Packet 28 Flashcards

1
Q

From fertilization to birth

A
fertilization
implantation
placental development
fetal development
gestation
labor
parturition (birth)
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2
Q

Haploid sperm nucleus & haploid secondary oocyte nucleus merge to form

A

single diploid nucleus

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3
Q

Occurs in uterine tube within 24 hours after ovulation (oocyte dies in 24 hours)

A

fertilization

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4
Q

events occurring before fertilization

A
  1. peristalsis of uterine tube and cilia transport oocyte to uterus
  2. sperm swims to oocyte by flagella
  3. capacitation (final maturation) of sperm occurs within female
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5
Q

sperm swim towards oocyte by means of flagella

—–stimulate uterine contractions that help move sperm towards the oocyte

A

prostaglandins

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6
Q

sperm penetrates the ___ cells around the oocyte

A

granulosa

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7
Q

Sperm digests its way throughthe

A

zona pellucida

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8
Q

First sperm to fuse with oocyte membrane triggers the slow & the fast block to

A

polyspermy

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9
Q

1-3 seconds after contact, oocyte membrane depolarizes & other cells can not fuse with it =

A

fast block to polyspermy

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10
Q

depolarization triggers the intracellular release of Ca+2 causing the exocytosis of molecules hardening the entire zona pellucida

A

slow block to polyspermy

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11
Q

Events within the egg

–sperm entry triggers___

A

oocyte to complete meiosis II and dump second polar body

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12
Q

Events within the egg

—Once inside the oocyte

A

the sperm loses its tail & becomes a male pronucleus

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13
Q

Events within the egg

—the true moment of fertilization is when

A

Fusion of male & female haploid pronuclei

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14
Q

fertilized ovum (2n) is called

A

zygote

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15
Q

Rapid mitotic cell division of embryo is called

A

cleavage

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16
Q

Formation of the morula

Day 1-4

A

Day 1. 1st cleavage in 30 hours produces 2 blastomeres

Day 2. 2nd cleavage on 2nd day

Day 3. By 3rd day has 16 cells

Day 4. By day 4 has formed a solidball of cells

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17
Q

By day 4 has formed a solidball of cells called

A

morula

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18
Q

is a hollow ball of cells that enters the uterine cavity by day 5

A

blastocyst

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19
Q

outer covering of cellscalled

A

trophoblast

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20
Q

fluid-filled cavity called

A

blastocele

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21
Q

Trophoblast & part of innercell mass will develop into

A

fetal portion of placenta

22
Q

most of the inner cell mass will become

A

the embryo

23
Q

Implantation consists of

A
  1. Attachment of blastocyst to endometrium
  2. Trophoblast develops 2 distinct layers
  3. Trophoblast secretes human chorionic gonadotropin
24
Q

occurs 6 days after fertilization

implants with inner cell mass in contact with the endometrium

A

attachment of blastocyst to endometrium

25
Trophoblast develops 2 distinct layers
1. syncytiotrophoblast | 2. cytotrophoblast
26
secretes enzymes that digest the endometrial cells
syncytiotrophoblast
27
distinct layer of cells that defines the original shape of the embryo
cytotrophoblast
28
secretes human chorionic gonadotropin (hCG) that helps the corpus luteum maintain the uterine lining
Trophoblast
29
Development of an embryo outside the uterus Most often in uterine tube --common causes are blockages of uterine tube such as tumors or scars from pelvic inflammatory disease --symptoms are missed menstrual cycles, bleeding & acute pain
ectopic pregnancy
30
ectopic pregnancy are twice as common in smokers because
nicotine paralyzes the cilia
31
Day 8 - cytotrophoblast forms - ectoderm & endoderm together form
amnion and amnionic cavity embryonic disk
32
cells of inner cell mass on amnionic cavity form
ectoderm
33
cells bordering on blastocele form
endoderm
34
endodermal cells divide to form a hollow sphere (yolk sac) cytotrophoblast cells divide to fill the spaces surrounding the yolk sac with extraembryonic mesoderm
Day 12
35
Day 14 | cells of embryonic disc produce 3 distinct layers
endoderm mesoderm ectoderm
36
forms epithelial lining of GI & respiratory
endoderm
37
forms muscle, bone & other connective tissues
mesoderm
38
develops into epidermis of skin & nervous system
ectoderm
39
Formation of Embryonic Membranes
Yolk sac amnion chorion allantois
40
site of early blood formation gives rise to gonadal stem cells (spermatogonia & oogonia)
Yolk sac
41
surrounds embryo with fluid: shock absorber, regulates body temperature & prevents adhesions fluid is filtrate of mother’s blood + fetal urine examine a sample of it for embryonic cells (amniocentesis)
Amnion
42
becomes the embryonic contribution to the placenta derived from trophoblast & mesoderm lining it gives rise to human chorionic gonadotropin (hCG)
Chorion
43
outpocketing off yolk sac that becomes umbilical cord
allantois
44
all of endometrium lost as placenta | --equals all of the endometrium, except stratum basalis
Decidua
45
portion of endometrium deep to chorion
Decidua basalis
46
part of endometrial wall that covers implanted embryo
Decidua capsularis-
47
part ofendometrial wall not modifiedby embryo until embryo bumps into it as it enlarges
Decidua parietalis-
48
Decidua capsularis fuses with
decidua parietalis
49
forms during 3rd month | chorion of embryo & stratum functionalis layer of uterus
Placenta
50
``` extend into maternal blood filled intervillous spaces --- maternal & fetal blood vessels do not join & blood does not mix --diffusion of O2, nutrients, wastes --stores nutrients & produces hormones --barrier to microorganisms, except some viruses -----AIDS, measles, chickenpox, poliomyelitis, encephalitis --not a barrier to drugs such as alcohol ```
Chorionic villi
51
contents of umbilical cord
1. 2 arteries that carry blood to the placenta 2. 1 umbilical vein that carries oxygenated blood to the fetus 3. primitive connective tissue
52
Stub drops off in 2 weeks leaving a scar called
umbilicus