systemic disease Flashcards

(52 cards)

1
Q

ct disese incude

A

systemic lupus erthemoass
systemic scleroiss
sjogrens
auto immune myositsi
mixed ct disase

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2
Q

systemic vascultis incdleu

A

giant cell arteri
garmaulosis with polyagniitis
- wegneer
micro scopic opolangits
eoinophcil granulmatoiss with polyangiitisi

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3
Q

drugs that mimmic systmie dise inace

A

cocaine, minocylcine, proppylthiocuracil

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4
Q

media cnodiotn taht mimic sytmeic disease include

A

cardiac myxoma
cholesterol emboli
scuvy

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5
Q

systemic lupus erthermatosu presents as which rah

A

a butterfly rash
spares noaslabia folds
malar

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6
Q

lupus mianly effects

A

females

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7
Q

cuase of luypus flaries ups i

A

uv light
drugs
invesions

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8
Q

lupsus is due to

A

immune repsone agais endogenou nucler antigens
causes tissue injyr
compelte activaiotn
immune compex formaiotn

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9
Q

signs of lupus in skin

A

vasuclit, puprua, urtica

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10
Q

signs of lupus chest

A

pericarids, endocarid, arotic vacle lesion

plurist, pulre effcuion

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11
Q

signs of lupus nervous sysetm

A

fits, hemiplagia, ataxia, peripal neruopay, cranila nerve lesions

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12
Q

signs of lupus joints

A

aspectic necois of hip
arhtitis in small jionts

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13
Q

signs of lupus blood

A

anemai, leukopenai, thrymopcytopiean

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14
Q

signs of luus joins

A

asecpic neocis,
arhtisisi in small jionts

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15
Q

classifactio of lupus is abed of

A

4 out of 11 pionts

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16
Q

antiobs of lupus is

A

ana - but not spefici due to being in 10% of general pop

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17
Q

helpusl antiboids in lupus

A

anti ds dna - 605 - nepthitsi link
antismith - 10% highly spefici
anti ro - risk of feotal congeial heart block
antiphsopic - anticardiolip, anti coagusltn, - risk of miscarge and vessel thrombosis

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18
Q

types of systemec is

A

diffece cutaboues
limited cuterouss

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19
Q

lcoalsed scleroma presnet as

A

lina morpah - small lines of effected skin
plaque morepha - large pathces of effected skin

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20
Q

systemic scloer risk facos are

A

solevents, silcia, viarla incfiton

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21
Q

pathogenis of systemic sclosis is

A

vasuclar damge, immune system acivion, fibrosis

22
Q

systmiec cosis miany effects

A

female 30 - 50

23
Q

limiated cutous systmeic sclosis mialy cuases - pnemoaic

A

C – Calcinosis
R – Raynaud’s phenomenon
E – oEsophageal dysmotility
S – Sclerodactyly
T – Telangiectasia

and pulmary hyertenoinan dn gi

24
Q

diffus cutorse systmeic sclosis maily effects

A

interal organs
Cardiovascular problems (e.g., hypertension and coronary artery disease)
Lung problems (e.g., pulmonary hypertension and pulmonary fibrosis)
Kidney problems (e.g., scleroderma renal crisis)

small bowel overgrowth

25
antibodis of limated systemic scossi is
anti centomeer,
26
antiboids of diffuse sytmic sclerois si
anti scl170
27
sjorens syndoem is
a autime that efecs slaivary glnd and partod gland elarfement
28
antiboids of sjorens
anti ro and ant la
29
systemic upaent with sjogrens is
fatiuq,e feve,r malriga, arthalis, dry skin
30
onset of sjogenr is
40 - 50 , fmale 9;1
31
complicats of sjorgen is
lympnoa neuropathy, cuterous vasucirs, interistla lung disase, renal tubualr acidosis
32
myosisi is
mucls withakes due to degat with raised ck levesls
33
diganso of myoiss is
emg, mri, muclse biopay
34
antiboids with myloiss is
anti jo1 antibois
35
cutoantou effects of myosis is
gottrons papules heliotrope rahs
36
gottrons papuules are
inflaiton over joints in hand
37
heliotoape rahs is
a macular rahs over face that effects nasolabial area
38
large vesle vacuar incudes
takayasu and giant cell arthiers
39
medium vesl arteir inlude
kawaskai idsase and polyarteritis nodosa
40
small vessle artheri innce
anca asscoeated vascultis immune complex small vels vauslis
41
immune compex small vesl vauslar are
anti gbn iga vualsis cryoglobulinemeic vaulis hypocompletmetn curtriacialia vasulais
42
anaca asosicaed vsusi incude
microspic polyangitis granumlomatis with polyangiisi eiosophillic gnaulomatois with polyangutiis
43
need for a gian of gianct celar aits is
over 50 new heaahca tempa larteyr nteon abonal tempal biopay esr above 50
44
treamt of giant cell artier is is
prenisolone - 40 mg per day
45
giance cell cuase what probel with teh aorta
thickening anyerisms
46
gicant cell arhti long erm comaption
strokes irrevarl vison loss
47
takyalsisu arther efects
the aortic arch
48
talkayros maince is present in
woemn
49
symots of takaysus aritsi is
puslesnesl artiela insufiice, particly rin limbs increased risk of heart attk or stroke
50
granumlomatisi with polyahtisis presea as (wegnernese)
necorosis granulaois inflation hearling loss invoes upper and lower respitar tract sintusi hameotis neocirs glomeritsi
51
antiboeis of wegners / granulatoi with polyangiti
canca , anti pr3
52