Rest of NJCTL and Class Notes for Membranes & Proteins Section Flashcards
(cell signaling) cellular signaling is a part of a complex system of communication that governs basic … and coordinates …
cellular activities; cell actions
(cell signaling) the ability of cells to perceive and correctly respond to their microenvironment is the basis of …, …, and ….
development; tissue repair; immunity
(cell signaling) cells within multicellular organisms must communicate with one another to coordinate all aspects of life. single-celled organisms also communicate with one another to perform certain … tasks
symbiotic
(cell signaling) correct and appropriate signaling pathways are generally under …. and show shared evolution among organisms with ….
strong selective pressure; shared pathways
(signal transduction) transcription factors are … regulating the initiation of ….. They cause a cell to respond to a … in the … in a very specific way
cofactors; gene transcription; signal; environment
(signal transduction) this signal is anything that the cell has the ability to respond to. It could be …, a …, a …, …, etc
light; chemical; hormone; heat;
(signal transduction) a signal transduction pathway proceeds with reception of a …, transduction of that signal through the cell to the …, and finally results in …. of a ….
signal; DNA; expression; transcription factor
(signal transduction) the pathway starts when a new … (aka …) reaches a cell
signal; ligand
(signal transduction) external signal activates membrane-bound protein known as a …. These are like … in that they will bind with only 1 kind of substrate (signal)
receptor; enzymes
(signal transduction) the activated receptor triggers a cascade reaction, a …
metabolic pathway
(signal transduction) the metabolic pathway produces a specific …. in response to the signal. The product initiates … of a …
transcription factor; transcription; response gene
(signal transduction) transcription factors initiate the … of additional genes, which coordinate the cell’s …
transcription; response to stimuli
(regulation) when a receptor receives an external signal from another cell, the response can either be to … or … the … of a specific … within the ell
increase; decrease; concentration; molecule
(regulation) increasing the concentration is called … and decreasing production of that molecule isi called …
upregulation; downregulation
(regulation) example of up/downregulation: if no glucose is present but lactose is , bacteria would … glucose receptors and … lactose receptors
downregulate; upregulate
(regulation) during upregulation, the number of … on the surface of target cells …, making the cells more sensitive to a hormone or another agent
receptors; increase
(regulation) example of upregulation: there is an increase in uterine …. in the third trimester of pregnancy, promoting the contraction of the smooth muscle of the uterus
oxytocin receptors
(regulation) downregulation is a … in the number of … on the surface of target cells, making the cells less sensitive to a hormone or another agent. some receptors can be rapidly downregulated.
decrease; receptors
(regulation) example of downregulation: in type II diabetes –> characterized by elevated levels of insulin in the bloodstream but a loss of …. this downregulation can sometimes be reversed through exercise, and occasionally, a change in diet can also resolve the issue
insulin receptors
(single-celled signaling) in single-celled organisms, signal transduction pathways influence how the cells respond to its environment. many single-celled organisms live in … with other organisms, responding to signals released by adjacent cells
symbiotic relationships
(single-celled signaling) certain bacteria use … to communicate to other nearby cells and regulate specific …. in response to …. this is known as …
chemical messengers; reproductive pathways; population density; quorum sensing
(single-celled signaling) pseudomonas aeruginosa use quorum sensing to coordinate cell … they grow within a host without harming it until they reach a certain … once that is reached, they release a signal to aggressively … in order to overcome the host’s …. the bacteria create a … wherein they form a layer that completely covers the host’s … and then reproduce at an exponential rate. research has shown that garlic inhibits the formation of these layers by blocking the quorum sensing pathway. This is called ….
aggregation; concentration; replicate; immune system; biofilm; tissue; quorum inhibition
(multicellular signaling) multicellular organisms have physical pathways between adjacent cells to aid in … and ….
communication; transfer of substances
(multicellular signaling) in animal cells these cell junctions are:
tight junctions: can bind cells together into …
adhering junctions: fasten cells together into …. They are somewhat …
communication (gap) junctions: allow substances to …. from cell to cell. they are totally …. they are the equivalent of … in plants
leakproof sheets; strong sheets; leakproof; flow; leaky; plasmodesmata