Flashcards in Respiratory Drugs Deck (31):
What 2 drugs can be used more effectively to TX Aspergillosis locally in dogs? (TQ)
What are the 3 systemic imidazoles?
What is the major S.E. of imidazoles?
Which drugs can be used to locally TX Guttural Pouch Mycosis in equines?
Anti-tussives should only be used when?
Only w/ severe NON-PRODUCTIVE cough
What are the opioids used as anti-tussives?
Which opioids have limited S.E.?
Anti-tussive w/ low potency & weak CNS suppression. Used in horses & cattle (TQ)
Which drug has beneficial effects in horses (BAL procedure)?
How does Acetylcystiene modify airway mucus?
Breaks up by disrupting disulphydryl bonds
A _____ of respiratory lumen will lead to an increase of resistance. (TQ)
(diameter/2 = resistance*16)
What 3 classes of drugs can you use to modify airway resistance? (TQ)
ACH M3 ANTagonists
Beta 2 agonists
What 4 drugs can be used to stimulate respiration?
What 3 drugs can be used to suppress the cough reflex?
What 4 drugs can be used to modify airway mucus consistency?
What 2 drugs are stimulating expectorants?
What 3 drugs are reflex expectorants?
What is a non-specific anticholingeric drug used to modify airway resistance?
What anticholingeric can be used to evaluate responsiveness in COPD?
Which 3 anticholingeric drugs can you administer per inhalation? (stays local & don't need [high])
What are the 3 effects of beta 2 agonists binding to the G-protein coupled receptor? (know)
1. activates adenylate cyclase
2. incr. cAMP production
3. activates of PKA
What are the 3 Beta-2 agonists used to modify airway resistance? (know)
Which alpha1- adrenergic decongestant causes reflex vasoDILATION?
What are the phosphodiesterase inhibitors used to modify airway resistance?
Theophylline (most used clinically)
MOA of Theophylline.
Believed to inhibit PDE--> incr. cAMP--> incr. mucociliary clearance
Never give NSAIDs under what conditions?
Acute severe bronchoconstriction --> DEATH
Asthma (aspirin induced asthma)
What are the 2 mast cell stabilizers? (TQ)
What are the 4 ways glucocorticoids help reduce inflammation & inhibit mediator release?
reduce mucosal edema
suppress immune rxns
sensitize smooth mm. to Beta adrenergic drugs
Don't combine expectorants w/ what?
Alpha adrenergics (decrease secretions)
What are the 3 classes of drugs commonly used as bronchoDILATORS? (TQ)