Solid dosage forms AZ Flashcards Preview

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Flashcards in Solid dosage forms AZ Deck (11):
1

What is meant by friability?

The tendency for a tablet to chip, crumble or break following compression

2

What is meant by crushing force?

The force required to break the tablet along a given axis

3

What is meant by tensile strength?

Stress required to induce flow in the material i.e. resistance to breaking under tension

4

What are the units for crushing force?

Newtons or kiloponds

5

Why can't crushing force be compared across tablet sizes?

Because it is dependent of tablet size and shape

6

Is tensile strength dependent of tablet size and shape?

No, it is independent of them

7

What does tensile strength depend on?

Porosity of the tablet - a more porous tablet is more easily crushed

8

Do porous tablets have a high or low disintegration rate?

The more porous the tablet, the faster the disintegration rate

9

A higher punch pressure gives a less porous tablet. True or false?

True

10

What is the disintegration time specified by the pharmacopoeia for IR formulations?

less than 15 mins

11

What sort of light should tablet appearance be tested under?

White light