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Flashcards in Psych Pharm Deck (68):
1

Preferred drug: EtOH withdrawal?

Benzos

2

Preferred drug: anxiety

SSRI, SNRIs, buspirone

3

Preferred drug: ADHD

Methylphenidate, amphetamine

4

Preferred drug: bipolar

lithium, valproate, carbamazepine

5

Preferred drug: bulemia

SSRI

6

Preferred drug: depression

SSRI, SNRI, TCA, buspirone

7

Preferred drug: depression with insomnia

mirtazapine

8

Preferred drug: OCD

SSRI, clomipramine

9

Preferred drug: Panic disorder

SSRIs, venlafaxine, benzos

10

Preferred drug: PTSD

SSRIs

11

Preferred drug: social phobias?

SSRIs

12

Preferred drug: tourette's

haloperidol, risperidone

13

Drugs that increase catecholamines at synaptic cleft, esp DA and NE. Use?

Methylphenidate, dextroamphetamine, methamphetamine. ADHD, narcolepsy, appetite control

14

Pt wants to control appetite. Can give?

Methylphenidate, -amphetamines

15

MoA of antipsychotics?

Haloperidol and -azines. Block D2 receptors, increasing cAMP.

16

Side effects of high potency antipsychotics?

Trifluoperazine, Fluphenazine, Haloperidol (Try to Fly High). Extrapyramidal symptoms Dyskinesias etc)

17

Side effects of low potenncy antipsychotics?

Chlorpromazine, thioridazine. (Cheating theives are low). Anticholinergic, antihistamine, a1-block

18

Antiphychotic treat what type of schizophrenia symptoms?

postive

19

Side effect in female schizophrenic treated with antipsychotic?

Galactorrhea (decreased DA -> more prolactin)

20

Pt comes in with a slowly developing rigidity, myoglobinema, and fever, encephalopathy. Cause? Treat with?

Neuroletic malignant syndrome. Dantrolene and D2 ags (bromocriptine)

NMS: FEVER
Fever, encephalopathy, unstable vitals, elevated enzymes, rigidity of muscles

21

Pt with well controlled, long term phychosis comes in with stereotypic oral-facial movements. From what drug?

tardive dyskinesia from high potency antipsychotics.

22

Evolution of EPS side effects?

4 hr dystonia
4 day akathisia (restlessness)
4 wk bradykinesia
4 mo tardive dyskinesia

23

Atypical antipsychotics

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
(Its atypical for OLd CLOSets, to QUIETly RISPER from A to Z)

24

Corneal deposits, side effect of what antipsychotic? Retinal deposits?

Chloropromazine, Thioridazine

25

Drugs that have various effects on 5HT2, DA, a-ad, and H1 recptors - used for?

Schizo (both + and - symptoms)
Bipolar, OCD, anxiety, depression, mania

26

Atypical that may cause weight gain?

Clozapine and olanzapine

27

Atypical that needs to be monitored weekly?

Clozapine - agranulocytosis.

Watch clozapine closely

28

Atypical that may prolong QT?

Ziprasidone

29

Psych drug used for SIADH

Lithium

30

Side effects of Lithium?

LMNOP
Lithium
Movement (tremor)
Nephrogenic diabetes insipidus
HypOthyroidism
Pregnancy Problems

31

Pregnant women takes lithium. risk of

Ebstein's anomaly (tricuspid problem( and malformation of great vessels

32

Problem with lithium

narrow therapeutic window

33

Li excreted by? (most is resorbed where?)

kidney; PCT with Na

34

Pt comes in with heart block and polyuria - what psych drug is she on?

Li

35

MoA of drug for GAD that does not interact with alcohol

Buspirone. Stimulates 5HT1a.

Anxiously waiting for the BUS

36

SSRIs?

Fluoxetine, paroxetine, sertraline, citalopram

Flashbacks paralyze senior citizens

37

Pt comes in complaining SSRI isn't working. Say?

wait 8 weeks

38

Pt comes in with rapid onset fever, confusion, myoclonus and heart problems. Drugs that caused it? MoA of drug that can Tx?

Serotonin syndrome (MAOIs, SSRIs, SNRIs), Tx with cyproheptadine, 5HT2 antag

39

depressed Pt had too many side effects on drug. Replaced with another drug that alleviated most effect but caused anorgasmia.

SSRI, fewer side effects than TCAs, but anorgasma

40

SNRIs

Venlafaxine and duloxetine

41

Used in panic disorders and GAD?

Venlafaxine

42

psych drug used for diabetic perpheral neuropathy?

Duloxetine

43

SNRI with greater effect on NE?

Duloxetine

44

Pt comes in with increased BP, nausea and sedation. Side effect of?

SNRIs

45

TCA - suffixes and exceptions?

-iptyline and -ipramine
except doxepin and amoxapine

46

TCA for bedwetting

imipramine

47

TCA for OCD

clomipramine

48

Pt with fibromyalgia comes in with postural hypotension, urinary retention and dry mouth. side effect of?

TCAs

49

TCA side effects?

Convulsions, Coma, Cardiotoxicity

50

Pt given amitriptyline and has confusion and hallucinations. Try this instead

2ndary TCA like nortriptyline have fewer anticholinergic side effects than tertiary TCAs like amitriptyline

51

TCA that is less sedating and has lower seizure threshold?

Desipramine

52

PT with arrhythmia, and convulsions. Goes into coma. Treat arrythmia with?

Side effects of TCAs. Tx with HCO3.

53

MAO-Is?

Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline

MAO Takes Pride In Shanghai

54

Selective MAO-B Inhibitor?

Selegiline

55

MAOIs vs SNRIs, vs TCAs,

MAOIs - block degradation of NE,5HT,DA
SNRI - block reuptake of NE,5HT
TCAs - block reuptake of NE, NE

56

tx for hypochondriasis?

MAO-Is

57

Tx for Atypical depression?

MAO-Is

58

If on this drug, cannot eat this food because it will cause this

MAO-I don't eat wine/cheese. Increased tyramine will cause hypertensive crisis

59

Contraindications of MAO-Is?

TCAs, St. John's wart, meperidine, dextromethorphan

60

Antidepressant used for smoking sensation affects these NTs?

Bupropion increases NE and DA by unknown ways

61

Drug causes seizures in bulimic and anorexic pts?

Bupropion

62

atypical Antidepressant Drug with no sexual side effects?

Bupropion

63

MoA of Antidepressant that is also used for anorexics to gain weight?

Mirtazapine.
1) a2 antag (increases NE and 5HT)
2) antag of 5HT2 and 5HT3

64

Drug used as an antidepressant and sleep aid?

Mirtazapine

65

MoA of Antidepressant that can cause sedation and orthostatic hypotension?

Maprotiline. blocks NE reuptake

66

Used primarily for insomnia but is an antidepressant at high doses?

Trazodone

67

Side effect of trazodone?

priapism (trazobone), postural hypotension

68

Pt gets dystonia from neuroleptic. Treat with?

Anticholinergic (benztropine)