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Flashcards in Structure of Bone Deck (23):
1

What cell is bone derived from?

Mesenchymal cells

2

What type of bone forms the dense outer cortex?

Compact corticle bone

3

What type of bone forms the inner cavity of bones?

Trabecular/spongy bone meshwork

4

What lines the inside of a medullary cavity?

Endosteum

5

What lines the outside of the medullary cavity?

Periosteum

6

What is the name given to the ends of long bones?

Epiphysis (where bone growth occurs)

7

What is the name given to the middle of long bones?

Diaphysis

8

Describe woven bone?

Immature bone with an irregular pattern
Extracellular matrix is made up of collagen fibrils

9

describe lamellar bone?

Mature bone with haversian systems arranged in layers
In can exist as either compact or trabecular

10

Where is woven bone found in an adult?

Tooth socket
Cranial sutures

11

What is found on the outer layers of haversian bone?

Collagen and blood vessels

12

What forms the inner layer of haversian bone and what is found here?

Internally lined with endosteum containing osteoprogenitor cells and reticular fibres

13

What travels in the central canal of haversian systems?

Blood vessels

14

What are Volksman's canals?

Perindicular (to the central haversian canal) containing blood vessels

15

What connects muscle tendons to bone?

Sharpey's fibres

16

What structure traps immobile osteocytes?

Lacunae

17

What is the chemical formula of hydroxyapetite?

Ca10(PO4)6(OH)2

18

Name all of the organic compounds involved in bone mineralisation?

Osteoid collagen
Proteins x2
Proteoglycans

19

Name the two organic proteins and which one is secreted by osteoblasts?
What is their function?

Osteopontin
Osteocalcin (secreted by osteoblasts)
Bind osteoblasts to the bone matrix

20

What type of collagen fibrils make up osteoid collagen?

Type I

21

Name the inorganic compounds involved in bone mineralisation?

Hydroxyapetite

22

What does hydroxyapetite seeding and growth depend on?

Concentration of Calcium and Phosphate

23

Bone can only grow where crystal nuclei can form, what does normal tissue contain to prevent bone formation?

Pyrophosphates