Path: MS system

Question 1

Osteitis deformans aka? S/S? Lab?

Answer 1

pagets
older males, mosaic layers, bowing tibia, IVORY WHITE VERTEBRA, pseudofractures,
Lab: increased alkaline phosphatase 40 times higher

Question 2

Neurofibromatosis aka?

Answer 2

von recklinghausens disease
genetic
coast of maine café au lait spots
can compress nerves

Question 3

fibrous dysplasia is?

Answer 3

bone thinning, lesions, growth in bone.
monostotic= one bone
polyostsotic= many bones

Question 4

mccune-albrights disease

Answer 4

found in young girls, several bones involved, endocrine related

Question 5

hemangioma

Answer 5

MC benign bone tumor of the vertebra

affects only one level

Question 6

osteochondroma

Answer 6

MC benign bone tumor of the body
sessile- no stalk
peduncle- stalk

Question 7

osteogensis imperfecta

Answer 7

brittle bone disease
genetic
abnormal collagen
fractures
BLUE sclera

Question 8

OsteopEtrosis

Answer 8

overgrowth & sclerosis bone, however is weak & fractures

Question 9

osetopOrosis

Answer 9

post menopausal
increases fractures
Dowager hump

Question 10

osteomyelitis

Answer 10

Staph infection in bone

Question 11

Potts disease

Answer 11

TB of the spine
spreads lungs> thoracics> eats the joints> vertebra collapses> inc. kyphosis
causes Gibbus deformity

Question 12

Avulsion fracture

Answer 12

ligament pulls away part of bone

Question 13

comminuted fracture

Answer 13

has many fragments

Question 14

Compound fracture

Answer 14

protrusion through the skin

Question 15

simple fracture

Answer 15

no protrusion through the skin

Question 16

avascular necrosis

Answer 16

aka AVN, ischemic necrosis, aseptic necrosis, osteochondrosis

Question 17

Osgood schlatter’s

Answer 17

tibial tuberosity AVN, 13-16 y/o

Question 18

leg calve perthes

Answer 18

femoral head AVN, 4-8 y/o

Question 19

Osteoathritis

Answer 19

aka DJD, degenerative joint disease
narrowing joint spaces
subchondral sclerosis
osteobalstic activity
-asymmetrical
-repetitive- response to stress
-weight bearing joints

Question 20

rheumatoid arthritis

Answer 20

females 20-40 autoimmune
symmetrical
pannus formation
ulnar deviation
inflammation of synovium
affects limbs & cervicals
morning stiffness

Question 21

Fettys syndrome

Answer 21

long standing RA, hepatomegaly, splenomegaly

Question 22

juvenile RA

Answer 22

stills disease

Question 23

Labs RA

Answer 23

RA latex

sero +

Question 24

Caplans

Answer 24

RA + pneumonia

Question 25

Reiters

Answer 25

``` reactive arthritis adult male; STD, chlamydia feet & spine conjunctivitis urethritis & arthritis (heel Spur) "lovers heal"- calcaneal spur "cant see, cant pee, cant dance with me" ```

Question 26

Charcot joint

Answer 26

``` aka neurogenic joint 6 D's debris dysfunction deformity dislocation destructive distention disease posterior column destruction, diabetes mellitus (feet), syringomyelia (shoulder) ```

Question 27

psoriatic

Answer 27

``` ray sign- pencil in cup deformity in phalanx destroys joint- mouse ears 70% skin 30% arthritis -silver scales - pitted nails ```

Question 28

Gout

Answer 28

-initially starts inside the joint - attacks small joints MC big toe - podagra tophi destruction around the joint purine metabolism problem uric acid crystal build up

Question 29

pseudogout aka CPPD

Answer 29

big joints knee calcium pyrophosphate crystals

Question 30

ankylosing spondylitis

Answer 30

``` aka Marie strumpell symmetrical- loves the pelvis- starts in SI joints young males, poker or bamboo spine makes the spine rigid HLA-B27 sero - breathing difficulties trolley track, dagger sign, shiny corner ```

Question 31

DISH- Diffuse idiopathic skeletal hyperostosis

Answer 31

``` aka Forestiers disease over 50 y/o all CALCIFICATION cervical pain stiffness, dec. ROM affects cervical assoc with diabetes Facets are not fused ```

Question 32

Erb-duchennes MD

Answer 32

``` 0-12 boys autosomal recessive severe-fatal pseudohypertrophy of calf muscles increased CPK 300 times x-linked gower sign ```

Question 33

Becker MD

Answer 33

10-70 y/o autosomal recessive mild pelvis & legs

Question 34

fascioscapulohumeral dystrophy

Answer 34

10-20 y/o autosomal DOMinant mild face & shoulders

Question 35

Guillain-Barre

Answer 35

acute polyneuropathy polyradiculuitis following surgery or immunization ASCENDING paralysis

Question 36

Myasthenia gravis

Answer 36

``` female myoneural junction decrease Ach receptors especially the cranial nerves ptosis diplopia eyes are effected first ```

Question 37

lambert eaton

Answer 37

inhibit Ca++ older women common with small cell carcinoma increased contractions with repeated stimuli

Question 38

Charcot-marie-tooth

Answer 38

autosomal disease onset in childhood horrible calf pain- calf muscle atrophy demyelination

Question 39

Ehlers- Danlos syndrome

Answer 39

autosomal dominant hyperextensible skin & joints large artery fragile

Question 40

McArdles

Answer 40

``` 30-40 year old myalgia early fatigue painful cramps weakness of excercising muscles ```