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Flashcards in pharm 7 Deck (43):
1

endocrine

hormones produced by a ductless gland that secretes directly into the bloodstream

2

hormones

chemical messengers that have specialized functions in regulating the activities

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master gland

pituitary gland

4

pituitary gland

regulates the function of the other glands

5

somatotropin (human growth hormone)

regulates growth

6

adrenocorticotropic hormone (ACTH)

diagnosis of adrenocrtical insufficiency

7

cortrosyn

synthetic peptide of ACTH
used for diagnosis of adrenocortical insufficiency

8

adrenal glands

secrete cortiosteroids

9

corticosteroids

act on the immune system to suppress the body's response to infection or trauma

10

2 categories of corticosteroids

replacement therapy
anti inflammatory

11

some conditions corticosteroids treat

allergic reactions
COPD
skin conditions

12

long term use of cortiocosteroids

suppression of the pituitary gland

13

cortiocosteroid SE

ORGAN TRANSPLANT
delayed wound healing
osteoporosis
cushings syndrome

14

thyroid

regulating the rate of metabolism

15

hypothyroidism

most common thyroid problem

16

thyroid preparations

replacement therapy for hypothyroidism

17

antithyroid agents

relieve hyperthroidism symptoms for surgery

18

antithyroid example

methimazole (treatment of choice)

19

diabetes mellitus

impaired metablism

20

type 1

destruction of pancreatic beta cells

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type 2

characterized by insulin resistance and deficiency

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juvenile diabetes

type 1

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most common diabetes

types 2

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when is insulin required?

type 1

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how is insulin given?

sub q

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hyperglycemia

elevated blood glucose

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hypoglycemia

lower blood glucose

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what do sulfonylureas do?

increase insulin production and activity

29

alpha gluosidase inhibitors

delay digestion of complex carbs

30

biguanides

decrease hepatic glucose production and enhance insulin uptake in muscle tissue

31

metformin

preferred initial first line monotherapy (biguanides)

32

incretin therapies

mimic actions of incretin hormones (may be benefical)

33

example of incretin therapies

januvia

34

meglitinides

rapid onset and short duration of action

35

what do meglitinides do?

produce insulin

36

thiazolidinediones example

actos

37

thiazolidinediones

lower blood glucose

38

how should you stop corticosteroids?

taper or step down gradually

39

cretinism

congenital
requires treatment to prevent mental retardation

40

hyperthyroid

caused by graves disease

41

lantus

long acting insulin

42

hyperglycemia treatment

IV fluids

43

hypoglycemia treatment

sugary drink and then protein