Flashcards in Pharm2CWI Deck (12):
empiric tx - 2
carbapenems resistant to most?
penem that tx various nosocomial infx from serrate, actinobacter?
imipenem (w/ cilastatin b/c it is hydrolyzed by renal dehydropeptidase to nephrotoxic metabolite)
penem that may cause seizures?
imipenem (broadest b lactam on market)
no ? activity, only ?
UTIs, RTIs, nosocomial
G + activity, G - aerobic
Bacitracin - CWI
topical ONLY, systemic can lead to ?
skin, ocular w/ ?
neomycin, polymixin B
w/ ? for synergism
DOC/1st line for ? (3)
*only oral for c diff; rest are slow IV b/c of flushing, shock, etc.; can also have ??
tetanus, pen-resistant s. pneumo, MRSA
gramcidin- membrane disruptor
replaces bacitracin in combo with ? and ? for ocular infix?
G + cocci, bacilli
polymixin B, neosporin
daptomycin- depolarizes membrane potential
is considered a cyclic ?
MDRSP VRSA MRSA VRE endocarditis bacteremia
SINGLE dose to treat?
safe & used in ?
commonly UTI in female
2nd line TB; bacterioSTATIC
s/e: ? toxicity, ? neuropathies
CNS- CROSSES BBB, peripheral