Pharm2Sulf/FQ Flashcards Preview

Pharmacology > Pharm2Sulf/FQ > Flashcards

Flashcards in Pharm2Sulf/FQ Deck (20):
1

sulf:
SOA:
s/e: ?uria, hypersensitivity, ? in newborns, drug potentiation from ?

G+&-
crystal, kernicterus, albumin displacement

2

aka pediazole; otitis media (H flu) in peds

erythro (ESP) & sulfasoxazole

3

UTIs, RTIs, gastroenteritis, PCP***

sulfamethoxazole-trimethroprim

4

toxoplasmosis; give w/

sulfadiazine & pyramethamine; folinic acid

5

broken down to 5-aminosalicylate; Tx IBD?

sulfasalazine (PO or suppository)

6

topical for eye and skin infx, acne

sulfacetamide

7

Tx burns, prevent sepsis

silver sulfadiazine

8

-much more potent than sulfa's, analog of dihydrofolic acid; UTIs & bacterial prostatitis?
-inhibits ? (second step in FA sun
-s/e?; reverse w/?

trimethroprim
dihydrofolate reductase
granulocytopenia, leukopenia, megaloblastic anemia; folinic acid

9

-1st line haem (otitis, sinusitis, pneumonia, chancroid), moraxella (same but not chancroid), enterobacter>>> think RTIS in ?
-Tx gastroenteritis (salmonella, shigella)
-DOC for ?
-OK in ???

SMX-TMP aka cotrimoxazole, PEDS
nocardiosis, PCP
CHILDREN

10

FQ will treat IC bc it accumulates in ? and ?

macrophages, PMNs

11

FQ resistance: (2)

altered target site
decreased accumulation

12

-Tx UTIs, prostatitis (E coli, enterobacter); FQ w/ most clinical apps;
primarily gram ned aerobes
-pseudomonas associated with ?
-also shigella, salmonella, campylobacter, vibrio

cipro
cystic fibrosis

13

best bioavailability, best FQ for chlamydia trachomatis urethritis?

ofloxacin

14

most commonly Rx'ed FQ?
G+ activity against? (4)

levo
staph a., s pneumo, strept pyo, MDRSP

15

FQ- Tx only bronchitis and pneum (aka RTIs)

gemifloxacin

16

G4 FQ advantage- active against?
Tx MDRSP, skin, RTIs?
Tx- eye drops ONLY in bad conj?

anaerobes
moxifloxacin- widest spectrum FQ
gatifloxacin

17

s/e FQ (4)

ruptured achilles tendon
prolonged QT
phototoxicity
nephrotoxicity

18

FQ CI in ? and ? bc of ?

pregnancy, under 18, articular cartilage erosion

19

urine a/b - turns urine brown?
CI in ?
active against E coli, staph saprophytic us
prevents recurrent ? from UTIs in females

nitrofurantoin
pregnancy
cystitis

20

methenamine mandelate/hippurate:
-decomposed at acidic pH into ? and provides ? effect
-in combo w/?

formaldehyde
antiseptic
sulfonamide