Quiz 3: Phosphorus Flashcards Preview

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Flashcards in Quiz 3: Phosphorus Deck (8)
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1

Locations of Phosphorus in the body

- 80% of phosphate found in bone
- 20% in soft tissue
- < 1 % in serum/plasma

2

Causes of interference in Phosphorus measurement

EDTA, Citrate, oxalate anticoagulants interfere with most assay methods.
Hemolysis increases PO4 since it is predominately intracellular

3

Phosphorus Reference Values

Serum/Plasma: 2.7 - 4.5 mg/dL
Urine: 0.4 -1.3 g/d (400-1300 mg/d)

4

Measurement of Inorganic Phosphorus

Only form measured by Lab
Phosphate ion + ammonium molybdate = phosphomolybdate complex
When a stannous Cl reducer is added = molybdate blue complex forms, which can be read at 600 - 700 nm.

5

Hyperphosphatemia

Chronic Renal Failure
Hypoparathyroidism
Excess Vitamin D

6

Hypophosphatemia

–not common
Hyperparathyroidism
Impaired Renal Absorption

7

Phosphorus

Has an inverse relationship with Ca

8

Phosphorus Regulation

Absorption and excretion in Kidneys, caused by PTH (excretion), and VitD (intestinal and renal reabsorption)