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Year 2 Semester 2 > Pathology > Flashcards

Flashcards in Pathology Deck (311)
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301

Which lab tests can we do to test the intrinsic pathway?

PTT, ACT (more letters for more factors)

302

Which lab tests can we do to test the extrinsic pathway?

PT (less letters for less factors)

303

Which lab tests can we do to test the common pathway?

PTT, ACT, PT
TT

304

Name some natural anticoagulants

Intact endothelium
Protein C
Antithrombin III

305

What does antithrombin III limit?

Fibrin formation
Inhibits thrombin

306

What can you measure that is evidence of fibrinolysis?

FDPs
(Fibrin Degradation Products)

307

What is the difference between labile, stable and permanent cells?

Labile= continuously dividing eg epidermis
Stable= low levels of replication (G0), however, in response to stimuli undergo rapid division (G1) eg hepatocytes
Permanent= non-dividing eg neurones

308

What is the difference between agenesis and aplasia?

Agenesis= absence of an organ or body part- no associated primordium (first trace of a structure)
Aplasia= failure of an organ to develop

309

What is the difference between benign and malignant tumours?

Benign= tumour remains localised and cannot spread. Slow growth.
Malignant= can invade and destroy adjacent structures and spread to different sites (metastasis) to cause death. Fast growth

310

What do the suffix's -oma and -sarcoma mean?

-oma = benign tumour
-sarcoma = malignant mesenchymal tumour (bigger and badder)
-carcinoma = malignant epithelial tumour

311

What is the difference between gram-positive and gram-negative bacteria?

Gram-negative have an outer membrane but gram-positive don't