Flashcards in Repro & Endocrine Deck (74)
Name a common mineralocorticoid drug
What percentage of the body's Ca2+ is found in bone?
What is it found as?
What is PTH secretion controlled by?
What are the effects of PTH?
Increases Ca2+ by affecting transport mechanisms in bone, kidney, and indirectly (via Vit D) the intestine
Increased absorption from GI tract
Increased osteoclastic activity so that Ca2+ is released from bone into blood
Increases renal excretion of phosphate
What does vitamin D3 do?
Enhances Ca2+ uptake from small intestine
Increases intestinal absorption of phosphate and decreases renal excretion
What does calcitonin do?
Where is it released from?
Decreases Ca2+, largely by affecting transport mechanisms in bone (less active bone remodelling by osteoclasts)
Comes from parafollicular cells of thyroid gland
Why might you not administer calcium IV?
Can cause cardiac arrhythmias and arrest
What is calcitriol?
Active vitamin D3
Vasopressin and desmopressin are examples of what?
What are they used to diagnose/treat?
Used to diagnose and treat diabetes insipidus
What is somatotropin?
A growth hormone stimulant
What does cabergoline do?
What is it used for?
Induces oestrus and abortion in bitches
Treats false pregnancy
What are the 6 hormones produced by the anterior pituitary gland?
FSH, LH, ACTH, TSH (thyroid stimulating hormone), GH and prolactin
What are the 2 types of receptor for sex-steroid hormones?
Nuclear receptors (slow)
Membrane receptors (fast)