Flashcards in Psych Pharm Deck (68):
Preferred drug: EtOH withdrawal?
Preferred drug: anxiety
SSRI, SNRIs, buspirone
Preferred drug: ADHD
Preferred drug: bipolar
lithium, valproate, carbamazepine
Preferred drug: bulemia
Preferred drug: depression
SSRI, SNRI, TCA, buspirone
Preferred drug: depression with insomnia
Preferred drug: OCD
Preferred drug: Panic disorder
SSRIs, venlafaxine, benzos
Preferred drug: PTSD
Preferred drug: social phobias?
Preferred drug: tourette's
Drugs that increase catecholamines at synaptic cleft, esp DA and NE. Use?
Methylphenidate, dextroamphetamine, methamphetamine. ADHD, narcolepsy, appetite control
Pt wants to control appetite. Can give?
MoA of antipsychotics?
Haloperidol and -azines. Block D2 receptors, increasing cAMP.
Side effects of high potency antipsychotics?
Trifluoperazine, Fluphenazine, Haloperidol (Try to Fly High). Extrapyramidal symptoms Dyskinesias etc)
Side effects of low potenncy antipsychotics?
Chlorpromazine, thioridazine. (Cheating theives are low). Anticholinergic, antihistamine, a1-block
Antiphychotic treat what type of schizophrenia symptoms?
Side effect in female schizophrenic treated with antipsychotic?
Galactorrhea (decreased DA -> more prolactin)
Pt comes in with a slowly developing rigidity, myoglobinema, and fever, encephalopathy. Cause? Treat with?
Neuroletic malignant syndrome. Dantrolene and D2 ags (bromocriptine)
Fever, encephalopathy, unstable vitals, elevated enzymes, rigidity of muscles
Pt with well controlled, long term phychosis comes in with stereotypic oral-facial movements. From what drug?
tardive dyskinesia from high potency antipsychotics.
Evolution of EPS side effects?
4 hr dystonia
4 day akathisia (restlessness)
4 wk bradykinesia
4 mo tardive dyskinesia
Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
(Its atypical for OLd CLOSets, to QUIETly RISPER from A to Z)
Corneal deposits, side effect of what antipsychotic? Retinal deposits?
Drugs that have various effects on 5HT2, DA, a-ad, and H1 recptors - used for?
Schizo (both + and - symptoms)
Bipolar, OCD, anxiety, depression, mania
Atypical that may cause weight gain?
Clozapine and olanzapine
Atypical that needs to be monitored weekly?
Clozapine - agranulocytosis.
Watch clozapine closely
Atypical that may prolong QT?
Psych drug used for SIADH
Side effects of Lithium?
Nephrogenic diabetes insipidus
Pregnant women takes lithium. risk of
Ebstein's anomaly (tricuspid problem( and malformation of great vessels
Problem with lithium
narrow therapeutic window
Li excreted by? (most is resorbed where?)
kidney; PCT with Na
Pt comes in with heart block and polyuria - what psych drug is she on?
MoA of drug for GAD that does not interact with alcohol
Buspirone. Stimulates 5HT1a.
Anxiously waiting for the BUS
Fluoxetine, paroxetine, sertraline, citalopram
Flashbacks paralyze senior citizens
Pt comes in complaining SSRI isn't working. Say?
wait 8 weeks
Pt comes in with rapid onset fever, confusion, myoclonus and heart problems. Drugs that caused it? MoA of drug that can Tx?
Serotonin syndrome (MAOIs, SSRIs, SNRIs), Tx with cyproheptadine, 5HT2 antag
depressed Pt had too many side effects on drug. Replaced with another drug that alleviated most effect but caused anorgasmia.
SSRI, fewer side effects than TCAs, but anorgasma
Venlafaxine and duloxetine
Used in panic disorders and GAD?
psych drug used for diabetic perpheral neuropathy?
SNRI with greater effect on NE?
Pt comes in with increased BP, nausea and sedation. Side effect of?
TCA - suffixes and exceptions?
-iptyline and -ipramine
except doxepin and amoxapine
TCA for bedwetting
TCA for OCD
Pt with fibromyalgia comes in with postural hypotension, urinary retention and dry mouth. side effect of?
TCA side effects?
Convulsions, Coma, Cardiotoxicity
Pt given amitriptyline and has confusion and hallucinations. Try this instead
2ndary TCA like nortriptyline have fewer anticholinergic side effects than tertiary TCAs like amitriptyline
TCA that is less sedating and has lower seizure threshold?
PT with arrhythmia, and convulsions. Goes into coma. Treat arrythmia with?
Side effects of TCAs. Tx with HCO3.
Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline
MAO Takes Pride In Shanghai
Selective MAO-B Inhibitor?
MAOIs vs SNRIs, vs TCAs,
MAOIs - block degradation of NE,5HT,DA
SNRI - block reuptake of NE,5HT
TCAs - block reuptake of NE, NE
tx for hypochondriasis?
Tx for Atypical depression?
If on this drug, cannot eat this food because it will cause this
MAO-I don't eat wine/cheese. Increased tyramine will cause hypertensive crisis
Contraindications of MAO-Is?
TCAs, St. John's wart, meperidine, dextromethorphan
Antidepressant used for smoking sensation affects these NTs?
Bupropion increases NE and DA by unknown ways
Drug causes seizures in bulimic and anorexic pts?
atypical Antidepressant Drug with no sexual side effects?
MoA of Antidepressant that is also used for anorexics to gain weight?
1) a2 antag (increases NE and 5HT)
2) antag of 5HT2 and 5HT3
Drug used as an antidepressant and sleep aid?
MoA of Antidepressant that can cause sedation and orthostatic hypotension?
Maprotiline. blocks NE reuptake
Used primarily for insomnia but is an antidepressant at high doses?
Side effect of trazodone?
priapism (trazobone), postural hypotension