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Year 2 Semester 2 > Repro & Endocrine > Flashcards

Flashcards in Repro & Endocrine Deck (74)
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61

Name a common mineralocorticoid drug

Fludrocortisone

62

What percentage of the body's Ca2+ is found in bone?
What is it found as?

99%
Hydroxyapatite

63

What is PTH secretion controlled by?

Serum-ionised calcium

64

What are the effects of PTH?

Increases Ca2+ by affecting transport mechanisms in bone, kidney, and indirectly (via Vit D) the intestine
Increased absorption from GI tract
Increased osteoclastic activity so that Ca2+ is released from bone into blood
Increases renal excretion of phosphate

65

What does vitamin D3 do?

Enhances Ca2+ uptake from small intestine
Increases intestinal absorption of phosphate and decreases renal excretion

66

What does calcitonin do?
Where is it released from?

Decreases Ca2+, largely by affecting transport mechanisms in bone (less active bone remodelling by osteoclasts)
Comes from parafollicular cells of thyroid gland

67

Why might you not administer calcium IV?

Can cause cardiac arrhythmias and arrest

68

What is calcitriol?

Active vitamin D3

69

Vasopressin and desmopressin are examples of what?
What are they used to diagnose/treat?

Anti-diuretics
Used to diagnose and treat diabetes insipidus

70

What is somatotropin?

A growth hormone stimulant

71

What does cabergoline do?
What is it used for?

Stops lactation
Induces oestrus and abortion in bitches
Treats false pregnancy

72

What are the 6 hormones produced by the anterior pituitary gland?

FSH, LH, ACTH, TSH (thyroid stimulating hormone), GH and prolactin

73

What are the 2 types of receptor for sex-steroid hormones?

Nuclear receptors (slow)
Membrane receptors (fast)

74

Name the commonly-used exogenous oestrogen

Oestradiol