Viral infections of skin and soft tissue I Flashcards Preview

Year 1 Microbiology > Viral infections of skin and soft tissue I > Flashcards

Flashcards in Viral infections of skin and soft tissue I Deck (23):
1

In which skin layer are new HPV virions forming?

Suprabasal

2

HPV belongs to what family?

Papovaviridae

3

Is HPV enveloped or non-enveloped?

Non-enveloped

4

What is the HPV genome?

dsDNA

5

What is the diagnosis for HPV warts?

Hyperkeratosis and koilocytes

6

What are koilocytes?

Cells with an aberrant, large nucleus surrounded by an unstained halo

7

What condition is characterized by large eosinophilic cytoplasmic inclusions?

Molluscum contagiosum (molluscum bodies)

8

Molluscum contagiosum belongs to what family?

Poxviridae

9

What is the molluscum contagiosum genome?

Large dsDNA

10

Where does molluscum contagiosum replicate?

Cytoplasm

11

Is HSV enveloped?

Yes

12

What is the HSV genome?

dsDNA

13

What is characteristic about chickenpox lesions?

Found in crops - multiple evolutionary stages in that area of the body

14

What virus is responsible for chickenpox?

Varicella-zoster virus

15

What is the cause of shingles?

Varicella-zoster virus reactivation

16

What family does varicella-zoster virus belong to?

Herpesviridae

17

Is varicella-zoster virus enveloped or non-enveloped?

Enveloped

18

What is the varicella-zoster virus genome?

dsDNA

19

Where does varicella-zoster virus maintain latency?

Trigeminal nerve

20

How many serotypes of varicella-zoster virus exist?

One

21

How is varicella-zoster virus diagnosed?

Tzanck smear, ELISA, latex agglutination

22

What type of vaccine is the varicella vaccine?

Live attenuated

23

The zoster vaccine is recommended for people of what age group?

Over age 60