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Flashcards in Path: MS system Deck (40)
1

Osteitis deformans aka? S/S? Lab?

pagets
older males, mosaic layers, bowing tibia, IVORY WHITE VERTEBRA, pseudofractures,
Lab: increased alkaline phosphatase 40 times higher

2

Neurofibromatosis aka?

von recklinghausens disease
genetic
coast of maine café au lait spots
can compress nerves

3

fibrous dysplasia is?

bone thinning, lesions, growth in bone.
monostotic= one bone
polyostsotic= many bones

4

mccune-albrights disease

found in young girls, several bones involved, endocrine related

5

hemangioma

MC benign bone tumor of the vertebra
affects only one level

6

osteochondroma

MC benign bone tumor of the body
sessile- no stalk
peduncle- stalk

7

osteogensis imperfecta

brittle bone disease
genetic
abnormal collagen
fractures
BLUE sclera

8

OsteopEtrosis

overgrowth & sclerosis bone, however is weak & fractures

9

osetopOrosis

post menopausal
increases fractures
Dowager hump

10

osteomyelitis

Staph infection in bone

11

Potts disease

TB of the spine
spreads lungs> thoracics> eats the joints> vertebra collapses> inc. kyphosis
causes Gibbus deformity

12

Avulsion fracture

ligament pulls away part of bone

13

comminuted fracture

has many fragments

14

Compound fracture

protrusion through the skin

15

simple fracture

no protrusion through the skin

16

avascular necrosis

aka AVN, ischemic necrosis, aseptic necrosis, osteochondrosis

17

Osgood schlatter's

tibial tuberosity AVN, 13-16 y/o

18

leg calve perthes

femoral head AVN, 4-8 y/o

19

Osteoathritis

aka DJD, degenerative joint disease
narrowing joint spaces
subchondral sclerosis
osteobalstic activity
-asymmetrical
-repetitive- response to stress
-weight bearing joints

20

rheumatoid arthritis

females 20-40 autoimmune
symmetrical
pannus formation
ulnar deviation
inflammation of synovium
affects limbs & cervicals
morning stiffness

21

Fettys syndrome

long standing RA, hepatomegaly, splenomegaly

22

juvenile RA

stills disease

23

Labs RA

RA latex
sero +

24

Caplans

RA + pneumonia

25

Reiters

reactive arthritis
adult male; STD, chlamydia
feet & spine conjunctivitis
urethritis & arthritis (heel Spur)
"lovers heal"- calcaneal spur
"cant see, cant pee, cant dance with me"

26

Charcot joint

aka neurogenic joint
6 D's
debris
dysfunction
deformity
dislocation
destructive
distention
disease
posterior column destruction, diabetes mellitus (feet), syringomyelia (shoulder)

27

psoriatic

ray sign- pencil in cup deformity in phalanx
destroys joint- mouse ears
70% skin
30% arthritis
-silver scales
- pitted nails

28

Gout

-initially starts inside the joint
- attacks small joints
MC big toe - podagra
tophi
destruction around the joint
purine metabolism problem
uric acid crystal build up

29

pseudogout aka CPPD

big joints
knee
calcium pyrophosphate crystals

30

ankylosing spondylitis

aka Marie strumpell
symmetrical- loves the pelvis- starts in SI joints
young males, poker or bamboo spine
makes the spine rigid
HLA-B27
sero -
breathing difficulties
trolley track, dagger sign, shiny corner

31

DISH- Diffuse idiopathic skeletal hyperostosis

aka Forestiers disease
over 50 y/o
all CALCIFICATION
cervical pain
stiffness, dec. ROM
affects cervical
assoc with diabetes
Facets are not fused

32

Erb-duchennes MD

0-12 boys
autosomal recessive
severe-fatal
pseudohypertrophy of calf muscles
increased CPK 300 times
x-linked
gower sign

33

Becker MD

10-70 y/o
autosomal recessive
mild
pelvis & legs

34

fascioscapulohumeral dystrophy

10-20 y/o
autosomal DOMinant
mild
face & shoulders

35

Guillain-Barre

acute polyneuropathy
polyradiculuitis
following surgery or immunization
ASCENDING paralysis

36

Myasthenia gravis

female
myoneural junction
decrease Ach receptors especially the cranial nerves
ptosis
diplopia
eyes are effected first

37

lambert eaton

inhibit Ca++
older women
common with small cell carcinoma
increased contractions with repeated stimuli

38

Charcot-marie-tooth

autosomal disease
onset in childhood
horrible calf pain- calf muscle atrophy
demyelination

39

Ehlers- Danlos syndrome

autosomal dominant
hyperextensible skin & joints
large artery
fragile

40

McArdles

30-40 year old
myalgia
early fatigue
painful cramps
weakness of excercising muscles