packet 7 Flashcards

(35 cards)

1
Q

Cells of the body are serviced by 2 fluids

A

blood

interstitial fluid

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2
Q

composed of plasma and a variety of cells

A

blood

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3
Q

bathes the cell of the body

A

interstitial fluid

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4
Q

Nutrients and oxygen diffuse from the blood into

A

interstitial fluid & then into the cells

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5
Q

function of blood

A

transportation
regulation
protection from disease and loss of blood

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6
Q

Transportation of

A

O2, CO2, metabolic wastes, nutrients, heat & hormones

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7
Q

helps regulate pH through buffers
helps regulate body temperature
coolant properties of water
vasodilatation of surface vessels dump heat
helps regulate water content of cells by interactions with dissolved ions and proteins

A

regulation

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8
Q
Thicker (more viscous) than water and flows more slowly than water
Temperature of 100.4 degrees F
pH 7.4 (7.35-7.45)
8 % of total body weight
Blood volume
5 to 6 liters in average male
4 to 5 liters in average female
hormonal negative feedback systems maintain constant blood volume and osmotic pressure
A

physical characteristics of blood

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9
Q

55% plasma
45% cells
**99%RBC
**

A

hematocrit

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10
Q

7% plasma protein
over 90% water
2% other substance

A

blood plasma

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11
Q

created in liver

confined to bloodstream

A

7% plasma proteins

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12
Q

intain blood osmotic pressure

A

albumin

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13
Q

antibodies bind to foreignsubstances called antigens

form antigen-antibody complexes

A

globulins (immunoglobulins)

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14
Q

for clotting

A

fibrinogen

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15
Q

Formed Elements of Blood

A

Red blood cells ( erythrocytes )
White blood cells ( leukocytes )
Platelets (special cell fragments)

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16
Q

Types of WBC’s

A

grandular leukocytes

agrandular leukocytes

17
Q

grandular leukocytes

A

neutrophils
eosinophils
basophils

18
Q

agrandular leukocytes

A

lymphocytes = T cells, B cells, and natural killer cells

monocytes

19
Q

38 - 46% (average of 42%)

40 - 54% (average of 46%)
testosterone

A

Percentage of blood occupied by cells

female
male

20
Q

not enough RBCs or not enough hemoglobin

21
Q

too many RBCs (over 65%)

dehydration, tissue hypoxia, blood doping in athletes

22
Q

formation of blood cells

A

Most blood cells types need to be continually replaced
In the embryo
in adult

23
Q

process of blood cells formation

A

hematopoiesis or hemopoiesis

24
Q

occurs in yolk sac, liver, spleen, thymus, lymph nodes & red bone marrow

A

formation of blood cells in embryo

25
occurs only in red marrow of flat bones like sternum, ribs, skull & pelvis and ends of long bones
formation of blood cells in adult
26
Contain oxygen-carrying protein hemoglobin that gives blood its red color 1/3 of cell’s weight is hemoglobin Biconcave disk 8 microns in diameter increased surface area/volume ratio flexible shape for narrow passages no nucleus or other organelles no cell division or mitochondrial ATP formation Normal RBC count male 5.4 million/drop ---- female 4.8 million/drop new RBCs enter circulation at 2 million/second
Red blood cells
27
Globin protein consisting of 4 polypeptide chains One heme pigment attached to each polypeptide chain each heme contains an iron ion (Fe+2) that can combine reversibly with one oxygen molecule (Fe = ferric + O = oxygen)
hemoglobin
28
Each hemoglobin molecule can carry 4 oxygen molecules from lungs to tissue cells Hemoglobin transports 23% of total CO2 waste from tissue cells to lungs for release Hemoglobin transports nitric oxide & super nitric oxide helping to regulate blood pressure iron ions pick up nitric oxide (NO) & super nitric oxide (SNO)& transport it to & from the lungs
Transport of O2, CO2 and Nitric Oxide
29
transported in blood attached to transferrin protein stored in liver, muscle or spleen attached to ferritin or hemosiderin protein in bone marrow being used for hemoglobin synthesis
Iron(Fe+3)
30
bilirubin secreted by liver into bile converted to urobilinogen then stercobilin (brown pigment in feces) by bacteria of large intestine if reabsorbed from intestines into blood is converted to a yellow pigment, urobilin and excreted in urine
biliverdin (green) converted to bilirubin (yellow)
31
high altitude since air has less O2 anemia RBC production falls below RBC destruction circulatory problems
Tissue hypoxia (cells not getting enough O2)
32
release erythropoietin | speeds up development of proerythroblasts into reticulocytes
Kidney response to hypoxia
33
Disc-shaped, 2 - 4 micron cell fragment with no nucleus Normal platelet count is 150,000-400,000/drop of blood Other blood cell counts 5 million red & 5-10,000 white blood cells
Platelet (Thrombocyte)
34
Short life span (5 to 9 days in bloodstream) formed in bone marrow few days in circulating blood aged ones removed by fixed macrophages in liver and spleen
Platelets--Life History
35
Screens for anemia and infection – components measured? Total RBC, WBC & platelet counts; differential WBC; hematocrit and hemoglobin measurements Normal hemoglobin range infants have 14 to 20 g/100mL of blood adult females have 12 to 16 g/100mL of blood adult males have 13.5 to 18g/100mL of blood
complete blood count