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Psych Pharm Flashcards

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1
Q

Preferred drug: EtOH withdrawal?

A

Benzos

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2
Q

Preferred drug: anxiety

A

SSRI, SNRIs, buspirone

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3
Q

Preferred drug: ADHD

A

Methylphenidate, amphetamine

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4
Q

Preferred drug: bipolar

A

lithium, valproate, carbamazepine

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5
Q

Preferred drug: bulemia

A

SSRI

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6
Q

Preferred drug: depression

A

SSRI, SNRI, TCA, buspirone

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7
Q

Preferred drug: depression with insomnia

A

mirtazapine

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8
Q

Preferred drug: OCD

A

SSRI, clomipramine

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9
Q

Preferred drug: Panic disorder

A

SSRIs, venlafaxine, benzos

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10
Q

Preferred drug: PTSD

A

SSRIs

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11
Q

Preferred drug: social phobias?

A

SSRIs

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12
Q

Preferred drug: tourette’s

A

haloperidol, risperidone

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13
Q

Drugs that increase catecholamines at synaptic cleft, esp DA and NE. Use?

A

Methylphenidate, dextroamphetamine, methamphetamine. ADHD, narcolepsy, appetite control

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14
Q

Pt wants to control appetite. Can give?

A

Methylphenidate, -amphetamines

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15
Q

MoA of antipsychotics?

A

Haloperidol and -azines. Block D2 receptors, increasing cAMP.

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16
Q

Side effects of high potency antipsychotics?

A

Trifluoperazine, Fluphenazine, Haloperidol (Try to Fly High). Extrapyramidal symptoms Dyskinesias etc)

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17
Q

Side effects of low potenncy antipsychotics?

A

Chlorpromazine, thioridazine. (Cheating theives are low). Anticholinergic, antihistamine, a1-block

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18
Q

Antiphychotic treat what type of schizophrenia symptoms?

A

postive

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19
Q

Side effect in female schizophrenic treated with antipsychotic?

A

Galactorrhea (decreased DA -> more prolactin)

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20
Q

Pt comes in with a slowly developing rigidity, myoglobinema, and fever, encephalopathy. Cause? Treat with?

A

Neuroletic malignant syndrome. Dantrolene and D2 ags (bromocriptine)

NMS: FEVER
Fever, encephalopathy, unstable vitals, elevated enzymes, rigidity of muscles

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21
Q

Pt with well controlled, long term phychosis comes in with stereotypic oral-facial movements. From what drug?

A

tardive dyskinesia from high potency antipsychotics.

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22
Q

Evolution of EPS side effects?

A

4 hr dystonia
4 day akathisia (restlessness)
4 wk bradykinesia
4 mo tardive dyskinesia

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23
Q

Atypical antipsychotics

A

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
(Its atypical for OLd CLOSets, to QUIETly RISPER from A to Z)

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24
Q

Corneal deposits, side effect of what antipsychotic? Retinal deposits?

A

Chloropromazine, Thioridazine

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25
Drugs that have various effects on 5HT2, DA, a-ad, and H1 recptors - used for?
Schizo (both + and - symptoms) | Bipolar, OCD, anxiety, depression, mania
26
Atypical that may cause weight gain?
Clozapine and olanzapine
27
Atypical that needs to be monitored weekly?
Clozapine - agranulocytosis. Watch clozapine closely
28
Atypical that may prolong QT?
Ziprasidone
29
Psych drug used for SIADH
Lithium
30
Side effects of Lithium?
``` LMNOP Lithium Movement (tremor) Nephrogenic diabetes insipidus HypOthyroidism Pregnancy Problems ```
31
Pregnant women takes lithium. risk of
Ebstein's anomaly (tricuspid problem( and malformation of great vessels
32
Problem with lithium
narrow therapeutic window
33
Li excreted by? (most is resorbed where?)
kidney; PCT with Na
34
Pt comes in with heart block and polyuria - what psych drug is she on?
Li
35
MoA of drug for GAD that does not interact with alcohol
Buspirone. Stimulates 5HT1a. Anxiously waiting for the BUS
36
SSRIs?
Fluoxetine, paroxetine, sertraline, citalopram Flashbacks paralyze senior citizens
37
Pt comes in complaining SSRI isn't working. Say?
wait 8 weeks
38
Pt comes in with rapid onset fever, confusion, myoclonus and heart problems. Drugs that caused it? MoA of drug that can Tx?
Serotonin syndrome (MAOIs, SSRIs, SNRIs), Tx with cyproheptadine, 5HT2 antag
39
depressed Pt had too many side effects on drug. Replaced with another drug that alleviated most effect but caused anorgasmia.
SSRI, fewer side effects than TCAs, but anorgasma
40
SNRIs
Venlafaxine and duloxetine
41
Used in panic disorders and GAD?
Venlafaxine
42
psych drug used for diabetic perpheral neuropathy?
Duloxetine
43
SNRI with greater effect on NE?
Duloxetine
44
Pt comes in with increased BP, nausea and sedation. Side effect of?
SNRIs
45
TCA - suffixes and exceptions?
-iptyline and -ipramine | except doxepin and amoxapine
46
TCA for bedwetting
imipramine
47
TCA for OCD
clomipramine
48
Pt with fibromyalgia comes in with postural hypotension, urinary retention and dry mouth. side effect of?
TCAs
49
TCA side effects?
Convulsions, Coma, Cardiotoxicity
50
Pt given amitriptyline and has confusion and hallucinations. Try this instead
2ndary TCA like nortriptyline have fewer anticholinergic side effects than tertiary TCAs like amitriptyline
51
TCA that is less sedating and has lower seizure threshold?
Desipramine
52
PT with arrhythmia, and convulsions. Goes into coma. Treat arrythmia with?
Side effects of TCAs. Tx with HCO3.
53
MAO-Is?
Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline MAO Takes Pride In Shanghai
54
Selective MAO-B Inhibitor?
Selegiline
55
MAOIs vs SNRIs, vs TCAs,
MAOIs - block degradation of NE,5HT,DA SNRI - block reuptake of NE,5HT TCAs - block reuptake of NE, NE
56
tx for hypochondriasis?
MAO-Is
57
Tx for Atypical depression?
MAO-Is
58
If on this drug, cannot eat this food because it will cause this
MAO-I don't eat wine/cheese. Increased tyramine will cause hypertensive crisis
59
Contraindications of MAO-Is?
TCAs, St. John's wart, meperidine, dextromethorphan
60
Antidepressant used for smoking sensation affects these NTs?
Bupropion increases NE and DA by unknown ways
61
Drug causes seizures in bulimic and anorexic pts?
Bupropion
62
atypical Antidepressant Drug with no sexual side effects?
Bupropion
63
MoA of Antidepressant that is also used for anorexics to gain weight?
Mirtazapine. 1) a2 antag (increases NE and 5HT) 2) antag of 5HT2 and 5HT3
64
Drug used as an antidepressant and sleep aid?
Mirtazapine
65
MoA of Antidepressant that can cause sedation and orthostatic hypotension?
Maprotiline. blocks NE reuptake
66
Used primarily for insomnia but is an antidepressant at high doses?
Trazodone
67
Side effect of trazodone?
priapism (trazobone), postural hypotension
68
Pt gets dystonia from neuroleptic. Treat with?
Anticholinergic (benztropine)

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