Pharm 5 Flashcards

(61 cards)

1
Q

empiric

A

best guess based on history

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2
Q

resistance to drugs

A

frequent use

incomplete treatment

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3
Q

selection of anti-infective drugs

A
site of the infection
status of hepatic/renal failure
age
pregnancy
likelihood of develop resistance
known allergy
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4
Q

allergic hypersensitivtiy

A

over response of the body to a specific substance

mild: rash

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5
Q

anaphylaxis

A

severe reaction

dyspnea, chest constriction, shock

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6
Q

direct toxicity

A

results in tissue damage

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7
Q

indirect toxicity (superinfection)

A

new infection as a result of killing the normal flora

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8
Q

CDC recommendations

A

routine vaccines

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9
Q

aminoglycosides

A

treat gram - (E. Coli). gram + (Staph.)

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10
Q

treatment of septicemia

A

aminoglycosides

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11
Q

septicemia

A

bacteria in the bloodstream causing very low blood pressure

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12
Q

aminoglycosides side effects

A

nephrotoxicity

ototoxicity

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13
Q

cephalosporins

A

beta lactam antibiotic derivatives produced by a fungus BROAD

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14
Q

1st generation

A

UTI’s

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15
Q

2nd generation

A

bacterial pneumonia

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16
Q

3rd generation

A

STI’s

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17
Q

5th generation

A

acute bacterial skin

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18
Q

cephalosporins side effects

A

hypersensitiity

blood dyscrasias

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19
Q

macrolides

A

treatment of infections of the respiratory tract PREFFERED

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20
Q

macrolides side effects

A

superinfections

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21
Q

penicillins

A

treat strep. and staph. infections

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22
Q

drug of choice for syphilis

A

penicillin

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23
Q

prevent fevers

A

penicillin

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24
Q

penicillins side effects

A

superinfections

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25
carbapenems
beta lactam class of antiiotics
26
carbapenems treatment
pneumonia BROAD
27
quinolones
adult UTI's
28
quinolones side effects
phototoxicity | cartilage or tendon damage
29
tetrcyclines
treat infections caused by rickettsia, chlamydia BROAD
30
tetracyclines side effects
discolored teeth in young children
31
amphotericin B
administered by IV for fatal infections
32
drug of choice fore severe fungal infections
amphotericin
33
amphotericin side effects
watch closer since severe
34
fluconazole
antifungal agent treatment of oropharyngeal and esophageal candidiasis
35
fluconazole side effects
hepatic abnormalities
36
antifungals
treat fungal disease
37
micafungin
newer classes of antifungals IV
38
micafungin treatment
esophageal candidiasis and aspergillus
39
micafungin side effects
neutropenia
40
nystatin
orally teat oral cavity candidiasis
41
clindamycin
serious respiratory tract infections, septemia
42
metronidazole
treatment for amebiasis and giardiasis
43
metronidazole side effect
dark urine
44
vancomycin
drug of choice for MRSA
45
last line of defense
vancomycin for staph.
46
linezolid
gram + infections | VRE VRSA
47
diabetic foot infections
linezolid
48
sulfonamides
oldest anti infectives | good when put with other drugs; less resistance then
49
sulfonamides side effects
hepatic toxicity | renal damage
50
UTI
most common | microorganisms in the urinary tract
51
sulfamethoxazole trimethoprim and nitrofurantoin
first line urinary anti infectives for empiric treatment
52
UTI side effects
dark yellow urine
53
acyclovir
treat herpes simplex, shingles, and chickenpox
54
acyclovir side effects
lethargy | tremors
55
neuraminidase inhibitors
treatment of uncomplicated illness due to influenza A and B
56
neuraminidase inhibitors
airway irriation since it is done by inhalation
57
ribavirin
BROAD | treatment of children with respiratory syncytial virus infections
58
macrolides preferred
least toxic and preferred for pregnant women or infants
59
poses greater risk for superinfection
tetracyclines
60
cephalosporins bad
alcohol
61
related to penicillins
cephalosporins