Flashcards in Renal Pharm Deck (25):
Drugs that act in the PCT?
Mannitol and Acetazolamide
Pt with increased ICP and IOP? Diuretic that can be given?
pulmonary edema and dehydration are Toxicities of what diuretic?
Pt with CHF. Do not give this diuretic?
Pt with anuria. Contraindicated diuretic?
Drug that causes self-limited NaHCO3 diuresis. Uses? cause what type of acid-base disturbance?
Acetazolamide. Used for Glaucoma, metabolic alkylosis, altitude sickness, pseudotumor cerebri. Hyperchloremic Acidosis
Pt treated for altitude sickness. Comes in with NH3 toxicity. Drug?
Pt treated for pseudotumor cerebri. Comes in with paresthesias. Other toxicities
Acetazolamide. HyperCl Metabolic acidosis ammonia toxicity, sulfa allergy
Drugs that work in TAL?
Loop diuretics and Ethacrynic acid
Drug that abolishes hypertonicity of medulla, preventing concentration of urine. Can cause excretion of what electrolytes?
Loop diuretics (furosemide). Excretion of Ca and K
Pt on that drug that stimulates PGE release to vasodilate AA. Toxicities?
Furosemide - OH DANG
Pt on this drug for diuresis in loop of henle has sulfa allergy. Derived from? Never use it to treat?
Ethacrynic acid. Phenoxyacetic acid. Can cause hyperuricemia, never use to treat gout
Drug that should never be given with pt with gout?
Ethacrynic acid (can cause hyperuricemia)
Diuretic that may cause hyperCa, may also cause?
HCT. Hyper-glycemia, -lipidemia, -uricemia, -calcemia
This diuretic can be used for nephrogeneic diabetes insipidus?
This diuretic can be paradoxically used for idiopathic hyperCa?
Diuretic for CHF?
HCT or K-sparing
K sparing diuretics?
The K STAys
Spirolactone, Amiloride, Triamterene and eplerenone
Diuretics that can cause gynecomastia, also block?
Spirolactone and eplerenone. Block ALDO
Diuretics that may cause acidosis?
Carbonic Anhydrase inhibitors (decrease HCO3)
K-sparing (decreases K/H secretion)
MoAs Diuretics that may cause Alkalemia?
Loop diuretics and thiazides
1) increase HCO3 while volume contracting
2) K loss leads to H entering cells
3) In low K states, H is excreted in exchange for Na
Ca increased with this diuretic? Decreased with this?
Diuretic that can prevent unfavorable heart remodeling as a result of chronic hypertension?
ACE-Is - side effects?
Creatinine increase (down GFR)