Sodium Citrate Flashcards Preview

Drug Cards > Sodium Citrate > Flashcards

Flashcards in Sodium Citrate Deck (12):
1

What is the trade name of Sodium Citrate?

Bicitra

2

What is the formal drug classification of Sodium Citrate?

nonparticulate antacid

3

What are the clinical uses for Sodium Citrate?

-systemic alkalizer and nonparticulate neutralizing buffer given before surgery to increase the pH of gastric fluid
-also used to maintain systemic urine alkalinity and to improve the chronic metabolic acidosis found in the syndrome of renal tubular acidosis or chronic renal insufficiency

4

What is the MOA of Sodium Citrate?

-Sodium citrate has a pH of 8.4 and works through direct neutralization of gastric pH
-also metabolized to sodium bicarbonate in the body, raising systemic as well as gastric pH
-this increased gastric pH is presumed to decrease the severity of aspiration pneumonitis should the high risk non-fasted patient aspirate gastric fluid

5

What is the onset of action for sodium citrate?

effective within 15-20 minutes

6

What is the metabolism of sodium citrate?

almost completely oxidized

7

How is sodium citrate eliminated?

less than 5% is excreted unchanged in the urine

8

What are the side effects of Sodium Citrate?

-unpleasant taste related to the pH and can cause N/V
-Will increase gastric Volume
-may decrease gastric emptying
-in an immobile patient, complete mixing with all gastric contents may not occur

9

what are the contraindications to sodium citrate?

NOT recommended for patients on a low sodium diet or with severe renal impairment

10

What are the drug interactions with Sodium Citrate?

Should not be given with Aluminum-containing Antacids

11

What is the dosage for Sodium Citrate?

30mL of 0.3M sodium citrate PO given 15-30 min before induction
For systemic alkalization, 10-30mL PO after meals and at bedtime

12

What may result in overdose of Sodium Citrate?

N/V/D, excessive mental activity or imagination, convulsions