passmed

Question 1

what is seen in MEN 1

Answer 1

• parathyroid (hyperparathyroidism)
• pituitary
• pancreas (insulinomas, gastrinoma)

most common presentation is hypercalcaemia

Question 2

if there is low potassium what does this mean about the aldosterone levels

Answer 2

they are HIGH

Question 3

resp features of GPA

Answer 3

• haemoptysis
• pulmonary infiltrates
• alveolar haemorrhage
• cavitating nodules on CXR

Question 4

is club foot passively correctable

Answer 4

no

Question 5

causes of dactylitis

inflammation of one digit

Answer 5

• psoriatic and reactive arthritis
• sickle cell disease
• TB, sarcoid, syphilis

Question 6

what can tenderness over the tibia indicate

Answer 6

a stress fracture

Question 7

positive lachman test

Answer 7

ACL rupture

Question 8

side effect of bisphosphonates

Answer 8

osteonecrosis of the jaw

Question 9

do prolactinomas cause fertility problems

Answer 9

yes

Question 10

side effect of immunosuppressants (azathioprine)

Answer 10

myelosuppression

Question 11

how long should antibiotics be prescribed in septic arthritis

Answer 11

4-6 weeks

Question 12

if a hip dislocation presents with a clunk, what type of dislocation is it most likely to be

Answer 12

posterior

Question 13

foot pain exacerbated by walking on tip toes

Answer 13

plantar fasciitis

Question 14

treatment of nephrogenic diabetes insipidus

Answer 14

thiazide diuretics

Question 15

thiazide diuretic effects on sodium and potassium levels

Answer 15

results in sodium and potassium excretion

Question 16

treatment of nephrotic syndrome

Answer 16

corticosteroids

Question 17

what disease is pyoderma gangrenosum associated wtih

Answer 17

Crohns

Question 18

which MEN causes phaeochromocytoma

Answer 18

2a and 2b

Question 19

swelling where is a feature of sjogren syndrome

Answer 19

parotid

Question 20

what is a basal bolus insulin regime

Answer 20

take long acting once a day and then short acting at meal times

Question 21

what causes guttate psoriasis

Answer 21

strep infection

usually in children

Question 22

what antibodies for pemphigus vulgaris

Answer 22

IgG autoantibodies against desmosomes

Question 23

what is seen on immunofluouresence in pemphigus vulgaris

Answer 23

circular intra-epidermal deposits

Question 24

first line investigation for acromegaly

Answer 24

IGF-1 levels

Question 25

can diabetes cause erectile dysfunction

Answer 25

yes | -autonomic neuropathy

Question 26

what virus is seborrhoeic dermatitis associated with

Answer 26

HIV

Question 27

which men presents with medullary thyroid cancer

Answer 27

MEN 2a

Question 28

triggers of shingles

Answer 28

- malignancy - stress - systemic infection - immunocompromised patients

Question 29

what is the management for de quervain's thyroiditis

Answer 29

analgesia (naproxen)

Question 30

joint aspirate results in rheumatoid arthritis

Answer 30

WBCs

Question 31

what cancer is hashimotos associated with

Answer 31

MALT lymphoma

Question 32

which diabetic drugs increase insulin sensitivity

Answer 32

thiazolidinediones

Question 33

if a post menopausal woman has a fracture, what should she be put on

Answer 33

bisphosphonate and calcium supplementation

Question 34

if urine osmolality is high after water deprivation and desmopressin what does this mean

Answer 34

primary polydispia (psychogenic)

Question 35

what is required for an asymptomatic patient to be diagnosed with type 2 diabetes

Answer 35

two abnormal hbA1c readings

Question 36

can acromegaly cause galactorrhea

Answer 36

yes

Question 37

investigation for phaeochromocytoma

Answer 37

plasma and urinary metanephrines

Question 38

thyroid results in pregnancy

Answer 38

raised T3, T4 normal TSH normal fT3, fT4

Question 39

blood results for kleinfelters

Answer 39

- low testosterone - high LH - high FSH

Question 40

blood results for kallmanns

Answer 40

- testosterone low - LH low/normal - FSH low/normal

Question 41

most common cause of hyperparathyroidism

Answer 41

adenoma

Question 42

what is a complication of fluid resus in DKA

Answer 42

cerebral oedema | -can cause seizures

Question 43

what is the PTH level in hypercalcaemia secondary to malignancy

Answer 43

low | -PTHrP may be raised

Question 44

pepperpot skull appearance

Answer 44

primary hyperparathyroidism

Question 45

side effect of carbimazole

Answer 45

AGRANULOCYTOSIS | mentioned in revision event !!!

Question 46

what does rapidly progressive GN look like on renal biopsy

Answer 46

crescentic GN

Question 47

what do kimmelstiel wilson nodules indicate

Answer 47

diabetic nephropathy

Question 48

total thyroxine levels (T4) in nephrotic syndrome

Answer 48

may be low

Question 49

is furosemide safe to use in AKI

Answer 49

no

Question 50

is warfarin safe to use in AKI

Answer 50

yes

Question 51

side effect of statins

Answer 51

rhabdomyolysis

Question 52

complication of nephrotic syndrome

Answer 52

predispose to thrombosis

Question 53

side effect of fluid resus requiring large volumes

Answer 53

hyperchloraemic metabolic acidosis

Question 54

what should you give to patients with newly diagnosed CKD

Answer 54

ACEi and a statin