Flashcards in Quiz 3: Phosphorus Deck (8)
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1
Locations of Phosphorus in the body
- 80% of phosphate found in bone
- 20% in soft tissue
- < 1 % in serum/plasma
2
Causes of interference in Phosphorus measurement
EDTA, Citrate, oxalate anticoagulants interfere with most assay methods.
Hemolysis increases PO4 since it is predominately intracellular
3
Phosphorus Reference Values
Serum/Plasma: 2.7 - 4.5 mg/dL
Urine: 0.4 -1.3 g/d (400-1300 mg/d)
4
Measurement of Inorganic Phosphorus
Only form measured by Lab
Phosphate ion + ammonium molybdate = phosphomolybdate complex
When a stannous Cl reducer is added = molybdate blue complex forms, which can be read at 600 - 700 nm.
5
Hyperphosphatemia
Chronic Renal Failure
Hypoparathyroidism
Excess Vitamin D
6
Hypophosphatemia
–not common
Hyperparathyroidism
Impaired Renal Absorption
7
Phosphorus
Has an inverse relationship with Ca
8
