Translation Flashcards
(19 cards)
Three nucleotides code for an
Amino acid
True or false: some amino acids have more than one codon
True
Where does protein translation occur
Ribosome
How does mRNA exit the nucleus
Nuclear pore
Stop codon in the wrong place
Nonsense mediated mRNA decayQ
Quality check = recognition of _______ and __________
5’ cap, poly A tail
The three mRNA binding sites in ribosomes
A, P, E
Site of ribosome biosynthesis
Nucleolus
Where are the 2 locations for ribosomes
- Free ribosomes in cytoplasm
- Rough ER
Couples amino acids to correct tRNA
Specific aminoacyl tRNA synthetase
What is the special initiator tRNA that starts translation
Methionine
Bond formed between amino acids
Peptide bond
What end of growing polypeptide chain are amino acids added to
C-terminal
UAG, UAA and UGA are
Stop codons
Newly synthesised amino acid chain released with help of
release factor
Bind to 5’-region of mRNA and prevent initiation of translation
Translational repressors
Megaloblastic anaemia is characterised by
Enlarged RBCs
What disease is caused by deficiencies in folic acid or vitamin B12
Megaloblastic anaemia