respiration 1 Flashcards

(52 cards)

1
Q

Function of respiratory system

A
O2
Eleimate Co2
Regulat Ph
Speech
Microbial defecence
Activate/inactivate chem messengers in blood
defend against blood clots
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2
Q

what is the most critical function of the respiratory system

A

deliver O2

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3
Q

what is the problem with lots of CO2 in the blood

A

acidic waste product

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4
Q

how does the respiratory system provide microbial defense

A

Epithelial secretion
Lymphoid tissue in tract
Coughing and sneezing reflexes

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5
Q

how does the respiratory system defend against blood clots

A

Small blood clots get trapped in narrow vessels in lungs and are dissolved

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6
Q

what are the series of tubes needed to exchange air betwen lungs and environment

A

Airways

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7
Q

what makes up the upper airway

A

Structures outside the thoracic cavity

  • mouth/nose
  • pharynx
  • larynx
  • top of trachea
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8
Q

what makes up the conducting zone

A

thoracic cavity, but no gas exchange occurs

  • trachea
  • primary bronchi
  • sec bronchi
  • tertiary bronchioles
  • bronchioles
  • terminal bronchioles
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9
Q

what makes up the trachea and bronchi

A

cartilaginous rings

mucous glands

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10
Q

what makes up the bronchioles

A

Lose cartilage, glands, smooth muscle

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11
Q

what makes up the respiratory zone

A

Structures where gas exchange occurs

  • respiratory bronchioles
  • alveolar ducts
  • alveolar sacs
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12
Q

functions of the conducting zone

A

Branching
Air is warmed and moistening
protection against microbes

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13
Q

what is the amount of branching in the conducting zone

A

1->8 mill tubes

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14
Q

what is responsibly for warming and moistening the air in the conducting zone

A

Heat and water vapor are exchanged with blood in airway walls

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15
Q

what does the trachea do to protect against microbes

A

Goblet cells secrete mucus that traps airborne particles and pathogens

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16
Q

what does the eipithelial layer have to protect aginst pathogens

A

Epithelial cells move mucs up to pharynx to be swallowed or expelled

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17
Q

what does the mutation in cystic fibrosis change

A

Cl- channel changes the amount of Na and Cl secreted across the epithelium into mucus
= less water in mucus, so mucus dry and thick

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18
Q

how does cystic fibrosis lead to disease

A

infectious agents trapped not expelled and airways are obstructed

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19
Q

what regulates the airflow in the lungs

A

Bronchiolar Smooth muscle

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20
Q

why are the alveoli well suited for optimizing gas exchange

A

High surface area
high vascularized
Respiratory surface very thin
low rate of bloodflow provides time for exchnage

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21
Q

what provides microbial defense in the respiratory zone

A

Pulmonary macrophages

22
Q

what are the cells of the alveoli

A

Type I
Type II
macrophages

23
Q

what is the roll of type I alveoli cels

A

Epithelium for gas exchange surface

24
Q

what is the roll of type II alveoli cells

A

Secrete surfactant

25
what is the diameter of the alveolar sacs
.5 micrometers in diameter
26
what is the distance between alveolus and capillary
.2 micrometers
27
polarity of respiratory gases diffuse
small and non-polar
28
solubility of O2 and CO2
CO2=77 mmol/L | O2=2.2mmol/L
29
what must a gas cross to get into blood from the lungs
``` across apical membrane of type I cell Through cytoplasm across basal membrane of Type I cell Across basal almina and underlying connective tissue acoss basal membrande of endo cell through cytoplasm across apical membrane of endo cell plasma ```
30
what must a gas cross to get from blood to the tissue
reverse of how air goes from lungs to blood
31
what surrounds earch lung
a pleural sac made of two layers
32
what adheres to the underside of the thoracic wall and the top of the diaphram
parietal pleua
33
what covers the outer surface of the lung
Visceral pleura
34
what is the pleural sacq
the space between the parietal and visceral pleura
35
how thick is the intrapleural fluid
10-20 micrometers thick
36
what is the physics of ventilation of the lungs
relies on pressure difference
37
what is th flow equation
Flow= difference in Pressure from atm to lung/Resistance
38
what are the relative pressure for inspiration
pressure of alveolus is less than atmosphere
39
what is the relative pressure for expiration
pressure of the alveolus is greater than the atmosphere
40
what causes alveolar pressure to change
response to chnaging volume of the lungs (BOYLE'S law)
41
what are the important pressures used in ventilation
alveolar pressure intrapleural pressure transpulmonary pressure
42
what is intrapleural pressure
the pressure in the fluid of the intrapleural space
43
what is transpulmonary pressure
the difference in pressure between the intrapleural space and the alvelar pressure
44
what muscles are used in inspiration
Contraction of diaphram | external intercostal contraction
45
what muscles are used in expiration
relaxation of diaphram external intercostals relax internal intercostal contract
46
what is the alveolar pressure, atmospheric and intrapleural pressure at rest
alvolar and atm equal | intrapleural below atm
47
why is intrapleural pressue always subatmospheric
Lungs recoil inward | chest wall recoils outward
48
how does intrapleural pressure, transpulmonary and alveolar and atmospheric pressure change during inspiration
Intrapleural becomes more negative transpleural increrases air flows in until alveolar pressure equal atmospheric pressure
49
how does intrapleural pressure, transpulmonary and alveolar and atmospheric pressure change during expiration
intrapleural becomes less negative transpleural decreases air flows out until alveolar and atmospheric pressure are equal
50
what causes a pneumothorax occur
lung or pleural sac is punctured
51
does a pneumothroax happen to one or two lungs
just one lung
52
what causes the pneumothorax to colapse a lung
different pressures no longer exist so lung colapses and chest wall expands