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Flashcards in Vasculitides Deck (39)
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31

Microscopic polyangiitis bx?

- Necrotizing vasculitis in lungs, kidneys, skin
- Pauci-immune GN
- Palpable purpura
- NO GRANULOMAS

32

Microscopic polyangiitis marker?

p-ANCA (MPO-ANCA) - anti-myeloperoxidase

33

Microscopic polyangiitis rx?

Cyclophosphamide, corticosteroids

34

Churg-Strauss (eosinophilic granulomatosis with polyangiitis) presentation?

Asthma, sinusitis, skin nodules/purpura, peripheral neuropathy (wrist/foot drop)

35

Churg-Strauss (eosinophilic granulomatosis with polyangiitis) bx?

Granulomatous, necrotizing vasculitis with eosinophilia

36

Churg-Strauss (eosinophilic granulomatosis with polyangiitis) marker?

p-ANCA, increased IgE

37

Henoch-Schonlein purpura presentation?

KIDS, follows URI
- Skin: palpable purpura on buttocks/legs
- Arthralgias
- GI: abdominal pain and bleeding

38

Henoch-Schonlein purpura pathogenesis?

IgA immune complex deposition
Type III HSN

39

What renal thingamajig is Henoch-Schonlein purpura associated with?

IgA Nephropathy (Berger DZ)