Translation Flashcards

(19 cards)

1
Q

Three nucleotides code for an

A

Amino acid

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2
Q

True or false: some amino acids have more than one codon

A

True

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3
Q

Where does protein translation occur

A

Ribosome

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4
Q

How does mRNA exit the nucleus

A

Nuclear pore

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5
Q

Stop codon in the wrong place

A

Nonsense mediated mRNA decayQ

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6
Q

Quality check = recognition of _______ and __________

A

5’ cap, poly A tail

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7
Q

The three mRNA binding sites in ribosomes

A

A, P, E

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8
Q

Site of ribosome biosynthesis

A

Nucleolus

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9
Q

Where are the 2 locations for ribosomes

A
  • Free ribosomes in cytoplasm
  • Rough ER
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10
Q
A
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11
Q

Couples amino acids to correct tRNA

A

Specific aminoacyl tRNA synthetase

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12
Q

What is the special initiator tRNA that starts translation

A

Methionine

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13
Q

Bond formed between amino acids

A

Peptide bond

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14
Q

What end of growing polypeptide chain are amino acids added to

A

C-terminal

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15
Q

UAG, UAA and UGA are

A

Stop codons

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16
Q

Newly synthesised amino acid chain released with help of

A

release factor

17
Q

Bind to 5’-region of mRNA and prevent initiation of translation

A

Translational repressors

18
Q

Megaloblastic anaemia is characterised by

A

Enlarged RBCs

19
Q

What disease is caused by deficiencies in folic acid or vitamin B12

A

Megaloblastic anaemia