Phys: Respiratory Phys Flashcards Preview

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Flashcards in Phys: Respiratory Phys Deck (33)
1

fxn of lungs?

gaseous exchange
pH balance

2

what is gaseous exchange dependent on?

ventilation- amount of gas delivered by the lungs
perfusion- amount of blood delivered by the heart to the lungs
diffusion- amount of gas that passes thru the air-blood barrier

3

perfusion is greatest?

base- wasted perfusion

4

ventilation is highest?

apex- wasted ventilation

5

air- blood barrier is made up of?

capillary endothelium, basement membrane, type I pneumocyte

6

what are type II pneumocyte fxn?

make the surfactant, which reduces the surface tension in the alveoli

7

what is ficks law?

rate of diffusion through a membrane is inversely proportional to the thickness of the membrane

8

ventilation/perfusion rate is?pulmonary BF rate is?

4 L/min; 5 L/min- 4L/5L=0.8
highest is Apex -3
lowest in Base - 0.6

9

what is meant by "a shift to the right" regarding oxygen

decrease Hb affinity for O2, therefore O2 is released

10

what are the 4 factors for a shift to the right

acidosis
CO2 increase
temp inc
2,3 DPG

11

97% of the oxygen in blood is carried by?

hemoglobin

12

CO2 is transported by?

70% bicarbonate
23% attached to hhemoglobin as cardaminohemoglobin
7% dissolved in plasma

13

what does lipoprotein do?

keeps lung exoanded by dec surface tension

14

what is partial pressure?

O2 conc. in the alveoli
controlled by:
rate of absorption of O2 in blood
rate of entry of new O2 into lungs bu breathing

15

on inspiration the diaphragm does what?

contracts
when pressure dec. - air moves into lungs

16

TV is?

tidal volume
500 mL
volume of a normal breath

17

IRV is?

inspiratory reserve volume
3100 mL
volume inspired above TV

18

ERV is?

expiratory reserve volume
1200 mL
volume expired after normal breath

19

RV is?

residual volume
1200 mL
what resides in the lungs

20

IC is?

inspiratory capacity
3600 mL
IRV+TV=IC

21

FRC is?

functional resdiual capacity
2400 mL
air left in lungs after normal expiration
ERV+TV=FRC

22

VC is?

Vital capacity
4800 mL
volume expired after maximal inspiration
ERV+IRV+TV=VC

23

TLC is?

total lung capacity
5-6 L
IRV+ERV+TV+RV=TLC

24

pneumotaxic center does?

turns off inspiratory center before overexpansion of lungs occur

25

herring -breuer reflex is?

stretch receptors- bronchi PREVENT over stretching of lungs

26

apneustic center does?

prevents turn off of inspiratory center

27

Bohr effect is?

CO2 enters blood stream, causing O2 disassociation from hemoglobin

28

haldene effect does?

CO2 combines with hemoglobin to form more bicarbonate ions

29

what is the major determinant of breathing?

conc. of CO2 in the blood

30

arterial Pco2=?

40 mmHg

31

Cheyne-stokes breathing is?

periods of rapid breathing w/ increasing then decreasing TV followed by apnea (seen in CHF)

32

Kussmaul breathing is?

deep rapid regular breathing
diabetic ketoacidosis

33

Biot's respiration is?

bouts of irregularly irregular breathing and apnea
brain stem compression