion
myoclonus
cardiovascular instability
flushing
diarrhoea
seizures

55

lsit the snris please

venlafaxine, duloxetine

56

diabetic peripheral neupahty

duloxetine

57

moa of snris

inhibit Ne and 5Ht reuptake

58

ase of SNRIs

increased bp most common
stimulant effects
sedation
nausea

59

useds of venlafaxine

depression, GAD, panic disorder, PTSD

60

list the tcas please

amitriptyline, nortriptyline
imipramine, desipramiine, clomipramine
doxepin, amoxapine

61

moa of tca

block reuptae of Ne and 5ht

62

uses of tca

major depression
ocd - clomipramine
peripheral neuropathy
chronic pain
migraine prophylaxis

63

migraine prophylaxis

tcas

64

chronic pain

tcas

65

a/se of tcas

anti alpha 1
anti chloi
prolongation of qt itnerval

66

tca to use in elderly and why

nortriptyline bc less anticholis that would cause confusion and halluciations

67

how to prevent arrhythmia with tca use

naHCo3

68

serious a/se of tcas

coma
convulsions
cardiotoxicity
resp depression

69

NaHCO3

prevent arrhythmias in TCAs

70

list the MAOis please

MAO takes pride in changhai
tranylcypromine
phenelzine
isocarboxazid
selegiline

71

how is selegiline diff

selevite MAO B inhibitor

72

what is the moa of maois?

nonselectie MAO inhibition increases amine NT ie Ne, 5Ht, and Da

73

uses of MAOis

atypical depression
anxiety

74

a/se of maois

hypertensive crisis with tyramine
CNS stimulation

75

contraindicated at maois

cheese and wine - hypertensive crisis
serotonin syndrome - ssri, tca, st johsn wart, meperidine, dextromethorphan

76

use of buproprion

smoking cessation

77

moa of buproprion

increase ne and da with unknown moa

78

a/se of buproprion

stimulatnt - tach and insomnia
headache
seizures in anorexic/bulimic patients

79

what is buproprion godo for

no sexy time effects

80

moa of mirtazapine

inhibits alpha 2 -- increase Ne and 5HT release
5Ht2 and 5HT3 inhibitiors

81

uses of miertazapine

depression - want to sleep bc causes sedation
weight gain in elderly or anorexix (also causes increased appetite)

82

a/se fo miertazapine

sedation
weight gain
increased appetite
dry mouth

83

what is trazodone known for

priapism

84

moa of trazodone

blocsk 5HT2 and alpha 1

85

what is trazodone used for

insomina

86

a/se of trazodone

priapism
sedation
nausea
postural hypotension