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Flashcards in packet 10 Deck (21):
1

INNATE IMMUNITY
Immediate protection against wide variety of pathogens & foreign substances
lacks specific responses to specific invaders
Mechanisms function regardless of type of invader

nonspecific resistance to disease

2

Mechanisms function regardless of type of invader

external mechanical & chemical barriers
internal nonspecific defenses

3

internal nonspecific defenses

antimicrobial proteins
natural killer cells & phagocytes
inflammation & fever

4

skin (epidermis) closely packed, keratinized cells
shedding helps remove microbes
mucous membrane secretes viscous mucous
cilia & mucus trap & move microbes toward throat
washing action of tears, urine and saliva

mechanical protection

5

sebum inhibits growth bacteria & fungus
perspiration lysozymes breakdown bacterial cells
acidic pH of gastric juice and vaginal secretions destroys bacteria

chemical protection

6

Antimicrobial proteins that discourage microbial growth

interferons
complement proteins
transferrins

7

produced by virally infected lymphocytes & macrophages
diffuse to neighboring cells to induce synthesis of antiviral proteins

interferons

8

inactive proteins in blood plasma
when activated enhance immune, allergic & inflammatory reactions

complement proteins

9

iron-binding proteins inhibit bacterial growth by reducing available iron

transferrins

10

Abnormally high body temperature that occurs because the hypothalamic thermostat is reset
*occurs during infection and inflammation

fever

11

during fever the infection and inflammation allow for

bacterial toxins trigger release of fever-causing cytokines such as interleukin-1

12

intensifies effects of interferons, inhibits bacterial growth, speeds up tissue repair

benefit of fever

13

ingest microbes or particulate matter
macrophages developed from monocytes

Phagocytes (neutrophils & macrophages)

14

fixed macrophages stand guard in specific tissues
wandering macrophages in most tissue

macrophages developed from monocytes

15

help WBCs stick to endothelium

adhesion molecules

16

assist in movement through wall

molecules found in neutrophils

17

phagocytize bacteria & debris
chemotaxis of both
kinins from injury site & toxins

Neutrophils & macrophages

18

have a nucleus and no hemoglobin

ALL WBC (leukocytes)

19

classification based on presence of cytoplasmic granules made visible by staining

grandular and agrandular

20

neutrophils, eosinophils or basophils

grandulocytes

21

monocytes or lymphocytes

agrandulocytes